Results 11 to 20 of about 591,365 (304)

Genetics of Dilated Cardiomyopathy

Annual Review of Medicine, 2021
Dilated cardiomyopathy (DCM) is defined as dilation and/or reduced function of one or both ventricles and remains a common disease worldwide. An estimated 40% of cases of familial DCM have an identifiable genetic cause. Accordingly, there is a fast-growing interest in the field of molecular genetics as it pertains to DCM. Many gene mutations have been
Ramone, Eldemire, Luisa, Mestroni, Matthew R G, Taylor   +2 more
openaire   +3 more sources

Immune-inflammatory concept of the pathogenesis of chronic heart failure in dogs with dilated cardiomyopathy [PDF]

Veterinary World, 2019
Background: Dilated cardiomyopathy is common in dogs. This form of cardiomyopathy is the main cause of death due to heart disease in dogs. Death can occur suddenly in clinically normal animals as a result of the progression of congestive heart failure ...
Yu Vatnikov, A. Rudenko, P. Rudenko, Ev Kulikov, A. Karamyan, V. Lutsay, I. Medvedev, V. Byakhova, E. Krotova, M. Molvhanova   +9 more
doaj   +1 more source

NON ISCHEMIC CARDIOMYOPATHY – A CASE REPORT

Liaquat Medical Research Journal, 2023
Cardiomyopathies are a group of diseases characterized by the structural and functional abnormalities of the heart muscles in the absence of other illnesses that might be responsible for the observed myocardial anomaly.
Anny Ashiq Ali Anny Ashiq Ali, Saba Muhammad Nazim   +1 more
doaj   +1 more source

An Evidence-based Assessment of Genes in Dilated Cardiomyopathy

medRxiv, 2020
Supplemental Digital Content is available in the text. Background: Each of the cardiomyopathies, classically categorized as hypertrophic cardiomyopathy, dilated cardiomyopathy (DCM), and arrhythmogenic right ventricular cardiomyopathy, has a signature ...
MS Elizabeth Jordan, MS Cgc Laiken Peterson, MD PhD Tomohiko Ai, MD Babken Asatryan, PhD Lucas Bronicki, Facmg Dabmgg, Mgc Cgc Emily Brown, PhD Rudy Celeghin, MSc Matthew Edwards, DipRCPath, MS Cgc Judy Fan, PhD Mph Jodie Ingles, S. C. A. Cynthia A. James, PhD Fccmg Olga Jarinova, PhD Mgc Renee Johnson, MD Daniel P. Judge, MD Najim Lahrouchi, PhD Ronald H. Lekanne Deprez, PhD R. Thomas Lumbers, PhD Francesco Mazzarotto, A. Medeiros, M. C. Rebecca L. Miller, MS Cgc Ana Morales, MS Cgc Brittney Murray, Mbbs Fracp Stacey Peters, PhD Kalliopi Pilichou, MD Alexandros Protonotarios, Mbbs PhD Mph Christopher Semsarian, MS PalakShahMD, PhD Petros Syrris, PhD Courtney Thaxton, M. P. J. Peter van Tintelen, PhD Roddy Walsh, MD Jessica Wang, Mrcp PhD James Ware, MD Ray E. Hershberger, London   +36 more
semanticscholar   +1 more source

Desmoplakin Cardiomyopathy, a Fibrotic and Inflammatory Form of Cardiomyopathy Distinct from Typical Dilated or Arrhythmogenic Right Ventricular Cardiomyopathy

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Mutations in desmoplakin (DSP), the primary force transducer between cardiac desmosomes and intermediate filaments, cause an arrhythmogenic form of cardiomyopathy that has been variably ...
Eric Smith, N. Lakdawala, N. Papoutsidakis, G. Aubert, A. Mazzanti, A. McCanta, P. Agarwal, P. Arscott, Lisa M. Dellefave‐Castillo, E. Vorovich, K. Nutakki, Lisa D. Wilsbacher, S. Priori, D. Jacoby, E. McNally, A. Helms   +15 more
semanticscholar   +1 more source

Hypertrophic cardiomyopathy is associated with dilated sinus of Valsalva: A case-control study

International Journal of Cardiology: Heart & Vasculature, 2023
Background: We aimed to test the hypothesis that there is an association between hypertrophic cardiomyopathy and dilated aorta in a case-control, matched-design fashion. Methods: Of 65,843 studies done from November 2011 to December 2015, we found, after
Ji Ae Yoon, Mirza Mujadil Ahmad, Afshan Husain, Lily Ann Walson, Muhammad Nabeel Syed, A. Jamil Tajik, Khawaja Afzal Ammar   +6 more
doaj   +1 more source

Epigenetics in dilated cardiomyopathy [PDF]

Current Opinion in Cardiology, 2019
Characterized by enlarged ventricle and loss of systolic function, dilated cardiomyopathy (DCM) has the highest morbidity among all the cardiomyopathies. Although it is well established that DCM is typically caused by mutations in a large number of genes, there is an emerging appreciation for the contribution of epigenetic alteration in the development
Yu, Junyi, Zeng, Chunyu, Wang, Yibin
openaire   +4 more sources

Dilated cardiomyopathy and aldosteronoma: a causal link?

ESC Heart Failure, 2020
The aim of this study is to reveal the causal relationship between dilated cardiomyopathy and aldosteronoma. A 44‐year‐old male dilated cardiomyopathy patient with aldosteronoma, who demonstrated a worse cardiac function after 1 year therapy with ...
Jiyu Zhang, Jin Yang, Yueliang Li
doaj   +1 more source

Incidence rates of dilated cardiomyopathy in adult first-degree relatives versus matched controls

International Journal of Cardiology: Heart & Vasculature, 2022
Background: The incidence rates and importance of traditional risk factors in dilated cardiomyopathy among first-degree relatives are unknown. Methods and Results: We identified all probands with dilated cardiomyopathy (n = 13,714, mean age at diagnosis ...
Charlotte Andersson, Morten Schou, Brian Schwartz, Ramachandran S. Vasan, Mia Nielsen Christiansen, Maria D'Souza, Peter Weeke, Lars Køber, Alex H. Christensen, Gunnar H. Gislason, Christian Torp-Pedersen   +10 more
doaj   +1 more source

Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

Nature Communications, 2020
Dilated cardiomyopathy (DCM) is an important cause of heart failure and the leading indication for heart transplantation. Many rare genetic variants have been associated with DCM, but common variant studies of the disease have yielded few associated loci.
J. Pirruccello, Alexander G. Bick, Minxian Wang, M. Chaffin, S. Friedman, Jie Yao, Xiuqing Guo, B. Venkatesh, K. Taylor, W. Post, S. Rich, J. Lima, J. Rotter, A. Philippakis, S. Lubitz, P. Ellinor, A. Khera, S. Kathiresan, Krishna G. Aragam   +18 more
semanticscholar   +1 more source