Results 41 to 50 of about 290 (164)

Growth hormone-releasing peptides and the heart: secretagogues or cardioprotectors? [PDF]

Cardiovascular Research, 2004
See article by Iwase et al. [13] in this issue. Growth hormone (GH) and insulin-like growth factor-1 (IGF-1) are multifunctional hormones with potent cardiotropic effects in prenatal and postnatal cardiac development. Evidence from animal and clinical studies has documented the beneficial effects of the GH-IGF-1 axis on cardiac hypertrophy and ...
openaire   +2 more sources

Cardioprotector effect of Phosphodiesterase 5 inhibitors in experimental model for Diabetes Mellitus

ABCS Health Sciences, 2021
Diabetes mellitus (DM) is considered a 21st century pandemic and is often associated with cardiovascular disease (CVD). The aim of this integrative review was to analyze the cardioprotective effects of phosdodiesterase-5 (PDE5i) inhibitors in experimental diabetes models. The articles were selected from the PubMed, SciElo and LILACS databases from 2014
Gilson Nogueira Freitas, Cristina de Oliveira Silva   +1 more
openaire   +2 more sources

Oxidative Stress, Apoptosis, and Mitochondrial Function in Diabetic Nephropathy

International Journal of Endocrinology, Volume 2018, Issue 1, 2018., 2018
Diabetic nephropathy (DN) is the second most frequent and prevalent complication of diabetes mellitus (DM). The increase in the production of oxidative stress (OS) is induced by the persistent hyperglycemic state capable of producing oxidative damage to the macromolecules (lipids, carbohydrates, proteins, and nucleic acids). OS favors the production of
Sonia Sifuentes-Franco, Diego Enrique Padilla-Tejeda, Sandra Carrillo-Ibarra, Alejandra Guillermina Miranda-Díaz, Ilias Migdalis   +4 more
wiley   +1 more source

Фармакологічна профілактика перенапруження серцево-судинної системи як фактор збереження здоров'я спортсменів [PDF]

, 2017
Due to the worsening of WADA's requirements regarding myocardial protection and the prohibition of the most commonly used trimetasidine and meldonium in sport, new directions for the use of cardioprotectors are needed.
Гуніна, Л.
core   +2 more sources

Place of tiotriazoline in the gallery of modern metabolitotropic medicines

Zaporožskij Medicinskij Žurnal, 2019
We want to show pharmacological characterization of Tiotriazoline, based on results of tentative analysis and clinical research, also features of its therapeutic action and advantage over another metabolitotropic cardio protectors.
I. F. Bielenichev, V. A. Vіzіr, V. Yo. Mamchur, O. V. Kuriata   +3 more
doaj   +1 more source

Дексмедетомидин как кардиопротектор в кардиохирургии (обзор) [PDF]

, 2017
The literature review presents an analysis of publications on the use of a selective α2-adrenergic receptor agonist (α2-AR) dexmedetomidine as a cardioprotector in cardiosurgical interventions.
I. A. Kozlov, I. O. Antonov, T. V. Klypa, И. А. Козлов, И. О. Антонов, Т. В. Клыпа   +5 more
core   +2 more sources

Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14‐3‐3η

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Gastrodin (GAS) is the major component isolated from the rhizome of the Chinese traditional medicinal herb “Tianma.” Many clinical studies have found that GAS protects cardiomyocytes in cardiovascular diseases, although the effects and underlying mechanisms on cardiovascular anoxia/reoxygenation (A/R) injury remain unknown.
Meifang Zhu, Wei Deng, Suhong Di, Mingming Qin, Dan Liu, Bo Yi, Jerzy Kruk   +6 more
wiley   +1 more source

Polyphenolic Compounds, Antioxidant, and Cardioprotective Effects of Pomace Extracts from Fetească Neagră Cultivar

Oxidative Medicine and Cellular Longevity, Volume 2018, Issue 1, 2018., 2018
Grape pomace is a potential source of natural antioxidant agents. Phenolic compounds and antioxidant and cardioprotective properties of fresh and fermented pomace extracts obtained from Vitis vinifera L. red variety Fetească neagră grown in Romania in 2015 were investigated. Grape pomace extracts total phenolic index, total tannins, total anthocyanins,
Ştefania Silvia Balea, Alina Elena Pârvu, Nastasia Pop, Fernando Zamora Marín, Marcel Pârvu, Ada Popolo   +5 more
wiley   +1 more source

Изучение острой и подострой токсичности субстанции с противогрибковым действием [PDF]

, 2017
В данной работе авторами исследована острая и подострая токсичность субстанции 2-(6-гидроксиметил-9-метил-2-(4-фторфенил)-5Н- пиридо[4',3':5,6]пирано[2,3-d]пиримидин-4-илсульфанил)-1-N- пиперидинилэтанона (производные 4Н-пиридо[4',3':5,6]пирано[2,3-d ...
Датхаев, У.М., Дербисбекова, У.Б., Момбеков, С.Е., Рахимов, К.Д., Шалабай, А.К., Шарапатдин, А.К.   +5 more
core  

Дослідження кардіопротекторної дії пастернаку посівного трави екстракту густого [PDF]

, 2020
Topicality. Modern drugs used to treat diseases of the cardiovascular system generally have a number of side effects. In this regard, the problem of developing and studying safe and effective drugs for the use in cardiology becomes relevant for ...
Galuzinska, L., Horiacha, L., Kyslychenko, V., Shpychak, O., Symonenko, N.   +4 more
core   +2 more sources