Results 21 to 30 of about 140 (69)

Enrichment analysis of functional groups within the stem cell-derived cardiopoietic transcriptome

, 2011
Approximately half of all expression profiles in cardiopoietic cells are downregulated while a third do not change more than 1.5-fold compared to unstimulated embryonic stem cells. Upregulated genes account for >10% of all genes.
Randolph S Faustino (48222), Carmen Perez-Terzic (48224), Atta Behfar (48223), Andre Terzic (48225)   +3 more
core   +1 more source

Nodal network anchors orchestrate coordinated recruitment of specialized ontological classes to secure a developmental theme

, 2011
Left: a five group K-means algorithm, 4 × 6 SOM, and QT filter were each used to independently dissect the transcriptome of embryonic stem cell (ES) derived cardiogenesis.
Randolph S Faustino (48222), Carmen Perez-Terzic (48224), Atta Behfar (48223), Andre Terzic (48225)   +3 more
core   +1 more source

Phenotypic changes and transcriptome dynamism during cardiac stem cell differentiation

, 2011
Electron microscopy visualized morphological changes occurring during guided stem cell cardiogenesis (left column) with associated expression and distribution of the selected cardiac transcription factor MEF2C and the cardiac contractile protein α ...
Randolph S Faustino (48222), Carmen Perez-Terzic (48224), Atta Behfar (48223), Andre Terzic (48225)   +3 more
core   +1 more source

Optimized Catheter System Demonstrates Utility for Endomyocardial Delivery of Cardiopoietic Stem Cells in Target Patients With Heart Failure. [PDF]

Tex Heart Inst J, 2023
Bartunek J, Terzic A.
europepmc   +1 more source

Hhex and cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells

, 2014
Cardiac muscle differentiation in vivo is guided by sequential growth factor signals, including endoderm-derived diffusible factors, impinging on cardiogenic genes in the developing mesoderm.
Liu, Y, Tolmachov, O, Barahona, M, Minchiotti, G, Schneider, MD, Kaneda, R, Subkhankulova, T, Schwartz, RJ, Leja, TW, ,   +9 more
core  

The Development of a Chemical Biology Pipeline for the Identification of Small Molecules that Induce Cardiopoiesis in Murine Embryonic Stem Cells [PDF]

, 2012
High-Content Screening (HCS) is a form of high throughput screening (HTS) that couples automated microscopy with high throughput image analysis to quantify biological effects. Thus, it can be thought of as applied biology bridging basic bench research to
Bushway, Paul Jay
core  

Cardiopoietic cell therapy for advanced ischemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled chart-1 clinical trial

, 2018
Aims Cardiopoietic cells, produced through cardiogenic conditioning of patients\u27 mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure Cardiopoietic Regenerative Therapy (CHART-1) trial aimed to validate cardiopoiesis ...
Beleslin, Branko, Horvath, Ivan G., Filippatos, Gerasimos S., Terzic, Andre, Musialek, Piotr, Katz, Amos, Jagic, Nikola, Vanderheyden, Marc, Davison, Beth A., Seferovic, Petar M., Radovanovic, Slavica, Obradovic, Slobodan, Bartunek, Jozef, Dolatabadi, Dariouch, Arandjelovic, Aleksandra, Andreka, Peter, Merkely, Bela, Wojakowski, Wojciech, Edes, Istvan, El Nakadi, Badih   +19 more
core  

Proteomic Analysis of Exosomes during Cardiogenic Differentiation of Human Pluripotent Stem Cells. [PDF]

Cells, 2021
Ashok P, Tzanakakis ES.
europepmc   +1 more source

Analysing electrocardiographic traits and predicting cardiac risk in UK biobank. [PDF]

JRSM Cardiovasc Dis, 2021
Ramírez J, van Duijvenboden S, Young WJ, Orini M, Jones AR, Lambiase PD, Munroe PB, Tinker A.   +7 more
europepmc   +1 more source

Cardiopoietic stem cell therapy restores infarction-altered cardiac proteome. [PDF]

NPJ Regen Med, 2020
Arrell DK, Rosenow CS, Yamada S, Behfar A, Terzic A.   +4 more
europepmc   +1 more source