Results 61 to 70 of about 1,491 (172)

2,3-Butanedione monoxime attenuates the β-adrenergic response of the L-type Ca2+ current in rat ventricular cardiomyocytes [PDF]

open access: yesJournal of Pharmacy & Pharmacognosy Research, 2016
Context: 2,3-Butanedione monoxime (BDM), an uncoupler of cardiac contraction, is commonly used in enzymatic dissociations to prevent hypercontraction of cardiomyocytes and in cardioplegic solutions to decrease oxygen demand during surgery.
Julio Alvarez-Collazo   +3 more
doaj  

The behavior of Troponin I and CKMB mass in children who underwent surgical correction of congenital heart malformations Comportamento da troponina I e CK-MB massa em crianças submetidas a correção cirúrgica das cardiopatias congênitas

open access: yesBrazilian Journal of Cardiovascular Surgery, 2003
OBJECTIVE: To analyze the behavior of troponin (TROP I) and CKMB mass (CKMBm) in regards to the addition of magnesium in cardioplegic solutions; and also the influence of per-operative factors.
Pedro Rafael Salerno   +7 more
doaj   +1 more source

The Transaxillary Access for Minimally Invasive Valve Surgery Is Safe and Effective in Selected Patients With Native Valve Endocarditis

open access: yesJournal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Objectives Minimally invasive surgery for endocarditis reflects an emerging advancement in surgical therapy. Transaxillary access is a novel approach, with little current data on its safety and efficacy in these patients. This study reports outcomes of a transaxillary access cohort in aortic and mitral endocarditis compared to a full‐sternotomy cohort.
Asen Petrov   +9 more
wiley   +1 more source

Ventricular Reverse Remodeling After Coronary Artery Bypass, Chordal‐Sparing Mitral Valve Replacement, and Tricuspid Valve Repair

open access: yesJournal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Objective This study aimed to evaluate the long‐term efficacy of a standardized triple procedure—coronary artery bypass grafting (CABG), chordal‐sparing mitral valve replacement, and tricuspid annuloplasty—in high‐risk patients with end‐stage ischemic dilated cardiomyopathy (IsDCM) for whom heart transplantation was not an option.
Živojin S. Jonjev   +6 more
wiley   +1 more source

Ação da cardioplegia na proteção miocárdica: estudo experimental através das réplicas de criofraturas The cardioplegic action in the myocardial protection: experimental study through freeze fraction replictions

open access: yesBrazilian Journal of Cardiovascular Surgery, 1987
Foi avaliado, experimentalmente, o grau de proteção miocárdica oferecido por soluções cardioplégicas e hipotermia, à anóxia induzida pela interrupção do fluxo sangüíneo coronário em 20 cães. A isquemia miocárdica foi obtida através do pinçamento da aorta
Luis Alberto Dallan   +6 more
doaj  

Outcomes of Open Transcatheter Aortic Valve Implantation in the Mitral Position for Severe Mitral Annular Calcification: A Multicentre Experience

open access: yesJournal of Cardiac Surgery, Volume 2026, Issue 1, 2026.
Introduction Mitral annular calcification (MAC) presents a significant surgical challenge, often rendering conventional surgery high risk. The presence of a heavily calcified, rigid, and friable annulus significantly increases the risk of complications such as atrioventricular groove disruption, annular rupture, and paravalvular leak.
Laith Kayyal   +9 more
wiley   +1 more source

Cardiothoracic Surgery for a Giant Pericardial Cyst: When Nature's Precision Leads to Surgical Complexity

open access: yesClinical Case Reports, Volume 13, Issue 12, December 2025.
ABSTRACT A giant pericardial cyst, though typically benign, can present with significant symptoms due to its compressive effects on cardiac structures. Accurate imaging and prompt surgical intervention are crucial for diagnosis and treatment, highlighting the importance of recognizing this rare condition in patients with unexplained cardiopulmonary ...
Romana Riyaz   +2 more
wiley   +1 more source

Four decades of heart–lung transplantation: Milestones and outcomes in advanced cardiorespiratory failure

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 3899-3909, December 2025.
Abstract Aims Heart–lung transplantation (HLTx) remains a life‐saving intervention for patients with end‐stage cardiopulmonary failure. We retrospectively analysed long‐term HLTx outcomes at our centre to assess survival trends and evaluate the impact of evolving immunosuppressive, surgical and perioperative strategies.
L. Lily Rosenthal   +10 more
wiley   +1 more source

Comparison of Enoximone, Amrinone, or Levosimendan Enriched St. Thomas’ Hospital Cardioplegic Solutions Used for Myocardial Preservation in Isolated Guinea Pig Hearts

open access: yesActa Medica, 2002
Myocardial contractile function after cardioplegic arrest is often depressed and an ideal cardioplegic solution has not been developed yet. The aim of this study was to assess the efficacy of phosphodiesterase III inhibitors, amrinone and enoximone, and ...
Cengiz Köksal   +3 more
doaj   +1 more source

Protective effects of neutrophil serine protease inhibition against ischemia–reperfusion injury in lung or heart transplantation

open access: yesThe FEBS Journal, Volume 292, Issue 22, Page 5877-5887, November 2025.
A major complication of organ transplantation is primary graft dysfunction, which represents the leading cause of early post‐transplantation morbidity and mortality. Pre‐operative depletion of neutrophil serine proteases in circulating neutrophils by pretreatment with a cathepsin C inhibitor in recipients could prevent early post‐operative ...
Sevil Korkmaz‐Icöz   +6 more
wiley   +1 more source

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