Results 171 to 180 of about 91,175 (237)

H2FPEF and HFA‐PEFF scores for heart failure risk stratification in hypertrophic cardiomyopathy patients

ESC Heart Failure, Volume 12, Issue 3, Page 2225-2238, June 2025.
Abstract Aims H2FPEF and HFA‐PEFF scores have demonstrated prognostic value in heart failure (HF) with preserved ejection fraction. This study aimed to explore the value of the H2FPEF and HFA‐PEFF scores for HF risk stratification in patients with hypertrophic cardiomyopathy (HCM).
Yi‐Peng Gao, Hong‐Yun Liu, Xiao‐Jun Bi, Jie Sun, Ying Zhu, Wei Zhou, Ya‐Ting Fan, Xue‐Qing Cheng, Pei‐Na Huang, Ya‐Ni Liu, You‐Bin Deng   +10 more
wiley   +1 more source

Advancing diagnostics and therapy in transthyretin amyloid cardiomyopathy

ESC Heart Failure, Volume 12, Issue 3, Page 1529-1531, June 2025.
Katarzyna Holcman, Michał Tkaczyszyn
wiley   +1 more source

Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy

ESC Heart Failure, Volume 12, Issue 3, Page 2256-2266, June 2025.
Abstract Aims It was recently demonstrated that the intracellular signalling phosphatase calcineurin is subject to cleavage by the protease calpain, resulting in a truncated calcineurin fragment that is a strong inductor of myocardial hypertrophy. We now address the question of whether inhibition of calpain function in cardiomyocytes, and thereby ...
Gregor Sachse, Johanna Tennigkeit, Nikolaos Pagonas, Philipp Hillmeister, Ivo Buschmann, Martin Czolbe, Peter Nordbeck, Joachim Schmitt, Daniel Patschan, Oliver Ritter   +9 more
wiley   +1 more source

Unravelling the Genotype of the Apical Variant of Hypertrophic Cardiomyopathy in a Swedish Cohort. [PDF]

Genes (Basel)
Kissopoulou A, Ellegård R, Fernlund EI, Karlsson JE, Green H, Gunnarsson C.   +5 more
europepmc   +1 more source

Genetic testing and counseling for hypertrophic cardiomyopathy: An evidence‐based practice resource of the National Society of Genetic Counselors

Journal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a common hereditary condition affecting approximately 1 in 500 adults. It is characterized by marked clinical heterogeneity with individuals experiencing minimal to no symptoms, while others may have more severe outcomes including heart failure and sudden cardiac death.
Erin M. Miller, Emily Brown, Susan Christian, Melissa A. Kelly, Linda M. Knight, Sara Saberi, Christina Rigelsky, Jodie Ingles   +7 more
wiley   +1 more source

Arrhythmias and Sudden Death: What is New in Hypertrophic Cardiomyopathy? [PDF]

Card Fail Rev
Rajan D, Zörner CR, Hansen ML, Tfelt-Hansen J.   +3 more
europepmc   +1 more source

The case for integrating genetic counselors into primary care: A paradigm shift for our profession

Journal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract The integration of genetic counselors (GCs) into primary care represents an opportunity for a transformative shift in healthcare delivery, bridging the gap between the historical medical genetics delivery model and the increasing need for genetic services.
Vivian Pan, Natasha Berman, Sasha Bauer, Megan Bell, Kennedy Borle, Prescilla Carrion, Mylynda Massart, Christine Munro, Jehannine (J9) Austin   +8 more
wiley   +1 more source

Mavacamten Cardiac Myosin Inhibitor: Clinical Applications and Future Perspectives. [PDF]

Cureus
Ramadan MM, Al-Najjar RA, Abady RS, Obaid HA, Mostafa YA, Al-Obeid MT, Elmahal M.   +6 more
europepmc   +1 more source

Cardiac biomarkers in cats [PDF]

Borgeat, K A, Connolly, D J, Fuentes, V L   +2 more
core   +1 more source

The future of electronic health record‐based research: Leveraging informatics in genetic counseling research

Journal of Genetic Counseling, Volume 34, Issue 3, June 2025.
Abstract As health care embraces learning health systems, data‐oriented approaches provide a path for genetic counselors to actively contribute to improving clinical care through evidence‐driven insights. The informatics‐driven querying of electronic health record (EHR) data in genetic counseling has the potential to advance clinical practice, quality ...
Samantha E. Greenberg, Brian Reys, Heather Fisher, Mujeeb Basit   +3 more
wiley   +1 more source