Results 41 to 50 of about 192 (165)

Differential Role of Adipose Tissues in Obesity and Related Metabolic and Vascular Complications

International Journal of Endocrinology, Volume 2016, Issue 1, 2016., 2016
This review focuses on the contribution of white, brown, and perivascular adipose tissues to the pathophysiology of obesity and its associated metabolic and vascular complications. Weight gain in obesity generates excess of fat, usually visceral fat, and activates the inflammatory response in the adipocytes and then in other tissues such as liver ...
Almudena Gómez-Hernández, Nuria Beneit, Sabela Díaz-Castroverde, Óscar Escribano, Kristin Eckardt   +4 more
wiley   +1 more source

Fenofibrate plus Metformin Produces Cardioprotection in a Type 2 Diabetes and Acute Myocardial Infarction Model

PPAR Research, Volume 2016, Issue 1, 2016., 2016
We investigated whether fenofibrate, metformin, and their combination generate cardioprotection in a rat model of type 2 diabetes (T2D) and acute myocardial infarction (AMI). Streptozotocin‐induced diabetic‐ (DB‐) rats received 14 days of either vehicle, fenofibrate, metformin, or their combination and immediately after underwent myocardial ischemia ...
Víctor Hugo Oidor-Chan, Enrique Hong, Francisca Pérez-Severiano, Sergio Montes, Juan Carlos Torres-Narváez, Leonardo del Valle-Mondragón, Gustavo Pastelín-Hernández, Alicia Sánchez-Mendoza, Yanbo Fan   +8 more
wiley   +1 more source

Pre‐Conditioning with CDP‐Choline Attenuates Oxidative Stress‐Induced Cardiac Myocyte Death in a Hypoxia/Reperfusion Model

The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014
Background. CDP‐choline is a key intermediate in the biosynthesis of phosphatidylcholine, which is an essential component of cellular membranes, and a cell signalling mediator. CDP‐choline has been used for the treatment of cerebral ischaemia, showing beneficial effects.
Héctor González-Pacheco, Aurelio Méndez-Domínguez, Salomón Hernández, Rebeca López-Marure, Maria J. Vazquez-Mellado, Cecilia Aguilar, Leticia Rocha-Zavaleta, M. Karmazyn, R. M. Mentzer   +8 more
wiley   +1 more source

The mRNA expression character of iNOS and eNOS in the rats myocardium with alcoholic cardiomyopathy during metabolitotropic cardioprotectors therapy

, 2017
В останній час у якості ще одного механізму ушкодження міокарду при алкоголізмі стали розглядати систему NO. У наш час майже відсутні роботи про характер експресії мРНК iNOS та еNOS в міокарді при алкогольній кардіоміопатії та медикаментозної корекції ...
Бєленічев, Ігор Федорович, Камишний, О. М., Kamyshnyi, O. M., Стеблюк, В. С., Камышный, А. М., Беленичев, Игорь Федорович, Stebliuk, V. S., Bielenichev, I. F.   +7 more
core   +1 more source

Фармакологічна профілактика перенапруження серцево-судинної системи як фактор збереження здоров'я спортсменів [PDF]

, 2017
Due to the worsening of WADA's requirements regarding myocardial protection and the prohibition of the most commonly used trimetasidine and meldonium in sport, new directions for the use of cardioprotectors are needed.
Гуніна, Л.
core  

Flavonoids as protectors against doxorubicin cardiotoxicity: Role of iron chelation, antioxidant activity and inhibition of carbonyl reductase

, 2007
Anthracycline antibiotics (e.g. doxorubicin and daunorubicin) are among the most effective and widely used anticancer drugs. Unfortunately, their clinical use is limited by the dose-dependent cardiotoxicity.
van der Vijgh, Wim J.F., Bast, Aalt, Kvasnièková, Eva, Kaiserová, Helena, Kvasničková, Eva, Simunek, T., Kaiserova, H., Šimůnek, Tomáš, van der Vijgh, W.J., Kvasnickova, E., Bast, A.   +10 more
core   +1 more source

Analysis of original bis-arylazaazkanes derivatives compliance with the calculated pharmacophoric models of biaromatic ligands of cardioprotective drugs biotargets

Фармакокинетика и Фармакодинамика
Eight important biotargets of biaromatic cardioprotective drugs were selected in this work: calcium Cav1.2-channel, sodium Nav1.5-channel, potassium hERG-channel and Kv1.5-channel, HCN-channel, β1-adrenergic receptor, ryanodine RyR2-receptor and σ1 ...
G. V. Mokrov, A. S. Pantileev, T. Yu. Vorobieva, V. E. Biryukova, S. A. Kryzhanovskii, V. L. Dorofeev   +5 more
doaj   +1 more source

ВИБІР РАЦІОНАЛЬНИХ ДОПОМІЖНИХ РЕЧОВИН ДЛЯ СТВОРЕННЯ ТАБЛЕТОК «АНГІОЛІН» МЕТОДОМ ВОЛОГОЇ ГРАНУЛЯЦІЇ

, 2016
Introduction.  Cardiovascular diseases along with cancer and diabetes firmly lead among the most common and most dangerous diseases of XX, and now the XXI century. Diseases of the cardiovascular system are numerous.
Kucherenko, L. I., Moryak, Z. B., Bіdnenko, O. S., Mazur, I. A.   +3 more
core   +1 more source

Assessment of continuous use of anesthetics agents on the myocardial function in swine model of cardiac arrest.

, 2021
Introdução: Disfunção miocárdica após uma parada cardíaca é um evento frequente e impõe grande morbimortalidade. Recentemente, agentes anestésicos têm sido descritos como cardioprotetores em estados de isquemia e reperfusão, sendo pouco estudados em ...
Brandão, Paulo Gabriel Melo
core   +1 more source

Strategy of non-drug management of metabolic syndrome, which is accompanied by prediabetes and hypertension

Mìžnarodnij Endokrinologìčnij Žurnal
Background. The condition of prediabetes implies the possibility to achieve stable normal glycemic indicators in order to prevent the further development of diabetes without using drug therapy.
G. Myhalchyshyn, J. Komisarenko, A. Kosinov   +2 more
doaj   +1 more source