Results 151 to 160 of about 269,027 (363)

Targeting the sarcomere in inherited cardiomyopathies

Nature Reviews Cardiology, 2022
Sarah J. Lehman, C. Crocini, L. Leinwand
semanticscholar   +1 more source

Novel Therapies for Prevention and Early Treatment of Cardiomyopathies.

Circulation Research, 2019
Heritable cardiomyopathies are a class of heart diseases caused by variations in a number of genetic loci. Genetic variants on one allele lead to either a degraded protein, which causes a haploinsufficiency of that protein, or a nonfunctioning protein ...
Giuliana G. Repetti, Christopher N Toepfer, J. Seidman, C. Seidman   +3 more
semanticscholar   +1 more source

FABP4 as a Mediator of Lipid Metabolism and Pregnant Uterine Dysfunction in Obesity

Advanced Science, EarlyView.
Obesity during late pregnancy contributes to uterine smooth muscle dysfunction, but the underlying mechanisms are unclear. This study identifies fatty acid binding protein 4 (FABP4) as a key player in the process, mediating excessive fatty acid uptake, lipid accumulation, and mitochondrial dysfunction in myometrial cells. FABP4 could be a novel uterine
Xuan Li, Huihui Yu, Ruixian Tian, Xingxing Wang, Ting Xing, Chenyi Xu, Tengteng Li, Xue Du, Qianqian Cui, Biao Yu, Yunxia Cao, Zongzhi Yin   +11 more
wiley   +1 more source

Pathobiology of cardiomyopathies: Experience at a Tertiary Care Center

Journal of the Practice of Cardiovascular Sciences, 2015
Background: Cardiomyopathies are a heterogeneous group of diseases of the myocardium associated with varied pathology. Pathology data from India are scarce.
Uma Nahar Saikia, Ajay Bahl, Baijayantimala Mishra, Mrinalini Sharma, Vandana Kumari, K K Talwar   +5 more
doaj   +1 more source

Suspended Tissue Open Microfluidic Patterning (STOMP)

Advanced Science, EarlyView.
Suspended Tissue Open Microfluidic Patterning (STOMP) is a method that enables precise spatial patterning within a single suspended tissue. By leveraging capillary pinning and open microfluidics, STOMP facilitates the creation of complex tissue interfaces such as diseased‐healthy boundaries and tissue‐tissue junctions. This method integrates mechanical
Amanda J. Haack, Lauren G. Brown, Alex J. Goldstein, Priti Mulimani, Jean Berthier, Asha R. Viswanathan, Irina Kopyeva, Jamison M. Whitten, Ariel Lin, Serena H. Nguyen, Thomas P. Leahy, Ella E. Bouker, Ruby M. Padgett, Natalie A. Mazzawi, Jodie C. Tokihiro, Ross C. Bretherton, Aaliyah Wu, Stephen J. Tapscott, Cole A. DeForest, Tracy E. Popowics, Erwin Berthier, Nathan J. Sniadecki, Ashleigh B. Theberge   +22 more
wiley   +1 more source

Biomedical Applications of Gadolinium‐Containing Biomaterials: Not Only MRI Contrast Agent

Advanced Science, EarlyView.
This paper summarizes the latest applications and potential mechanisms of the rare earth element gadolinium in biomedical fields, in addition to its traditional application as an MRI contrast agent, including osteogenesis, antimicrobial, antitumor, bioimaging, bioprobes, and so on.
Xingtong Pan, Menglong Hu, Likun Wu, Erfan Wei, Qiyue Zhu, Letian Lv, Xiuyun Xv, Xinyi Dong, Hao Liu, Yunsong Liu   +9 more
wiley   +1 more source

Prolonged Neuropsychiatric Disability and Cardiomyopathy in Acute Intermittent Porphyria [PDF]

, 1960
M. D. Eilenberg, B. A. Scobie
openalex   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

Advanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan, Jingyi Qi, Yi Xia, Chang Fan, Teng Xu, Xu Zhang, Jiaxin Shi, Chenxuan Wang, Yitong Cheng, Dongyuan Zhang, Rong Liu, Yinhua Zhu, Changchang Cao, Dekui Jin, Peng An, Yongting Luo, Junjie Luo   +16 more
wiley   +1 more source

The Ultra Low Frequency Force Ballistocardiograph in Acute Cardiomyopathy [PDF]

, 1967
Brendan Phibbs, CHARLES R. LOWE, Roy W. Holmes   +2 more
openalex   +1 more source

New Developments in Magnetic Resonance Imaging of Myocardial Diseases – Technical Aspects and Clinical Applications

Journal of Interdisciplinary Medicine, 2017
Cardiac magnetic resonance imaging is an evolving imaging method that can be used in cardiovascular pathology evaluation. Technological developments have increased the clinical utility of cardiac magnetic resonance in the exploration of various cardiac ...
Morariu Mirabela, Bordi Lehel, Opincariu Diana, Ratiu Alexandra Mihaela, Condrea Sebastian, Benedek Annabell, Benedek Theodora   +6 more
doaj   +1 more source