Results 31 to 40 of about 192 (165)
¿Son los estrógenos transdérmicos cardioprotectores?
Revista médica de Chile, 2001 Transdermic estrogens share many of the oral estrogens cardiovascular effects, but so far there are no studies proving that they have a cardioprotective effect neither in animals nor in human beings. The doubt is outlined moreover, when most of the investigations performed with oral estrogens in animals show an antiatherogenic effect, while the few ...
Blümel M, Juan E, Campodónico G, Italo
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Cardioprotector effect of Phosphodiesterase 5 inhibitors in experimental model for Diabetes Mellitus
ABCS Health Sciences, 2021 Diabetes mellitus (DM) is considered a 21st century pandemic and is often associated with cardiovascular disease (CVD). The aim of this integrative review was to analyze the cardioprotective effects of phosdodiesterase-5 (PDE5i) inhibitors in experimental diabetes models. The articles were selected from the PubMed, SciElo and LILACS databases from 2014
Gilson Nogueira Freitas +1 more
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The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro [PDF]
British Journal of Cancer, 2003 Besides its cardiotoxic effect, doxorubicin also elicits inflammatory effects in vivo. 7-Monohydroxyethylrutoside (monoHER) has recently been used as a protector against doxorubicin-induced cardiotoxicity in vivo. It is not known yet whether monoHER can also protect against doxorubicin-induced inflammatory effects.
Abou el Hassan, M.A. +6 more
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Plant Sources, Extraction Methods, and Uses of Squalene
International Journal of Agronomy, Volume 2018, Issue 1, 2018., 2018 Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the blood, prevents the suffering of cardiovascular ...
M. Azalia Lozano-Grande +5 more
wiley +1 more source
Growth hormone-releasing peptides and the heart: secretagogues or cardioprotectors? [PDF]
Cardiovascular Research, 2004 See article by Iwase et al. [13] in this issue. Growth hormone (GH) and insulin-like growth factor-1 (IGF-1) are multifunctional hormones with potent cardiotropic effects in prenatal and postnatal cardiac development. Evidence from animal and clinical studies has documented the beneficial effects of the GH-IGF-1 axis on cardiac hypertrophy and ...
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Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy
International Journal of Endocrinology, Volume 2018, Issue 1, 2018., 2018 Diabetic nephropathy (DN) is the second most frequent and prevalent complication of diabetes mellitus (DM). The increase in the production of oxidative stress (OS) is induced by the persistent hyperglycemic state capable of producing oxidative damage to the macromolecules (lipids, carbohydrates, proteins, and nucleic acids). OS favors the production of
Sonia Sifuentes-Franco +4 more
wiley +1 more source
Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14‐3‐3η
Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018 Gastrodin (GAS) is the major component isolated from the rhizome of the Chinese traditional medicinal herb “Tianma.” Many clinical studies have found that GAS protects cardiomyocytes in cardiovascular diseases, although the effects and underlying mechanisms on cardiovascular anoxia/reoxygenation (A/R) injury remain unknown.
Meifang Zhu +6 more
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Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018 Grape pomace is a potential source of natural antioxidant agents. Phenolic compounds and antioxidant and cardioprotective properties of fresh and fermented pomace extracts obtained from Vitis vinifera L. red variety Fetească neagră grown in Romania in 2015 were investigated. Grape pomace extracts total phenolic index, total tannins, total anthocyanins,
Ştefania Silvia Balea +5 more
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Oxidative Medicine and Cellular Longevity, Volume 2017, Issue 1, 2017., 2017 Aims. The study was designed to explore whether hydrogen sulphide (H2S) and nitric oxide (NO) generation changed in D‐galactose‐ (D‐gal‐) induced ageing, the possible effects of exogenous H2S supplementation, and related mechanisms. Results. In D‐gal‐induced senescent mice, both H2S and NO levels in the heart, liver, and kidney tissues were decreased ...
Wei Wu +7 more
wiley +1 more source
Clinical and Experimental Immunology, 2003 SUMMARYThe present study investigates the immunological effects of a combination treatment of mitoxantrone and the cardioprotector dexrazoxane in experimental autoimmune encephalomyelitis (EAE). Mitoxantrone, an anthracycline-derived immunosuppressive drug has been approved recently for treatment of very active multiple sclerosis (MS).
F X, Weilbach +3 more
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