Results 141 to 150 of about 153,127 (306)

Taking Into Account Insulin Resistance With Associated Hyperinsulinemia to Counteract the Development of Acute and Chronic Cardiovascular Diseases

Chronic Diseases and Translational Medicine, EarlyView.
Serafino Fazio, Flora Affuso
wiley   +1 more source

Lipoprotein(a), ABO Blood Types and Clinical Outcomes: Novel Findings and Clinical Implications in Patients With Chronic Coronary Syndrome

MedComm
This study aimed to investigate the effect of lipoprotein(a) (Lp(a)) on major adverse cardiovascular events (MACEs) among individuals with chronic coronary syndrome (CCS) according to ABO blood groups.
Hui‐Hui Liu, Chen‐Xi Song, Sha Li, Yan Zhang, Dong Yin, Wei‐Hua Song, Yuan‐Lin Guo, Cheng‐Gang Zhu, Na‐Qiong Wu, Rui‐Xia Xu, Qian Dong, Jie Qian, Yu‐Hui Zhang, Ke‐Fei Dou, Jian‐Jun Li   +14 more
doaj   +1 more source

Targeting vascular adhesion protein-1 and myeloperoxidase with a dual inhibitor SNT-8370 in preclinical models of inflammatory disease

Nature Communications
Inflammatory diseases are a major source of morbidity and mortality world-wide, the pathogenesis of which are characterised by the interplay of key pro-inflammatory and oxidative enzymes. Here, we report the development of a small molecule dual inhibitor
Elias Glaros, Jonathan Foot, Ben Rayner, Heidi Schilter, Yunjia Zhang, Martina Paumann-Page, Mauro M. Teixeira, Wolfgang Jarolimek, Shane R. Thomas   +8 more
doaj   +1 more source

Circulating Branched Chain Amino Acids and Cardiometabolic Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Branched chain amino acids (BCAAs) are essential for protein homeostasis, energy balance, and signaling pathways. Changes in BCAA homeostasis have emerged as pivotal contributors in the pathophysiology of several cardiometabolic diseases, including type ...
Keenan S. Fine, John T. Wilkins, Konrad T. Sawicki   +2 more
doaj   +1 more source

Cardiometabolic Diseases

JACC: Basic to Translational Science, 2023
openaire   +1 more source

Mental Health Conditions and Incident Cancer: A Prospective Cohort Study of 402,255 UK Biobank Participants

International Journal of Cancer, EarlyView.
Evidence suggests a potential association between mental health conditions and cancer risk, yet previous studies were limited by small samples and the use of self‐reported measures. Using data from the UK Biobank's large‐scale prospective population cohort over a median follow‐up of 13.4 years, this analysis demonstrates associations between depression,
Mohammed Sherif Amin, Solange Parra‐Soto, Ziyi Zhou, Shinya Nakada, Ike Dhiah Rochmawati, Carlos Celis‐Morales, Nancy Meligy, Jill P. Pell, Frederick K. Ho   +8 more
wiley   +1 more source

Macrophage energy metabolism in cardiometabolic disease

Molecular and Cellular Biochemistry
Abstract In a rapidly expanding body of literature, the major role of energy metabolism in determining the response and polarization status of macrophages has been examined, and it is currently a very active area of research. The metabolic flux through different metabolic pathways in the macrophage is interconnected and complex and could ...
Wong, Angela, Sun, Qiuyu, Latif, Ismail I., Karwi, Qutuba G.   +3 more
openaire   +2 more sources

The mitochondrial DNA copy number and ovary‐related reproductive disorders: A bidirectional two‐sample Mendelian randomization study

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 112-120, April 2025.
Abstract Objective In the present study, a bidirectional two‐sample Mendelian randomization approach was utilized to explore potential causal relationships between mitochondrial DNA copy number (mtDNA‐CN) and ovary‐related reproductive disorders (ORRDs), including ovarian dysfunction, ovarian cyst, polycystic ovary syndrome (PCOS), premature ovarian ...
Ke Peng, Xiao Han, Congquan Wu, Qiaowen Lu, Shujun Gao   +4 more
wiley   +1 more source

Nonlinear association of triglyceride‐glucose body mass index with all‐cause mortality in postmenopausal women, a retrospective cohort study: Evidence from the 2001 to 2014 National Health and nutrition examination survey

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The triglyceride‐glucose body mass index (TyG‐BMI) is a novel indicator combining an insulin resistance proxy (TyG index) with adiposity. It remains unclear how TyG‐BMI relates to long‐term mortality risk in postmenopausal women, a group prone to metabolic changes after menopause.
Xiliang Wang, Kaiyue Wang, Chang Tan, Yuexin Yu   +3 more
wiley   +1 more source

NuViva: Development of postpartum nutrition and exercise program implementing the FIGO pregnancy passport to reduce cardiometabolic risk

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy provides a unique opportunity to identify women at increased risk of future chronic disease, as adverse pregnancy outcomes (APOs) such as hypertensive disorders of pregnancy, gestational diabetes mellitus, preterm birth, placental complications, and fetal growth restriction are associated with later cardiometabolic morbidity. However,
Nikki M. W. Lee, So‐Ling C. Lau, Panda Hoi Yin Li, Kit Ying Tsoi, Liona C. Poon   +4 more
wiley   +1 more source