Results 31 to 40 of about 47,826 (191)
Cardiomyopathies de l'enfant [PDF]
Les cardiomyopathies sont des maladies peu répandues et ceci est d’autant plus vrai chez les enfants. La cardiomyopathie dilatée est la forme la plus courante des cardiomyopathies.
Bendahane, Hamza Zohir +1 more
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Cardiomyocyte dysfunction in inherited cardiomyopathies
Inherited cardiomyopathies form a heterogenous group of disorders that affect the structure and function of the heart. Defects in the genes encoding sarcomeric proteins are associated with various perturbations that induce contractile dysfunction and ...
Mügge, Andreas (Prof. Dr. med.) +3 more
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Background: Cardiac myosin inhibitors (CMIs), including Mavacamten and Aficamten, have emerged as a groundbreaking treatment for hypertrophic cardiomyopathy (HCM).
Ali Amr +7 more
doaj +1 more source
Human-induced pluripotent stem cells in modeling inherited cardiomyopathies
Our current understanding of molecular mechanisms of cardiomyopathies has been elucidated from genetic animal models. Induced pluripotent stem cells (iPSCs) can provide a platform to improve our understanding of familial cardiomyopathies diseases.
Subhoshree Ghose +3 more
doaj +1 more source
MitraClip (Abbott Laboratories, Abbott Park, IL) is validated in high-risk patients with severe degenerative mitral regurgitation (MR); however, it is not well established for functional MR in hypertrophic cardiomyopathy (HCM).
Catherine Bourque, MD +8 more
doaj +1 more source
Pediatric cardiomyopathies are rare diseases with an annual incidence of 1.1 to 1.5 per 100 000. Dilated and hypertrophic cardiomyopathies are the most common; restrictive, noncompaction, and mixed cardiomyopathies occur infrequently; and arrhythmogenic ...
Thrush, Philip T +37 more
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A very rare cause of pre‐capillary pulmonary hypertension: The PAMI syndrome
We report the first known case of PAMI syndrome associated with pulmonary arterial hypertension (PAH) with a positive response to cyclophosphamide and pulmonary vasodilators. The patient's history began at 7 months with severe pancytopenia and fever.
Manuela Iseppi +5 more
doaj +1 more source
Targeting ferroptosis as a promising therapeutic strategy to treat cardiomyopathy
Cardiomyopathies are a clinically heterogeneous group of cardiac diseases characterized by heart muscle damage, resulting in myocardium disorders, diminished cardiac function, heart failure, and even sudden cardiac death.
Huiyan Sun +6 more
doaj +1 more source
The disease of the heart muscle may occur secondarily to common diseases, such as ischemic, hypertensive and valvular, among others. However, there is a group of conditions with intrinsic myocardial involvement from gene or multifactorial etiology, and ...
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