Results 31 to 40 of about 113,991 (266)

Acute cardiac inflammatory responses to postischemic reperfusion during cardiopulmonary bypass [PDF]

, 1999
Objectives: The investigation centers on whether there is a reperfusion-induced specific cardiac inflammatory reaction after bypass surgery. Background: Cardiopulmonary bypass (CPB) leads to systemic inflammation.
Becker, Bernhard F., Hartl, Heinz, Hähnel, Christoph, Massoudy, Parwis, Meisner, Hans, Zahler, Stefan   +5 more
core   +1 more source

CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathways

Molecular Medicine, 2023
Background The ischemia–reperfusion (IR) environment during deep hypothermic circulatory arrest (DHCA) cardiovascular surgery is a major cause of acute kidney injury (AKI), which lacks preventive measure and treatment. It was reported that cold inducible
Peiyao Zhang, Liting Bai, Yuanyuan Tong, Shengwen Guo, Wenlong Lu, Yue Yuan, Wenting Wang, Yu Jin, Peng Gao, Jinping Liu   +9 more
doaj   +1 more source

Successful Extracorporeal Life Support for Life-threatening Hypercapnia with Bronchiolitis Obliterans after Allogeneic Hematopoietic Stem Cell Transplantation [PDF]

, 2011
Bronchiolitis obliterans (BO) is a disease with a poor prognosis, and a key factor that limits long-term survival after allogeneic hematopoietic stem cell transplantation (HSCT).
Ichiba, Shingo, Kanehiro, Arihiko, Maeda, Yoshinobu, Miyahara, Nobuaki, Murakami, Toshi, Nagano, Osamu, Ochi, Nobuaki, Tanimoto, Mitsune, Tanimoto, Yasushi, Terado, Michihisa, Ujike, Yoshihito, Waseda, Koichi   +11 more
core   +1 more source

Evaluation of the Appropriate Root Pressure for Maintaining Heartbeat during an Aortic Cross-clamp for Primary Repair of the Aortic Arch in Premature Infants with Associated Cardiac Anomalies [PDF]

, 2010
We developed a new cardiopulmonary bypass (CPB) method to minimize myocardial damage during aortic arch reconstruction. In this method, coronary flow and heartbeat were stabilized by maintaining the aortic root pressure with an adjusted preload of the ...
Honjo, Osami, Ishino, Kozo, Kotani, Yasuhiro, Osaki, Satoru, Sano, Shunji, Suezawa, Takanori   +5 more
core   +1 more source

The effect of perioperative dexmedetomidine on postoperative delirium in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis of randomized controlled trials

BMC Anesthesiology
Background Dexmedetomidine is considered to have neuroprotective effects and may reduce postoperative delirium in both cardiac and major non-cardiac surgeries.
Xiaoli Zhuang, Lin Fu, Lan Luo, Ziyuan Dong, Yu Jiang, Ju Zhao, Xiaofang Yang, Feilong Hei   +7 more
doaj   +1 more source

Troponin I, and Lactic Acid variations, during Cardiopulmonary Bypass under Moderate Hypothermia vs Normothermia.

Albanian Journal of Trauma and Emergency Surgery, 2023
Introduction: In open heart surgery such as Coronary artery Bypass Grafting, valve repair or replacement, or some congenital heart disease, patients are connected to the Cardiopulmonary bypass machine [1].
Merita Zeka, Saimir Kuci, Blerim Arapi, Alfred Ibrahimi, Krenar Lilaj   +4 more
doaj   +1 more source

Aprotinin reduces cardiac troponin I release and inhibits apoptosis of polymorphonuclear cells during off-pump coronary artery bypass surgery [PDF]

, 2008
Objectives: In addition to blood-sparing effects, aprotinin may have cardioprotective and anti-inflammatory effects during cardiopulmonary bypass-assisted cardiac surgery.
Bert, C., Ceuppens, J., De Buck, F., Delforge, M., Kasran, A., Meyns, B., Sergeant, P., Van Duppen, V., Van Hemelrijck, J., Wouters, Patrick   +9 more
core   +2 more sources

Early Outcomes After Total Arch Replacement With Frozen Elephant Trunk in Elderly Patients With Acute Type A Aortic Dissection

AGING MEDICINE, EarlyView.
Across seven centers (2015–2023), we studied 1634 ATAAD patients undergoing TAR+FET and, after propensity matching (n = 699), compared elderly (≥ 60) versus non‐elderly (< 60) outcomes. Elderly patients had higher 30‐day mortality and complications (log‐rank p = 0.002), supporting individualized hybrid strategies, organ‐protective perioperative care ...
Jiajun Liang, Yuan Xue, Yeting Lou, Hao Han, Xiaohan Zhong, Zhou Liu, Tianxu Han, Meili Wang, Wenjian Jiang, Hongjia Zhang, Haiyang Li, Yuanfei Zhao   +11 more
wiley   +1 more source

Factors associated with prolonged length of stay following cardiac surgery in a major referral hospital in Oman: a retrospective observational study [PDF]

, 2016
Two objectives were set for this study. The first was to identify factors influencing prolonged postoperative length of stay (LOS) following cardiac surgery. The second was to devise a predictive model for prolonged LOS in the cardiac intensive care unit
Almashrafi, A, Alsabti, H, Aylin, P, Baskaran, B, Mukaddirov, M   +4 more
core   +1 more source

Small vesicles, big potential: A review of innovative exosome delivery and molecular mechanisms in preclinical myocardial infarction models

Animal Models and Experimental Medicine, EarlyView.
This narrative review discusses animal models of exosome‐based myocardial infarction treatments. Emerging techniques aim to improve exosome stability, targeting, and bioavailability for MI treatment as drug delivery vehicles and regenerative mediators that promote myocardial regeneration. Abstract Exosomes have emerged as promising therapeutic carriers,
Chayanisa Phutiyothin, Kovit Pattanapanyasat, Sarawut Kumphune   +2 more
wiley   +1 more source