Results 191 to 200 of about 147,725 (290)

The SERCA-PLN-DWORF axis in cardiometabolic disease: mechanisms and therapeutic perspectives. [PDF]

Cardiovasc Diabetol
Kim OH, Noh SW, Choi JS, Jung Y, Oh BC.
europepmc   +1 more source

Psychiatric Safety of Tirzepatide in People With Obesity and No Known Major Psychopathology: A Post Hoc Analysis of SURMOUNT

Obesity, EarlyView.
ABSTRACT Objective This post hoc analysis assessed psychiatric changes with tirzepatide in adults with obesity, without known major psychopathology, from SURMOUNT‐1, SURMOUNT‐2, and SURMOUNT‐3. Methods In participants (N = 4056) treated with tirzepatide (5/10/15 mg or maximum tolerated dose 10/15 mg) versus placebo, depressive symptoms and suicidal ...
Thomas A. Wadden, Maria A. Oquendo, Robert F. Kushner, Dachuang Cao, Chrisanthi A. Karanikas, Afton Kechter, Madhumita A. Murphy   +6 more
wiley   +1 more source

Clonal Hematopoiesis of Indeterminate Potential and Cardiometabolic Disease: Challenges, Controversies and Future Perspectives. [PDF]

Int J Mol Sci
Anastasiou IA, Kounatidis D, Vallianou NG, Rebelos E, Karampela I, Dalamaga M.   +5 more
europepmc   +1 more source

Comorbidities and Cardiometabolic Disease

JACC: Heart Failure, 2018
Matthew Nayor, Danielle M. Enserro, Vanessa Xanthakis, Martin G. Larson, Emelia J. Benjamin, Jayashri Aragam, Gary F. Mitchell, Ramachandran S. Vasan   +7 more
openaire   +1 more source

Exploring Sleep, Energy Balance, and Weight Loss Maintenance After Bariatric Surgery in Adult Females: A Cross‐Sectional Study

Obesity, EarlyView.
ABSTRACT Objective This cross‐sectional study examined associations between sleep, body weight, body composition, appetite, and food reward after bariatric surgery. Methods A single 7‐day study period in 22 female adults (age, 53.5 ± 9.3 years; BMI, 35.5 ± 8.5 kg/m2; body fat: 44.9% ± 8.6%) who underwent bariatric surgery ≥ 1 year prior to enrollment ...
Hannah R. Koch, Derek C. Monroe, Steve Fordahl, Graham Finlayson, Laurie Wideman, Jessica McNeil   +5 more
wiley   +1 more source

Beyond the Sum of Their Parts: Frailty and Cardiometabolic Disease in Predicting Mortality. [PDF]

JACC Asia
Tang KS, Fan W.
europepmc   +1 more source

Efficacy and Safety of Tirzepatide in Japanese Participants With Obesity: A Subpopulation Analysis of the SURMOUNT‐1 Trial

Obesity, EarlyView.
ABSTRACT Objective This prespecified subpopulation analysis aimed to assess the efficacy and safety of once‐weekly tirzepatide versus placebo alongside lifestyle intervention in Japanese adults with obesity or overweight. Methods Data from 102 Japanese adults in the SURMOUNT‐1 trial with BMI ≥ 30 kg/m2 or ≥ 27 kg/m2 and ≥ 1 weight‐related comorbidity ...
Yasushi Ishigaki, Masamichi Yamada, Tomotaka Shingaki, Tomonori Oura, Iichiro Shimomura   +4 more
wiley   +1 more source

LIFE's essential 8: a roadmap for preventing cardiometabolic disease progression. [PDF]

Nutr Metab (Lond)
Siervo M, Guan Z.
europepmc   +1 more source

C/EBPα is Essential for Gonadal but Not Inguinal White Adipose Tissue Formation in Mice

Obesity, EarlyView.
Human genetics has linked the gene CEBPA to waist to hip ratio and adipose distribution. We generated mice with AdipoQ‐Cre driven deletion of Cebpa and found these mice to have a specific reduction in gonadal white adipose tissue and myriad other metabolic phenotypes.
Krista Y. Hu, Yu‐Lin Ma, Esme A. Dodge, Olivia A. B. Maguire, Caio V. Matias, Ryan P. Barney, Hector S. Himede, Juliana Gomez Pardo, Miriam Cepeda, Scott M. Gordon, Robert C. Bauer   +10 more
wiley   +1 more source

3-D biomechanics and epigenomics reveal atypical fibroblast responses in cardiometabolic disease. [PDF]

Am J Physiol Heart Circ Physiol
Ibrahim SY, Holdiness R, Thadisena A, Boyle KE, Jun SR, Bagchi RA.   +5 more
europepmc   +1 more source