Results 61 to 70 of about 445,510 (263)
Advanced Science, EarlyView.Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan +16 more
wiley +1 more source
Brazilian Journal of Infectious DiseasesThe idiopathic dilated cardiomyopathy (IDMC) is a disease of the cardiac muscle characterized by systolic dilation and/or dysfunction of one or both ventricles, symptoms of congestive heart failure and risk of early death.
Francisco J.F.B. Reis +4 more
doaj +1 more source
Normal Coronary Artery Patient Presenting with Left Ventricular Aneurysm
Case Reports in Medicine, 2011 Left ventricular aneurysm (LVA) is one of the most important complications of myocardial infarction LVA is strictly defined as a distinct area of abnormal left ventricular diastolic contour with systolic dyskinesia or paradoxical bulging.
Hakan Altay +3 more
doaj +1 more source
Dilated Cardiomyopathy: Genetic Determinants and Mechanisms
Circulation Research, 2017 Nonischemic dilated cardiomyopathy (DCM) often has a genetic pathogenesis. Because of the large number of genes and alleles attributed to DCM, comprehensive genetic testing encompasses ever-increasing gene panels.
E. McNally, L. Mestroni
semanticscholar +1 more source
Dilatations of categories [PDF]
arXiv, 2023 Dilatations modify categories by imposing that some morphisms factorize through some others. This is formalized by a universal property. This text is devoted to introduce and study this construction. Examples of dilatations of categories include localizations of categories and dilatations of rings.
arxiv
Evolving concepts in dilated cardiomyopathy
European Journal of Heart Failure, 2018 Dilated cardiomyopathy (DCM) represents a particular aetiology of systolic heart failure that frequently has a genetic background and usually affects young patients with few co‐morbidities.
M. Merlo +5 more
semanticscholar +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cystic kidney diseases (CyKD) are a diverse group of disorders affecting more than 1 in 1000 individuals. Over 120 genes are implicated, primarily encoding components of the primary cilium, transcription factors, and morphogens. Prognosis varies greatly by molecular diagnosis. Causal variants are not identified in 10%–60% of individuals due to
Deborah Watson +10 more
wiley +1 more source
Minimal unitary dilations for commuting contractions [PDF]
arXiv, 2022 For commuting contractions $T_1,\dots ,T_n$ acting on a Hilbert space $\mathcal H$ with $T=\prod_{i=1}^n T_i$, we show that $(T_1, \dots, T_n)$ dilates to commuting isometries $(V_1, \dots , V_n)$ on the minimal isometric dilation space of $T$ with $V=\prod_{i=1}^n V_i$ being the minimal isometric dilation of $T$ if and only if $(T_1^*, \dots , T_n^*)$
arxiv
Dilated cardiomyopathy in children
Journal of the American College of Cardiology, 1988 Dilated cardiomyopathy is a rare but serious disease in children. Clinical manifestations are primarily due to impaired systolic function of the left ventricle. Diagnostic evaluation is important to exclude masquerading cardiac abnormalities and to assess the degree of myocardial dysfunction.
openaire +3 more sources
Incidence rates of dilated cardiomyopathy in adult first-degree relatives versus matched controls
International Journal of Cardiology: Heart & Vasculature, 2022 Background: The incidence rates and importance of traditional risk factors in dilated cardiomyopathy among first-degree relatives are unknown. Methods and Results: We identified all probands with dilated cardiomyopathy (n = 13,714, mean age at diagnosis ...
Charlotte Andersson +10 more
doaj