Results 101 to 110 of about 305,984 (384)

Atrial remodelling and dysfunction in hypertrophic cardiomyopathy: prognostic role and therapeutic target

Frontiers in Cardiovascular Medicine
IntroductionHypertrophic cardiomyopathy (HCM) is a common genetic cardiac disease marked by abnormal ventricular hypertrophy. Recent studies have highlighted that left atrial (LA) remodelling—including dilation, fibrosis, and functional impairment—plays ...
Chiara Piazzai, Alessio Petrone, Andrea Stefanini, Flavio D’Ascenzi, Iacopo Olivotto, Iacopo Olivotto, Matteo Cameli   +6 more
doaj   +1 more source

Recommendations for participation in competitive and leisure time sport in athletes with cardiomyopathies, myocarditis, and pericarditis: position statement of the Sport Cardiology Section of the European Association of Preventive Cardiology (EAPC).

European Heart Journal, 2018
Myocardial diseases are associated with an increased risk of potentially fatal cardiac arrhythmias and sudden cardiac death/cardiac arrest during exercise, including hypertrophic cardiomyopathy, dilated cardiomyopathy, left ventricular non-compaction ...
A. Pelliccia, E. Solberg, M. Papadakis, P. Adami, A. Biffi, S. Caselli, A. La Gerche, J. Niebauer, A. Pressler, C. Schmied, L. Serratosa, M. Halle, F. van Buuren, M. Borjesson, F. Carré, N. Panhuyzen-Goedkoop, H. Heidbuchel, I. Olivotto, D. Corrado, G. Sinagra, Sanjay Sharma   +20 more
semanticscholar   +1 more source

A mutation update for the FLNC gene in myopathies and cardiomyopathies

Human Mutation, 2020
Filamin C (FLNC) variants are associated with cardiac and muscular phenotypes. Originally, FLNC variants were described in myofibrillar myopathy (MFM) patients.
J. Verdonschot, Els K. Vanhoutte, G. Claes, A. T. Helderman-van den Enden, J. Hoeijmakers, D. Hellebrekers, Amber de Haan, I. Christiaans, R. L. Lekanne Deprez, H. Boen, E. V. Van Craenenbroeck, B. Loeys, Y. M. Hoedemakers, Carlo L. Marcelis, M. Kempers, Esther Brusse, Jaap I van Waning, Annette F. Baas, Dennis Dooijes, F. Asselbergs, D. Barge-Schaapveld, Pieter Koopman, A. van den Wijngaard, S. Heymans, I. Krapels, Han G Brunner   +25 more
semanticscholar   +1 more source

A global perspective of arrhythmogenic right ventricular cardiomyopathy. [PDF]

, 2012
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a progressive inherited heart disease characterized by ventricular arrhythmias and sudden cardiac death especially in the young. ARVC has been traditionally associated with the Mediterranean basin,
Alhashemi, M, Elmaghawry, M, Yacoub, MH, Zorzi, A   +3 more
core   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

Role of cardiac MRI in nonischemic cardiomyopathies

Indian Heart Journal, 2016
Cardiac magnetic resonance (CMR) with its higher spatial resolution is considered the gold standard for evaluating ventricular mass, volumes, and ejection fraction. CMR can be used for accurate diagnosis of several conditions, especially cardiomyopathies.
Senthil Anand, Rajesh Janardhanan
doaj   +1 more source

Macrophage DCLK1 promotes obesity-induced cardiomyopathy via activating RIP2/TAK1 signaling pathway [PDF]

, 2023
Bin Yang, Yunjie Zhao, Wu Luo, Weiwei Zhu, Leiming Jin, Minxiu Wang, Lin Ye, Yi Wang, Guang Liang   +8 more
openalex   +1 more source

Adaptation and validation of the ACMG/AMP variant classification framework for MYH7-associated inherited cardiomyopathies: recommendations by ClinGen’s Inherited Cardiomyopathy Expert Panel

Genetics in Medicine, 2018
PurposeIntegrating genomic sequencing in clinical care requires standardization of variant interpretation practices. The Clinical Genome Resource has established expert panels to adapt the American College of Medical Genetics and Genomics/Association for
M. Kelly, C. Caleshu, A. Morales, J. Buchan, Zena T. Wolf, S. Harrison, S. Cook, Mitchell W Dillon, John Garcia, Eden V. Haverfield, J. Jongbloed, D. Macaya, A. Manrai, Kate M. Orland, G. Richard, Katherine G Spoonamore, Matthew Thomas, K. Thomson, L. Vincent, R. Walsh, H. Watkins, N. Whiffin, J. Ingles, J. P. van Tintelen, C. Semsarian, J. Ware, R. Hershberger, B. Funke   +27 more
semanticscholar   +1 more source

Takotsubo cardiomyopathy and sepsis: a systematic review [PDF]

, 2017
Takotsubo cardiomyopathy (TTC) is characterized by a systolic dysfunction localized in the apical and medial aspect of the left ventricle. It is usually related to physical or emotional stress.
Agarwal V, Costantino Ciallella, Geng S, Hutan Ashrafian, Lee S, Mariarosaria Aromatario, Maron BJ, Odigie-Okon E, Pullara A, Sarullo FM, Sato H, Sharkey SW, Sian Harding, Simone Cappelletti, Thanos Athanasiou, Xu RH   +15 more
core   +1 more source

Redox‐Responsive Tellurium‐Bridged Covalent Organic Frameworks/PEG Composites for Targeted Therapy of Diabetic Cardiomyopathy

Advanced Science, EarlyView.
This study unlocks the immense potential of COF@polymer nanocomposites as a multifunctional therapeutic platform for targeted drug delivery in diabetic cardiomyopathy. Abstract Diabetic cardiomyopathy, a major complication of diabetes, is strongly associated with elevated levels of glycated hemoglobin (HbA1c) and reactive oxygen species (ROS). However,
Jing Xue, Jialu Zhuang, Taotao Fan, Songtao Tang, Junjun Wang, Xiaohui Liu, Jian Liu, Jin Shi, Jiaji Li, Wanjun Li, Danyou Hu, Xiaoqian Zhang, Hua Wang, Guiyang Zhang   +13 more
wiley   +1 more source