Results 31 to 40 of about 290 (164)

¿Son los estrógenos transdérmicos cardioprotectores?

Revista médica de Chile, 2001
Transdermic estrogens share many of the oral estrogens cardiovascular effects, but so far there are no studies proving that they have a cardioprotective effect neither in animals nor in human beings. The doubt is outlined moreover, when most of the investigations performed with oral estrogens in animals show an antiatherogenic effect, while the few ...
Blümel M, Juan E, Campodónico G, Italo
openaire   +2 more sources

The effect of cardioprotectors on protease-іnhіbіtory potentіal in blood and heart of rats with epinephrine-induced myocardial ischemia

Regulatory Mechanisms in Biosystems, 2016
Coronary heart disease is one of the major causes of illness and of deaths in Europe, therefore the definition of the signaling pathways involved in cardioprotection represents a challenging goal in order to discover novel pharmacological approaches. One
V. Paronik, O. Shaul’s’ka, L. Diachenko, A. Shevtsova   +3 more
doaj   +1 more source

Status of rats myocardium under subchronic mercury exposure and its pharmacological correction [PDF]

, 2017
The article is devoted to the characteristics of the myocardium restructuring under the influence of 0.01 LD50 mercury (II) chloride, in rats, under subchronic exposure, and the correction of the detected changes.
Chaikovsky, B. Yuri, Chaikovsky, B. Yuri, Kaminsky , F. Rostislav, Kaminsky , F. Rostislav, Sokurenko, M. Liudmyla, Sokurenko, M. Liudmyla   +5 more
core   +2 more sources

ПРИМЕНЕНИЕ НИКОРАНДИЛА ПРИ СЕРДЕЧНО-СОСУДИСТЫХ ЗАБОЛЕВАНИЯХ И ОПТИМИЗАЦИЯ СХЕМ ЕГО НАЗНАЧЕНИЯ

Архивъ внутренней медицины, 2012
Nicorandil is a dual pharmacological mechanism anti-anginal agent with adenosinetriphosphat-esensitive potassium (Кatp) channel agonist and nitrate-like properties.
Ю. Б. Белоусов
doaj   +1 more source

SYNTHESIS AND DIURETIC ACTIVITY OF 2-(5-(PHENOXYMETHYL)-4-R1-1,2,4-TRIAZOLE-3-YLTHIO)ACETIC ACIDS AND THEIR SALTS

Zaporožskij Medicinskij Žurnal, 2014
It is known that drugs based on the 1,2,4-triazole have a wide spectrum of biological activities. They are effective cardioprotectors, hepatoprotectors, anti-oxidants, which are widely used in cardiology practice.
Yu. N. Kucheryavyi, A. G. Kaplaushenko, E. S. Pruhlo   +2 more
doaj   +1 more source

Yacton and mexicor influence on prooxidant-antioxidant homeostasis and protein synthesis in the myocardium of rats in conditions of doxorubicin cardiomyopathy

Zaporožskij Medicinskij Žurnal, 2015
Doxorubicin, which is included in the scheme of cancer treatment, possesses cardiotoxicity that requires effective cardioprotectors searching. Aim.
E. A. Raketskaya , I. S. Chekman, N. A. Gorchakova   +2 more
doaj   +1 more source

Age-dependent cardioprotective action of meldonium on heart remodeling under the experimental hypoosmolar hyperhydration [PDF]

, 2019
Комплексне лікування захворювань, які призводять до позитивного водного балансу, вимагає призначення кардіопротекторів. Метою нашого дослідження було визначення морфологічних змін серця щурів різного віку під впливом гіпоосмолярної гіпергідратації та ...
Bumeister, L., Bumeister, Valentyna Ivanivna, Demikhova, Nadiia Volodymyrivna, Prykhodko, Olha Oleksiivna, Sikora, Vitalii Zinoviiovych, Yarmolenkо, Olha Serhiivna, Бумейстер, Валентина Ивановна, Бумейстер, Валентина Іванівна, Демихова, Надежда Владимировна, Деміхова, Надія Володимирівна, Приходько, Ольга Алексеевна, Приходько, Ольга Олексіївна, Сикора, Виталий Зиновьевич, Сікора, Віталій Зіновійович, Ярмоленкo, Ольга Сергіївна, Ярмоленко, Ольга Сергеевна   +15 more
core   +1 more source

The new cardioprotector Monohydroxyethylrutoside protects against doxorubicin-induced inflammatory effects in vitro [PDF]

British Journal of Cancer, 2003
Besides its cardiotoxic effect, doxorubicin also elicits inflammatory effects in vivo. 7-Monohydroxyethylrutoside (monoHER) has recently been used as a protector against doxorubicin-induced cardiotoxicity in vivo. It is not known yet whether monoHER can also protect against doxorubicin-induced inflammatory effects.
Abou el Hassan, M.A., Verheul, H.M., Jorna, A.S., Schalkwijk, C.G., van Bezu, J., van der Vijgh, W.J.F., Bast, A.   +6 more
openaire   +5 more sources

Disribution kinetics of cardioprotector ALM-802 in rat organs and tissues

Pharmacokinetics and Pharmacodynamics, 2022
The distribution kinetics of a compound with cardioprotective activity, N1-(2,3,4-trimethoxybenzyl)-N2-{2-[(2,3,4-trimethoxybenzyl)amino] ethyl}-1,2-ethanediamine (ALM-802) in rat tissues and organs after single intragastric administration at a dose of 100 mg/kg. The values of ALM-802 tissue availability were determined.
O. Yu. Kravtsova, G. B. Kolyvanov, A. A. Litvin, P. O. Bochkov, V. P. Zherdev   +4 more
openaire   +2 more sources

Plant Sources, Extraction Methods, and Uses of Squalene

International Journal of Agronomy, Volume 2018, Issue 1, 2018., 2018
Squalene (SQ) is a natural compound, a precursor of various hormones in animals and sterols in plants. It is considered a molecule with pharmacological, cosmetic, and nutritional potential. Scientific research has shown that SQ reduces skin damage by UV radiation, LDL levels, and cholesterol in the blood, prevents the suffering of cardiovascular ...
M. Azalia Lozano-Grande, Shela Gorinstein, Eduardo Espitia-Rangel, Gloria Dávila-Ortiz, Alma Leticia Martínez-Ayala, José M. Alvarez-Suarez   +5 more
wiley   +1 more source