Results 21 to 30 of about 47,826 (191)

Cardiomyopathies [PDF]

, 2018
The cardiomyopathies are a heterogeneous collection of heart muscle disorders with diverse genetic and non-genetic aetiologies. The advent of molecular genetics and next-generation sequencing has transformed understanding of the mechanisms of disease ...
Yavari, Arash, Harper, AR, Harper, Andrew, Ashrafian, H, Ashrafian, Houman, Chan, K, Chan, Kenneth, Yavari, A   +7 more
core   +2 more sources

Cardiomyopathies.

Acta bio-medica : Atenei Parmensis, 2019
The most common cardiomyopathies often present to primary care physicians with similar symptoms, despite the fact that they involve a variety of phenotypes and etiologies (1). Many have signs and symptoms common in heart failure, such as reduced ejection fraction, peripheral edema, fatigue, orthopnea, exertion dyspnea, paroxysmal nocturnal dyspnea ...
Precone, Vincenza, Krasi, Geraldo, Guerri, Giulia, Madureri, Alberto, Piazzani, Mariangela, Michelini, Sandro, Barati, Shila, Maniscalchi, Tiziana, Bressan, Simone, Bertelli, Matteo   +9 more
openaire   +2 more sources

Targeting lipid metabolism as a new therapeutic strategy for inherited cardiomyopathies

Frontiers in Cardiovascular Medicine, 2023
Inherited cardiomyopathies caused by pathological genetic variants include multiple subtypes of heart disease. Advances in next-generation sequencing (NGS) techniques have allowed for the identification of numerous genetic variants as pathological ...
Karen R. Gaar-Humphreys, Karen R. Gaar-Humphreys, Alyssa van den Brink, Alyssa van den Brink, Mark Wekking, Mark Wekking, Folkert W. Asselbergs, Folkert W. Asselbergs, Frank G. van Steenbeek, Frank G. van Steenbeek, Frank G. van Steenbeek, Magdalena Harakalova, Magdalena Harakalova, Magdalena Harakalova, Jiayi Pei, Jiayi Pei, Jiayi Pei   +16 more
doaj   +1 more source

Dilated cardiomyopathies and non-compaction cardiomyopathy [PDF]

Herz, 2020
AbstractDilated cardiomyopathy (DCM) is the most common form of cardiomyopathy and one of the most common causes of heart failure. It is characterized by left or biventricular dilation and a reduced systolic function. The causes are manifold and range from myocarditis to alcohol and other toxins, to rheumatological, endocrinological, and metabolic ...
Hänselmann, A., Veltmann, C., Bauersachs, J., Berliner, D.   +3 more
openaire   +2 more sources

Arrhythmogenic Cardiomyopathy [PDF]

Circulation Research, 2017
Arrhythmogenic cardiomyopathy is an inherited heart muscle disorder, predisposing to sudden cardiac death, particularly in young patients and athletes. Pathological features include loss of myocytes and fibrofatty replacement of right ventricular myocardium; biventricular involvement is often observed.
Corrado, Domenico, Basso, Cristina, Judge, Daniel P.   +2 more
openaire   +3 more sources

Transcriptome data analysis of primary cardiomyopathies reveals perturbations in arachidonic acid metabolism

Frontiers in Cardiovascular Medicine, 2023
IntroductionCardiomyopathies are complex heart diseases with significant prevalence around the world. Among these, primary forms are the major contributors to heart failure and sudden cardiac death.
Pankaj Kumar Chauhan, Ramanathan Sowdhamini, Ramanathan Sowdhamini, Ramanathan Sowdhamini   +3 more
doaj   +1 more source

Translating emerging molecular genetic insights into clinical practice in inherited cardiomyopathies. [PDF]

, 2018
Cardiomyopathies are primarily genetic disorders of the myocardium associated with higher risk of life-threatening cardiac arrhythmias, heart failure, and sudden cardiac death.
Medeiros-Domingo, Argelia, Asatryan, Babken   +1 more
core   +2 more sources

The Feline Cardiomyopathies: 2. Hypertrophic cardiomyopathy

Journal of Feline Medicine and Surgery, 2021
Practical relevance: Hypertrophic cardiomyopathy (HCM) is the most common form of feline cardiomyopathy observed clinically and may affect up to approximately 15% of the domestic cat population, primarily as a subclinical disease. Fortunately, severe HCM, leading to heart failure or arterial thromboembolism (ATE)
Kittleson, Mark D, Côté, Etienne
openaire   +3 more sources

Prelamin A mediates myocardial inflammation in dilated and HIV-associated cardiomyopathies [PDF]

, 2019
Cardiomyopathies are complex heart muscle diseases that can be inherited or acquired. Dilated cardiomyopathy can result from mutations in LMNA, encoding the nuclear intermediate filament proteins lamin A/C. Some LMNA mutations lead to accumulation of the
Vizcay-Barrena, G., Russo, M.A., Hayward, R., dos Remedios, C.G., Protti, A., Zammit, P.S., Ehler, E., Ahmad, S.M., Shah, A.M., Frustaci, A., Brayson, D., Shanahan, C.M., Chimenti, C., Verardo, R.   +13 more
core   +1 more source

A green tea extract catechin EGCg: Therapeutic potential for pediatric cardiomyopathies

Pediatric Discovery, 2023
Cardiomyopathies comprise a group of disorders wherein the primary defect is in cardiac myocytes. The common forms of pediatric cardiomyopathies, classified according to their morphological and functional manifestations, include dilated cardiomyopathy ...
Junjun Quan, Dustin Gerber, Ang Li, Xupei Huang, Jie Tian   +4 more
doaj   +1 more source