Results 61 to 70 of about 7,955,722 (163)

RNA‐Binding Proteins and Ferroptosis in Cancer: Mechanism and Therapeutic Implications

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ferroptosis critically influences cancer cell fate and represents a promising therapeutic strategy. Emerging evidence identifies RNA‐binding proteins (RBPs) as key post‐transcriptional regulators of ferroptosis. The figure summarizes ferroptosis‐related RBPs across cancers: blue RBPs act as tumor suppressors by promoting ferroptosis, whereas red RBPs ...
Linlin Chang, Bin Lu, Haotian Shang, Wanjing Ding, Chunhua Wei, Xiaotian Qi, Pengxing He   +6 more
wiley   +1 more source

Deep learning‐enhanced 3D imaging unveils semaglutide impact on cardiac fibrosis

British Journal of Pharmacology, Volume 183, Issue 5, Page 1030-1047, March 2026.
Background and Purpose Myocardial fibrosis (MF), a hallmark of structural cardiac remodelling, drives disease progression across most forms of heart failure and plays a central role in heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, effective treatments remain scarce.
Sheyla Barrado‐Ballestero, Sarah Torp Yttergren, Max Hahn, Marie Biviano Rosenkilde, Ditte Marie Jensen, Michael Christensen, Louise Thisted, Heidi Lindgreen Holmberg, Geoffrey Teixeira, Tor Biering‐Sørensen, Casper Gravesen Salinas, Urmas Roostalu   +11 more
wiley   +1 more source

Ação da cardioplegia na proteção miocárdica: estudo experimental através das réplicas de criofraturas The cardioplegic action in the myocardial protection: experimental study through freeze fraction replictions

Brazilian Journal of Cardiovascular Surgery, 1987
Foi avaliado, experimentalmente, o grau de proteção miocárdica oferecido por soluções cardioplégicas e hipotermia, à anóxia induzida pela interrupção do fluxo sangüíneo coronário em 20 cães. A isquemia miocárdica foi obtida através do pinçamento da aorta
Luis Alberto Dallan, Sérgio Almeida de Oliveira, Lurdes Higuchi, Edgard A Lopes, Antônio Sesso, Geraldo Verginelli, Adib D Jatene   +6 more
doaj  

Nonvalvular Papillary Fibroelastoma of the Left Ventricle: A Case Report and Review of the Literature

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Papillary fibroelastoma (PFE) is a benign primary cardiac tumor that most commonly arises from valvular endocardium, whereas nonvalvular involvement, particularly within the left ventricle, is rare. Despite benign histology, PFEs are clinically relevant due to mobility and embolic risk.
Aibek E. Mirrakhimov, Satabdi Datta Choudhury   +1 more
wiley   +1 more source

Contained Rupture of a Saphenous Vein Graft Pseudoaneurysm Following Coronary Artery Bypass Grafting

Case Reports in Cardiology, Volume 2026, Issue 1, 2026.
Saphenous vein graft (SVG) pseudoaneurysms are a rare cause of late graft failure with potentially lethal consequences if left untreated. We present the case of a patient who underwent multivessel coronary artery bypass grafting more than 10 years earlier and presented with chest pain.
Harry Ramcharran, Mahbub Jamil, Joseph Petro, Zhandong Zhou, Satabdi Datta Choudhury   +4 more
wiley   +1 more source

Evaluating the Efficacy and Outcomes of Transcatheter Aortic Valve Replacement Versus Surgical Aortic Valve Replacement in Low‐ to Intermediate‐Risk Aortic Regurgitation Patients: A Comprehensive Clinical Comparison

Cardiology Research and Practice, Volume 2026, Issue 1, 2026.
Background Transcatheter aortic valve replacement (TAVR) has been established as an alternative to surgery for high‐risk aortic regurgitation (AR) patients. However, its applicability to low‐ and intermediate‐risk populations remains under investigation.
Xiaoxue Zhang, Chenxi Yan, Shiliang Li, Cai Cheng, Esha Saini   +4 more
wiley   +1 more source

Comparison of Enoximone, Amrinone, or Levosimendan Enriched St. Thomas’ Hospital Cardioplegic Solutions Used for Myocardial Preservation in Isolated Guinea Pig Hearts

Acta Medica, 2002
Myocardial contractile function after cardioplegic arrest is often depressed and an ideal cardioplegic solution has not been developed yet. The aim of this study was to assess the efficacy of phosphodiesterase III inhibitors, amrinone and enoximone, and ...
Cengiz Köksal, Öner Süzer, A Kürsat Bozkurt, Sebahat Köseoğlu   +3 more
doaj   +1 more source

Enhanced myocardial protection in failing hearts: comparative outcomes of single-dose Del Nido and conventional blood cardioplegia in emergency low-ejection fraction coronary artery bypass grafting (CABG)

Medicinski Glasnik
  Abstract   Background: Optimal myocardial protection remains challenging in emergency coronary revascularization, especially in patients with severely reduced left ventricular function.
emced Khalil
doaj   +1 more source

Solução cardioplégica sangüínea versus acelular: avaliação hemodinâmica através de estudo experimental em cães Hemodynamic evaluation of myocardial protection by blood and acellular cardioplegic solutions: an experimental study

Brazilian Journal of Cardiovascular Surgery, 1990
Estudo experimental em 20 cães permitiu avaliar hemodinamicamente o grau de proteção miocárdica à anóxia, através do emprego de solução cardioplégica sangüínea e acelular.
Luís Alberto Dallan, Sérgio Almeida de Oliveira, José Carlos R Iglézias, Paulo M Pêgo-Fernandes, José Otávio C Auler Júnior, Geraldo Verginelli, Adib D Jatene   +6 more
doaj  

Comparison of Cardioplegic Solutions in Coronary Bypass Surgery Over Autophagy and Apoptosis Mechanisms. [PDF]

Arq Bras Cardiol, 2023
Sener EF, Hamurcu Z, Taheri S, Tahtasakal R, Delibasi N, Elcik D, Mehmetbeyoglu E, Tuncay A, Dal F, Bayram KK, Gunes I, Emirogullari ON.   +11 more
europepmc   +1 more source