Results 171 to 180 of about 20,955 (188)

Cardioprotective growth factors

Cardiovascular Research, 2009
Many of the originally identified cardiovascular 'growth factors' have been demonstrated to exert a diverse variety of actions within the cardiovascular system, the majority of which are unrelated to their initially proposed mechanism of action. Interestingly, several of these growth factors have been demonstrated to protect the cardiomyocyte from the ...
Derek J, Hausenloy, Derek M, Yellon
openaire   +2 more sources

Sildenafil and Cardioprotection

Current Pharmaceutical Design, 2013
The phosphodiesterese-5 (PDE5) inhibitors, including sildenafil (Viagra™), vardenafil (Levitra™), tadalafil (Cialis™) and avanafil (Stendra™) have been developed for the treatment of erectile dysfunction. Moreover, sildenafil and tadalafil have been approved for the management of pulmonary arterial hypertension.
openaire   +2 more sources

Antioxidants and Cardioprotection

Medicine & Science in Sports & Exercise, 2007
Limiting myocardial ischemia-reperfusion (IR) injury is essential for preventing contractile dysfunction and limiting morbidity and mortality associated with ischemic heart disease. Over the last few decades, it has become clear that during IR insults, myocardial oxygen radical formation is accelerated and plays a critical role in mediating cellular ...
openaire   +2 more sources

Prolylcarboxypeptidase: A cardioprotective enzyme

The International Journal of Biochemistry & Cell Biology, 2009
Prolylcarboxypeptidase (PRCP) is involved in regulating the blood flow through active tissues in order to preserve the internal environment. The expression of PRCP in tissues is determined by a number of pharmacological stimuli such as glucocorticoids and a combination of dexamethasone plus the mu-opioid receptor agonist [D-Ala2, N-Me-Phe4, Gly5-ol ...
J, Mallela, J, Yang, Z, Shariat-Madar
openaire   +2 more sources

Inhalational Anaesthetics and Cardioprotection

2008
The heart has a strong endogenous cardioprotection mechanism that can be triggered by short periods of ischaemia (like during angina) and protects the myocardium during a subsequent ischaemic event (like during a myocardial infarction). This important mechanism, called ischaemic pre-conditioning, has been extensively investigated, but the practical ...
Weber, N. C., Schlack, W.
openaire   +3 more sources

Acquired and innate cardioprotection

Journal of Applied Physiology, 2007
with aging of the population, cardiovascular disease is the leading cause of death, disability, and morbidity across continents. In a series of mini-reviews, the Journal of Applied Physiology highlights the most recent advances in molecular and integrative physiology that have provided new ...
Andre, Terzic, Russell L, Moore, Scott A, Waldman   +2 more
openaire   +2 more sources

Phytoestrogens as Cardioprotective Agents

Cardiology in Review, 2005
Epidemiologic studies have shown that women with a higher dietary intake of phytoestrogens, plant-derived compounds with partial estrogen agonist properties, have a lower incidence of cardiovascular disease and breast and uterine cancer than women with a lower dietary intake of these substances.
Denise, Park, Tiffany, Huang, William H, Frishman   +2 more
openaire   +2 more sources

Natural Polyphenols and Cardioprotection

Mini Reviews in Medicinal Chemistry, 2011
With more than 8000 polyphenols found in food (mainly, wine, tea, coffee, cocoa, vegetables and cereals), many epidemiological studies suggest that the intake of polyphenol-rich foods has a beneficial effect on a large number of cardiovascular risk factors, such as high blood pressure, high blood cholesterol, obesity, diabetes and smoking.
S, Lecour, K T, Lamont
openaire   +2 more sources

Cardioprotective drugs

2015
Cardioprotective drugs are important in the treatment of patients at risk for or with documented cardiovascular disease. Beta-blockers are indicated after acute coronary syndromes, stable coronary artery disease, heart failure, and arrhythmias. Angiotensin-converting enzyme inhibitors (ACEi) are important in congestive heart failure, stable angina ...
Johan De Sutter, Miguel Mendes, Oscar H. Franco   +2 more
openaire   +1 more source

Cardioprotection in anesthesia.

Minerva anestesiologica, 2008
Ischemic heart disease is the major cause of morbidity and mortality in the Western world. With the advancing age of the surgical population, anesthesiologists increasingly have to treat patients with known or suspected ischemic heart disease in the perioperative period.
openaire   +2 more sources