Results 41 to 50 of about 544,745 (346)

Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery [PDF]

, 2020
Background Laboratory studies demonstrate glucose-insulin-potassium (GIK) as a potent cardioprotective intervention, but clinical trials have yielded mixed results, likely because of varying formulas and timing of GIK treatment and different clinical ...
Chen, Wensheng, Cui, Qin, Gao, Feng, Li, Jia, Liu, Jincheng, Ma, Xin-Liang, Wan, Yi, Yi, Dinghua, Yu, Shiqiang, Zhang, Yue, Zhao, Bijun, Zhao, Kun, Zhao, Rong   +12 more
core   +1 more source

Esketamine/Ketamine: Dual‐Action Mechanisms and Clinical Prospects beyond Anesthesia in Psychiatry, Immunology, and Oncology

Advanced Science, EarlyView.
Esketamine and ketamine are widely used for perioperative analgesia and anesthesia. Despite their established roles in analgesia, sedation, and anesthesia, as well as emerging antidepressant, anti‐tumor, and anti‐inflammatory effects, their clinical use is limited due to side effects and addiction potential.
Yinxin Wang, Jiangang Xu, Xinyu Zhou, Lu Che, Minghan Qiu, Yang Liu, Ming Gao, Zhen Yang   +7 more
wiley   +1 more source

Salvage resection of advanced mediastinal tumors [PDF]

, 2019
The surgical treatment of locally advanced mediastinal tumors invading the great vessels and other nearby structures still represent a tricky question, principally due to the technical complexity of the resective phase, the contingent need to carry out
Andreetti, Claudio, Ciccone, Anna Maria, D’Andrilli, Antonio, Ibrahim, Mohsen, Maurizi, Giulio, Menna, Cecilia, Poggi, Camilla, Rendina, Erino Angelo, Vanni, Camilla, Venuta, Federico   +9 more
core   +1 more source

Neuroprotective Strategies during Cardiac Surgery with Cardiopulmonary Bypass

International Journal of Molecular Sciences, 2016
Aortocoronary bypass or valve surgery usually require cardiac arrest using cardioplegic solutions. Although, in principle, in a number of cases beating heart surgery (so-called off-pump technique) is possible, aortic or valve surgery or correction of ...
A. Salameh, S. Dhein, I. Dähnert, N. Klein   +3 more
semanticscholar   +1 more source

Understanding the influence of transfusion and blood loss on tranexamic acid concentration in scoliosis surgery with blood loss

British Journal of Clinical Pharmacology, EarlyView.
Aims Tranexamic acid (TXA) stabilizes clot formation by inhibiting fibrin degradation and improves postoperative outcomes. However, rare adverse events (e.g., thrombosis, seizures) warrant dose–risk evaluation. This study examines how perioperative blood loss and transfusion practices affect TXA concentrations during paediatric scoliosis surgery ...
Paula Alexandra Sá, Luisa Barreiros, Marcela A. Segundo, Eugénia Cruz, Sibylle Langenecker   +4 more
wiley   +1 more source

Effect of mild hypothermia vs normothermia cardiopulmonary bypass on postoperative bleeding in patients undergoing coronary artery bypass grafting: protocol of a multi-center, randomized, controlled trial

BMC Surgery
Background Coronary artery bypass grafting (CABG) is often performed with hypothermic cardiopulmonary bypass (CPB) to reduce metabolic demands and protect the myocardium. However, hypothermia can increase bleeding risks and other complications.
Jing Wang, Tianlong Wang, Han Zhang, Qiaoni Zhang, Gang Liu, Shujie Yan, Qian Wang, Yuan Teng, Jian Wang, Qiang Hu, Bingyang Ji   +10 more
doaj   +1 more source

Impact of dexmedetomidine on mortality in critically ill patients with acute kidney injury: a retrospective propensity score matching analysis

BMJ Open, 2023
Objectives This study sought to estimate the effect of dexmedetomidine (DEX) administration on mortality in critically ill patients with acute kidney injury (AKI).Design A retrospective cohort study.Setting The study sourced its data from the ...
Peng Gao, Jinping Liu, He Wang, Wenting Wang, Yu Jin, Peiyao Zhang   +5 more
doaj   +1 more source

Genetic variation of TLR4 influences immunoendocrine stress response: an observational study in cardiac surgical patients [PDF]

, 2011
Introduction: Systemic inflammation (e.g. following surgery) involves Toll-like receptor (TLR) signaling and leads to an endocrine stress response. This study aims to investigate a possible influence of TLR2 and TLR4 single nucleotide polymorphisms (SNPs)
Boehm, Olaf, Bornstein, Stefan R., Grotemeyer, Dirk, Hamann, Lutz, Koch, Alexander, Kurt, Muhammed, Schott, Matthias, Schumann, Ralf R., Schwenke, Carsten, Zacharowski, Kai   +9 more
core   +2 more sources

Conversion to Cardiac Surgery During Elective and Urgent Transcatheter Aortic Valve Implantation: A Systematic Review and Meta‐Analysis

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Transcatheter aortic valve implantation (TAVI) has become an established treatment for severe aortic stenosis. However, the need for unplanned conversion to cardiac surgery (CS) during TAVI remains an infrequent but critical event. It is unclear whether this risk is higher in patients undergoing urgent procedures.
Nikolaos Ktenopoulos, Anastasios Apostolos, Dimitrios‐David Chlorogiannis, Ioannis Kachrimanidis, Panayotis Vlachakis, Marios Sagris, Theoni Theodoropoulou, Maria Drakopoulou, Andreas Synetos, George Latsios, Constantina Aggeli, Konstantinos Tsioufis, Konstantinos Toutouzas   +12 more
wiley   +1 more source

The organ-protective effects of nitric oxide in adult patients undergoing cardiac surgery with cardiopulmonary bypass: a systematic review and meta-analysis

BMC Anesthesiology
Background Postoperative organ dysfunction remains a major challenge in adult cardiac surgery with cardiopulmonary bypass (CPB), frequently involving the kidneys, heart, and lungs.
Jieru Zhang, Han Zhang, Jing Wang, Tianlong Wang, Luyu Bian, Zhenzhen Li, Jian Wang, Yuan Teng, Gang Liu, Shujie Yan, Bingyang Ji   +10 more
doaj   +1 more source