Results 21 to 30 of about 290 (164)

[Retracted] Grading Evaluation of Cardiotoxicity in Patients with Breast Cancer Treated with Adjuvant Paclitaxel Anthracycline/Cyclophosphamide Chemotherapy: A Meta‐Analysis

Computational and Mathematical Methods in Medicine, Volume 2022, Issue 1, 2022., 2022
Objective. The cardiac safety of concurrent treatment with anthracycline (A), cyclophosphamide (C), and paclitaxel (T) in an adjuvant BC treatment regimen is still under debate. In this study, we aimed to determine cardiotoxicity events following ACT chemotherapy among operable breast cancer patients without HER2‐positive. Methods.
Weibao Hu, Mengli Song, Linfeng Li, Ahmed Faeq Hussein   +3 more
wiley   +1 more source

Integrated Bioinformatics and Clinical Correlation Analysis of Key Genes, Pathways, and Potential Therapeutic Agents Related to Diabetic Nephropathy

Disease Markers, Volume 2022, Issue 1, 2022., 2022
Background. Diabetic nephropathy (DN) is a common microvascular complication of diabetes and a major cause of end‐stage renal disease, resulting in a substantial socioeconomic burden around the world. Some unknown biomarkers, mechanisms, and potential novel agents regarding DN are yet to be identified. Methods.
Shengnan Chen, Lei Chen, Hongli Jiang, Changli Zhou   +3 more
wiley   +1 more source

Novel Molecular Targets Participating in Myocardial Ischemia-Reperfusion Injury and Cardioprotection. [PDF]

Cardiol Res Pract, 2019
Worldwide morbidity and mortality from acute myocardial infarction (AMI) and related heart failure remain high. While effective early reperfusion of the criminal coronary artery after a confirmed AMI is the typical treatment at present, collateral myocardial ischemia‐reperfusion injury (MIRI) and pertinent cardioprotection are still challenging to ...
Liu NB, Wu M, Chen C, Fujino M, Huang JS, Zhu P, Li XK.   +6 more
europepmc   +2 more sources

Mitochondrial biogenesis: An update

Journal of Cellular and Molecular Medicine, Volume 24, Issue 9, Page 4892-4899, May 2020., 2020
Abstract In response to the energy demand triggered by developmental signals and environmental stressors, the cells launch the mitochondrial biogenesis process. This is a self‐renewal route, by which new mitochondria are generated from the ones already existing.
Lucia‐Doina Popov
wiley   +1 more source

Effect of pretreatment with omega-3 polyunsaturated fatty acids (PUFAs) on hematological parameters and platelets aggregation in patients during elective coronary artery bypass grafting [PDF]

, 2013
Bacground/Aim. Using omega-3 polyunsaturated fatty acids (PUFAs) in coronary artery bypass graft surgery (CABG) could provide protection against ischemicreperfusion damage, prevention of postoperative arrhythmia and attenuation of inflammatory ...
Antunović Mirjana, Jevđić Jasna, Mihajlović Ivana, Popadić Ana, Subota Vesna, Udovičić Ivo, Veljović Milić, Vulović Tatjana   +7 more
core   +1 more source

Розроблення нових активаторів АТФ-чутливих калієвих каналів клітинних мембран [PDF]

, 2016
Розроблено дві інноваційні бібліотеки (413 сполук на циклосульфамідиновому ядрі та 709 сполук на ортопіримідинсульфамідиновому ядрі) нових потенційних відкривачів АТФ-чутливих калієвих каналів клітинних мембран.
Бойко, О.М., Васильченко, О.В., Досенко, В.Є., Кришталь, О.О., Максимюк, О.П., Платонов, М.О., Струтинська, Н.А., Струтинський, Р.Б., Федянович, І.М.   +8 more
core   +1 more source

Pharmacological correction of intrarenal hemodynamic disorders in acute kidney injury (part 2) [PDF]

, 2018
Evaluate the possibilities of individual pharmacological correction and intensive care of patients with acute kidney injury of different origin. A prospective nonrandomized study.
Gorodnik, Georgiy A., Grigorenko, Aleksandr P., Kuznetsova, Irina V., Potapov, Vladimir V., Shano, Valentina P., Shramenko, Katherine K.   +5 more
core   +2 more sources

Potential Therapeutic Role of Purinergic Receptors in Cardiovascular Disease Mediated by SARS‐CoV‐2

Journal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
Novel coronavirus disease 2019 (COVID‐19) causes pulmonary and cardiovascular disorders and has become a worldwide emergency. Myocardial injury can be caused by direct or indirect damage, particularly mediated by a cytokine storm, a disordered immune response that can cause myocarditis, abnormal coagulation, arrhythmia, acute coronary syndrome, and ...
Fernanda dos Anjos, Júlia Leão Batista Simões, Charles Elias Assmann, Fabiano Barbosa Carvalho, Margarete Dulce Bagatini, Ravirajsinh Jadeja   +5 more
wiley   +1 more source

Розробка методик кількісного визначення субстанції кардіазол з використанням високоефективної рідинної хроматографії [PDF]

, 2019
The aim. Development of methods of quantitative determination of Cardiazol substance using high-performance liquid chromatography.Materials and methods.
Bezruk, Ivan, Drapak, Iryna, Harna, Svitlana, Ivanauskas, Liudas, Perekhoda, Lina, Zimenkovsky, Borys   +5 more
core   +5 more sources

Nitrogen compounds prevent H9c2 myoblast oxidative stress-induced mitochondrial dysfunction and cell death [PDF]

, 2010
Oxidative stress has been connected to various forms of cardiovascular diseases. Previously, we have been investigating the potential of new nitrogen-containing synthetic compounds using a neuronal cell model and different oxidative stress conditions
Coutinho, O. P., Oliveira, Paulo J., Sardão, V. A., Silva, João P.   +3 more
core   +1 more source