Results 141 to 150 of about 66,165 (233)

Noradrenergic and cholinergic innervation of the normal human heart and changes associated with cardiomyopathy

open access: yesThe Anatomical Record, Volume 309, Issue 2, Page 417-450, February 2026.
Abstract Autonomic nerves are crucial in cardiac function and pathology. However, data on the distribution of cholinergic and noradrenergic nerves in normal and pathologic human hearts is lacking. Nonfailing donor hearts were pressure‐perfusion fixed, imaged, and dissected. Left ventricular cardiomyopathy samples were also obtained.
Peter Hanna   +16 more
wiley   +1 more source

Current Trends in Duchenne Muscular Dystrophy Research and Therapy: 3D Cardiac Modelling

open access: yesJournal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Duchenne muscular dystrophy (DMD), caused by dystrophin deficiency, presents a multifaceted challenge that affects both skeletal muscle function and cardiomyocyte homeostasis, causing progressive degeneration and life‐threatening cardiac complications by adolescence.
Marta Przymuszała   +3 more
wiley   +1 more source

Novel Echocardiographic Index for Risk Stratification of Ventricular Arrhythmias and Mortality Based on Right Ventricular Function

open access: yesJournal of Arrhythmia, Volume 42, Issue 1, February 2026.
Patients undergoing ICD implantation with both preprocedural echocardiography and cardiac magnetic resonance (CMR) were retrospectively analyzed to assess right ventricular (RV) function. Echocardiographic RV fractional area change (RVFAC) and the contraction pressure index (CPI), as well as CMR‐derived RV ejection fraction (RVEF), predicted ...
Toshinori Chiba   +11 more
wiley   +1 more source

Clinical care of family members of patients with dilated cardiomyopathy. [PDF]

open access: yesEur Heart J
Verdonschot JAJ   +20 more
europepmc   +1 more source

ATAD3 duplications bridge mitochondrial diseases and Aicardi–Goutières syndrome

open access: yesDevelopmental Medicine &Child Neurology, Volume 68, Issue 2, Page 287-294, February 2026.
ATAD3 locus duplications cause a severe neonatal mitochondrial disorder with neuroimaging features resembling interferonopathies, and suggest a mitochondrial nucleic acid‐triggered interferon response. Plain language summary: https://onlinelibrary.wiley.com/doi/10.1111/dmcn.16446 Abstract A recurrent 68‐kb heterozygous duplication of the ATAD3 locus ...
Pauline Planté‐Bordeneuve   +26 more
wiley   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, Volume 16, Issue 1, Page 178-198, January 2026.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

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