Molecular Medicine, 2023 Background The ischemia–reperfusion (IR) environment during deep hypothermic circulatory arrest (DHCA) cardiovascular surgery is a major cause of acute kidney injury (AKI), which lacks preventive measure and treatment. It was reported that cold inducible
Peiyao Zhang +9 more
doaj +1 more source
Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass [PDF]
, 1999 Objectives: The investigation centers on whether there is a reperfusion-induced specific cardiac inflammatory reaction after bypass surgery. Background: Cardiopulmonary bypass (CPB) leads to systemic inflammation.
Becker, Bernhard F. +5 more
core +1 more source
Is transfusion in coronary artery surgery a predictor or a cause of reduced long-term survival? [PDF]
, 2020 Background Transfusion is common after coronary bypass surgery. Transfused patients present with higher operative risk and an increased hazard ratio for curtailed long-term survival. There is debate as to whether transfusion itself may further exacerbate
Camilleri, Liberato, Manche, Alexander
core +1 more source
Evaluation of the Appropriate Root Pressure for Maintaining Heartbeat during an Aortic Cross-clamp for Primary Repair of the Aortic Arch in Premature Infants with Associated Cardiac Anomalies [PDF]
, 2010 We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ...
Honjo, Osami +5 more
core +1 more source
Aprotinin reduces cardiac troponin I release and inhibits apoptosis of polymorphonuclear cells during off-pump coronary artery bypass surgery [PDF]
, 2008 Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass-assisted cardiac surgery.
Bert, C. +9 more
core +2 more sources
Lipolysis generates platelet dysfunction after in vivo heparin administration [PDF]
, 2002 Heparin, when administered to patients undergoing operations using cardiopulmonary bypass, induces plasma changes that gradually impair platelet macroaggregation, but heparinization of whole blood in vitro does not have this effect.
Belcher, P.R. +5 more
core +1 more source
Albanian Journal of Trauma and Emergency Surgery, 2023 Introduction: In open heart surgery such as Coronary artery Bypass Grafting, valve repair or replacement, or some congenital heart disease, patients are connected to the Cardiopulmonary bypass machine [1].
Merita Zeka +4 more
doaj +1 more source
Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]
, 2011 Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Boehm, Olaf +9 more
core +2 more sources
Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]
, 2007 Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Buchan, Keith G. +9 more
core +1 more source
, 1999 Introduction Cardiopulmonary bypass (CPB) has been shown to induce a systemic inflammatory response similar to the local reaction seen after tissue damage [1].
D Johnson +6 more
core +1 more source