Results 121 to 130 of about 305,984 (384)

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

open access: yesAdvanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi   +10 more
wiley   +1 more source

Inherited Cardiomyopathies: Genetics and Clinical Genetic Testing

open access: yesCardiovascular Innovations and Applications, 2017
Inherited cardiomyopathies are major causes of morbidity and mortality and include a group of cardiac disorders such as hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy, arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C), left ...
Guoliang Wang   +4 more
doaj   +1 more source

Clinical Potentials of Cardiomyocytes Derived from Patient-Specific Induced Pluripotent Stem Cells [PDF]

open access: yes, 2014
The lack of appropriate human cardiomyocyte-based experimental platform has largely hindered the study of cardiac diseases and the development of therapeutic strategies.
LAW, CY, Ng, KM, Tse, HF
core   +2 more sources

Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases

open access: yesAdvanced Science, EarlyView.
Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu   +9 more
wiley   +1 more source

FLNC pathogenic variants in patients with cardiomyopathies: Prevalence and genotype‐phenotype correlations

open access: yesClinical Genetics, 2019
Pathogenic variants in FLNC encoding filamin C have been firstly reported to cause myopathies, and were recently linked to isolated cardiac phenotypes. Our aim was to estimate the prevalence of FLNC pathogenic variants in subtypes of cardiomyopathies and
F. Ader   +18 more
semanticscholar   +1 more source

Molecular Basis of Inflammation in the Pathogenesis of Cardiomyopathies

open access: yesInternational Journal of Molecular Sciences, 2020
Cardiomyopathies (CMPs) represent a diverse group of heart muscle diseases, grouped into specific morphological and functional phenotypes. CMPs are associated with mutations in sarcomeric and non-sarcomeric genes, with several suspected epigenetic and ...
E. Monda   +18 more
semanticscholar   +1 more source

FIRST RESULTS OF MICROSPHERE EMBOLIZATION AS AN ALTERNATIVE FOR ALCOHOL IN PERCUTANEOUS TRANSLUMINAL SEPTAL MYOCARDIAL ABLATION [PDF]

open access: yes, 2011
Farrando Sicilia, Jordi; Fuente Fuente ...
Vriesendorp, Pieter A.   +5 more
core   +1 more source

Systematic Benchmarking of a Noise‐Tolerant Conductive Hydrogel Electrode for Epidermal Bioelectronics

open access: yesAdvanced Science, EarlyView.
General schematic of the approach. Abstract Conventional Silver/Silver Chloride (Ag/AgCl) electrodes remain the clinical standard for electrophysiological monitoring but are hindered by poor skin conformity, mechanical rigidity, and signal degradation, particularly under motion or sweat.
Nazmi Alsaafeen   +11 more
wiley   +1 more source

Reversible cardiomyopathies

open access: yesJournal of the Indian Academy of Echocardiography & Cardiovascular Imaging, 2018
Cardiac muscle dysfunction resulting in heart failure can be reversed with appropriate diagnosis and therapy in nearly 25%8211;50% of all nonischemic cardiomyopathies.
Anjaneyulu V Anne
doaj   +1 more source

2023 ESC Guidelines for the management of cardiomyopathies.

open access: yesEuropean Heart Journal, 2023
Elena Arbelo   +132 more
semanticscholar   +1 more source

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