Results 51 to 60 of about 7,955,722 (163)

The Effect of High-Dose Vitamin C on Biochemical Markers of Myocardial Injury in Coronary Artery Bypass Surgery [PDF]

Brazilian Journal of Cardiovascular Surgery, 2019
Objective: To evaluate the effect of high-dose vitamin C on cardiac reperfusion injury and plasma levels of creatine kinase-muscle/brain (CK-MB), troponin I, and lactate dehydrogenase (LDH) in patients undergoing coronary artery bypass grafting (CABG ...
Nafiseh Emadi, Mohammad Hasan Nemati, Mohammad Ghorbani, Elahe Allahyari   +3 more
doaj   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Rescue Balloon Pulmonary Angioplasty Prior to Pulmonary Endarterectomy With Concomitant Mitral Valve Plasty in High‐Risk Operable CTEPH

Pulmonary Circulation, Volume 16, Issue 2, April 2026.
ABSTRACT Pulmonary endarterectomy (PEA) is a potentially curative treatment for chronic thromboembolic pulmonary hypertension (CTEPH); however, decompensated right heart failure and concomitant cardiac procedures increase the risk of postoperative mortality. We report a case of operable CTEPH with severe mitral regurgitation causing right heart failure
Keiichi Ishida, Nobutaka Ikeda, Seiichiro Sakao, Koichiro Sugimura, Ryuki Yamada, Norihisa Yuge, Susumu Manabe   +6 more
wiley   +1 more source

Trimetazidina como aditivo em solução cardioplégica sem pré-tratamento não traz proteção adicional ao miocárdio isquêmico: estudo em modelo suíno de coração isolado Trimetazidine as cardioplegia addictive without pre-treatment does not improve myocardial protection: study in a swine working heart model

Brazilian Journal of Cardiovascular Surgery, 2008
OBJETIVO: Verificar, em modelo experimental de coração isolado de suínos, se a associação da trimetazidina à solução cardioplégica promove melhora no desempenho do coração.
Lindemberg da Mota Silveira Filho, Orlando Petrucci Jr, Marcio Roberto do Carmo, Pedro Paulo Martins de Oliveira, Karlos Alexandre Sousa Vilarinho, Reinaldo Wilson Vieira, Domingo Marcolino Braile   +6 more
doaj   +1 more source

Mitochondrial Ca2+ overload is a pivotal risk factor for lethal ventricular arrhythmias due to the oxidation of mitochondrial respirasome and energetic failure

British Journal of Pharmacology, Volume 183, Issue 7, Page 1404-1426, April 2026.
The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Background and Purpose Ventricular arrhythmias are a leading cause of death among patients with cardiovascular diseases and are associated with elevated ...
Felipe de Jesús Salazar‐Ramírez, Luis Alberto Luévano‐Martínez, Abraham Méndez‐Fernández, Judith Bernal‐Ramírez, Carolina A. Morales‐Ochoa, Christian Silva‐Platas, Alfredo Cabrera‐Orefice, Ana C. Murrieta, José Luis Velasco‐Bolom, Gricelda Mendiola‐Garza, Flavio Contreras‐Torres, Guillermo Torre‐Amione, Ernesto A. Aiello, Gerardo García‐Rivas   +13 more
wiley   +1 more source

Metabolomic Signatures Influenced by Different Cardioplegic Solutions in Cardiac Surgery

Journal of the Practice of Cardiovascular Sciences
Introduction: Cardioplegia is crucial for myocardial protection during cardiac surgery. However, the impact of different cardioplegia formulations on patients’ metabolomic responses has not been explored.
Chananya Karunasumetta, Chotika Chatgasem, Suriya Punchai, Kittisak Sawanyawisuth   +3 more
doaj   +1 more source

A Rare Case of Anterior Papillary Muscle Rupture Following Acute Non‐ST Elevation Myocardial Infarction

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Sudden hemodynamic deterioration after myocardial infarction should prompt immediate evaluation for papillary muscle rupture, even in the absence of a murmur or large‐vessel occlusion. Acute severe mitral regurgitation from papillary muscle rupture may mimic recurrent ischemia, and early echocardiography with prompt surgical intervention can ...
Biyas Thapa, Somee Rauniyar, Pratiksha Paudel   +2 more
wiley   +1 more source

Evaluation of Myocardial Protection in Prolonged Aortic Cross-Clamp Times: Del Nido and HTK Cardioplegia in Adult Cardiac Surgery

Medicina
Background and Objectives: Effective myocardial protection is essential for successful cardiac surgery outcomes, especially in complex and prolonged procedures.
Murat Yücel, Emre Demir Benli, Kemal Eşref Erdoğan, Muhammet Fethi Sağlam, Gökay Deniz, Hakan Çomaklı, Emrah Uğuz   +6 more
doaj   +1 more source

2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2016
Context: 2,3-Butanedione monoxime (BDM), an uncoupler of cardiac contraction, is commonly used in enzymatic dissociations to prevent hypercontraction of cardiomyocytes and in cardioplegic solutions to decrease oxygen demand during surgery.
Julio Alvarez-Collazo, Ana Iris López-Medina, Loipa Galán-Martínez, Julio L. Alvarez   +3 more
doaj  

The behavior of Troponin I and CKMB mass in children who underwent surgical correction of congenital heart malformations Comportamento da troponina I e CK-MB massa em crianças submetidas a correção cirúrgica das cardiopatias congênitas

Brazilian Journal of Cardiovascular Surgery, 2003
OBJECTIVE: To analyze the behavior of troponin (TROP I) and CKMB mass (CKMBm) in regards to the addition of magnesium in cardioplegic solutions; and also the influence of per-operative factors.
Pedro Rafael Salerno, Fabio Biscegli Jatene, Patrícia Elias Figueiredo, Ieda Jatene Bosisio, Marcelo Biscegli Jatene, Magaly Arraes dos Santos, Luís Carlos Bento de Souza, Adib Domingos Jatene   +7 more
doaj   +1 more source