Results 41 to 50 of about 44,322 (189)

Cardiomyopathies

, 2018
The cardiomyopathies are a heterogeneous collection of heart muscle disorders with diverse genetic and non-genetic aetiologies. The advent of molecular genetics and next-generation sequencing has transformed understanding of the mechanisms of disease ...
Yavari, Arash, Harper, AR, Harper, Andrew, Ashrafian, H, Ashrafian, Houman, Chan, K, Chan, Kenneth, Yavari, A   +7 more
core   +2 more sources

A green tea extract catechin EGCg: Therapeutic potential for pediatric cardiomyopathies

Pediatric Discovery, 2023
Cardiomyopathies comprise a group of disorders wherein the primary defect is in cardiac myocytes. The common forms of pediatric cardiomyopathies, classified according to their morphological and functional manifestations, include dilated cardiomyopathy ...
Junjun Quan, Dustin Gerber, Ang Li, Xupei Huang, Jie Tian   +4 more
doaj   +1 more source

Eclipsed Functional Mitral Regurgitation Destabilizing Hypertrophic Cardiomyopathy: An Unusual Case Treated With MitraClipNovel Teaching Points

CJC Open, 2021
MitraClip (Abbott Laboratories, Abbott Park, IL) is validated in high-risk patients with severe degenerative mitral regurgitation (MR); however, it is not well established for functional MR in hypertrophic cardiomyopathy (HCM).
Catherine Bourque, MD, Marina Dijos, MD, Lionel Leroux, MD, Louis Labrousse, MD, Alexandre Metras, MD, Matthieu Michaud, MD, Marie Hébert, MD, Patricia Réant, MD, Stéphane Lafitte, MD   +8 more
doaj   +1 more source

Cardiomyocyte Dysfunction in Inherited Cardiomyopathies

, 2021
Inherited cardiomyopathies form a heterogenous group of disorders that affect the structure and function of the heart. Defects in the genes encoding sarcomeric proteins are associated with various perturbations that induce contractile dysfunction and ...
Nazha Hamdani, Heidi Budde, Andreas Mügge, Roua Hassoun   +3 more
core   +2 more sources

A very rare cause of pre‐capillary pulmonary hypertension: The PAMI syndrome

Pulmonary Circulation, 2023
We report the first known case of PAMI syndrome associated with pulmonary arterial hypertension (PAH) with a positive response to cyclophosphamide and pulmonary vasodilators. The patient's history began at 7 months with severe pancytopenia and fever.
Manuela Iseppi, Giulio Savonitto, Alberto Tommasini, Alessia Pin, Gianfranco Sinagra, Davide Stolfo   +5 more
doaj   +1 more source

Human-induced pluripotent stem cells in modeling inherited cardiomyopathies

Journal of the Practice of Cardiovascular Sciences, 2015
Our current understanding of molecular mechanisms of cardiomyopathies has been elucidated from genetic animal models. Induced pluripotent stem cells (iPSCs) can provide a platform to improve our understanding of familial cardiomyopathies diseases.
Subhoshree Ghose, Anju Sharma, Aishwarya Agarwal, Shantanu Sengupta   +3 more
doaj   +1 more source

Assessing the Applicability of Cardiac Myosin Inhibitors for Hypertrophic Cardiomyopathy Management in a Large Single Center Cohort

Reviews in Cardiovascular Medicine
Background: Cardiac myosin inhibitors (CMIs), including Mavacamten and Aficamten, have emerged as a groundbreaking treatment for hypertrophic cardiomyopathy (HCM).
Ali Amr, Elham Kayvanpour, Christoph Reich, Jan Koelemen, Shamily Asokan, Norbert Frey, Benjamin Meder, Farbod Sedaghat-Hamedani   +7 more
doaj   +1 more source

Pediatric Cardiomyopathies

, 2017
Pediatric cardiomyopathies are rare diseases with an annual incidence of 1.1 to 1.5 per 100 000. Dilated and hypertrophic cardiomyopathies are the most common; restrictive, noncompaction, and mixed cardiomyopathies occur infrequently; and arrhythmogenic ...
Thrush, Philip T, Stephanie M. Ware, Wendy K. Chung, Steven D. Colan, Paul Kantor, Kantor, Paul, Daphne T. Hsu, Czachor, Jason D, Rossano, Joseph W, Castleberry, Chesney D, Addonizio, Linda J, Hiedy Razoky, Erin M. Miller, Lamour, Jacqueline M, Miller, Erin M, Lipshultz, Steven E, Steven E. Lipshultz, Teresa M. Lee, Towbin, Jeffrey A, Jeffrey A. Towbin, Ashley Hill, Jacqueline M. Lamour, Colan, Steven D, Joseph W. Rossano, Razoky, Hiedy, Jason D. Czachor, Jefferies, John L, Hsu, Daphne T, Hill, Ashley, Lal, Ashwin K, Linda J. Addonizio, John L. Jefferies, Philip T. Thrush, Chesney D. Castleberry, Lee, Teresa M, Ware, Stephanie M, Ashwin K. Lal, Chung, Wendy K   +37 more
core   +1 more source

Diagnosis of cardiomyopathies: tips and tricks for internists and general practitioners

Cardiogenetics, 2017
Cardiomyopathies are little known to internists and general practitioners (GPs), and not always able to arouse the interest of cardiologists. Probably, this happens because cardiomyopathies are perceived as rare and complex disorders, a prerogative of a ...
Giuseppe Palmiero, Guido Carlomagno, Giacomo Lucivero   +2 more
doaj   +1 more source