Results 191 to 200 of about 66,165 (233)

The Immunological Consequences of Clonal Hematopoiesis in Heart Failure

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Inflammation is increasingly recognized as a central driver of heart failure (HF), particularly in older adults, yet the underlying immune mechanisms remain diverse and incompletely understood. Clonal hematopoiesis (CH), defined by the expansion of somatically mutated hematopoietic clones, has emerged as a risk factor for the development of ...
Megan A. Evans, Kenneth Walsh
wiley   +1 more source

Catheter Ablation Is Associated With a Decrease in Major Adverse Cardiovascular Events and All‐Cause Mortality in Patients With Atrial Fibrillation and Obstructive Sleep Apnea

open access: yesJournal of Cardiovascular Electrophysiology, Volume 37, Issue 1, Page 36-45, January 2026.
ABSTRACT Introduction Obstructive sleep apnea (OSA) is a common risk factor for the development and progression of atrial fibrillation (AF). Whether catheter ablation for AF management in patients with coexisting OSA yields survival benefit remains unclear.
Ghassan Bidaoui   +16 more
wiley   +1 more source

TRIM52 Protects Against Doxorubicin‐Induced Cardiac Inflammation, Oxidative Stress and Cardiac Injury

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT Tripartite motif 52 (TRIM52) has been identified as a key regulator of inflammatory responses. However, its involvement in doxorubicin (DOX)‐induced cardiotoxicity (DIC) and the underlying molecular mechanisms remain poorly understood. To investigate the functional role of TRIM52, we employed an adeno‐associated virus serotype 9 (AAV9 ...
Zhaoxia Zhang   +8 more
wiley   +1 more source

Cardiomyopathy in valosin-containing protein multisystem proteinopathy: Evaluation, diagnosis, and management. [PDF]

open access: yesAm Heart J Plus
Chan JM   +9 more
europepmc   +1 more source

Aldehyde Dehydrogenase‐2 Alleviates Septic Myocardial Injury by Inhibiting Caspase‐11‐Mediated Noncanonical Pyroptosis

open access: yesCardiovascular Therapeutics, Volume 2026, Issue 1, 2026.
Purpose The purpose of this study is to investigate the role of aldehyde dehydrogenase‐2 (ALDH2) in septic myocardial injury, focusing on noncanonical pyroptosis. Methods In vivo, C57BL/6J mice were divided into five groups: Sham, cecal ligation and puncture (CLP), CLP + Alda‐1 (ALDH2 agonist), Sham + dimethyl sulfoxide (DMSO, solvent control), and CLP 
Huan Liang   +8 more
wiley   +1 more source

Developing Del2Phen: A Novel Phenotype Description Tool for Chromosome Deletions

open access: yesHuman Mutation, Volume 2026, Issue 1, 2026.
Information on the health‐related consequences of rare chromosome disorders is often limited, posing challenges for both patients and their families. The Chromosome 6 Project aims to bridge this knowledge gap for structural aberrations involving chromosome 6 by providing parents of affected children with information on the expected phenotypes of their ...
Eleana Rraku   +8 more
wiley   +1 more source

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