Journal of the American College of Cardiology, 2008 The term cardiorenal syndrome (CRS) increasingly has been used without a consistent or well-accepted definition. To include the vast array of interrelated derangements, and to stress the bidirectional nature of heart-kidney interactions, we present a new classification of the CRS with 5 subtypes that reflect the pathophysiology, the time-frame, and the
Ronco C +4 more
openaire +3 more sources
Apoptosis signal-regulating kinase 1 inhibition attenuates cardiac hypertrophy and cardiorenal fibrosis induced by uremic toxins: Implications for cardiorenal syndrome. [PDF]
PLoS ONE, 2017 Intracellular accumulation of protein-bound uremic toxins in the setting of cardiorenal syndrome leads to adverse effects on cardiorenal cellular functions, where cardiac hypertrophy and cardiorenal fibrosis are the hallmarks. In this study, we sought to
Feby Savira +12 more
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Diabetic kidney disease. new clinical and therapeutic issues. Joint position statement of the Italian Diabetes Society and the Italian Society of Nephrology on "the natural history of diabetic kidney disease and treatment of hyperglycemia in patients with type 2 diabetes and impaired renal function" [PDF]
, 2019 Recent epidemiological studies have disclosed heterogeneity in diabetic kidney disease (DKD). In addition to the classical albuminuric phenotype, two new phenotypes have emerged, i.e., “nonalbuminuric renal impairment” and “progressive renal decline ...
Barutta, Federica +7 more
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Platelets of patients with chronic kidney disease demonstrate deficient platelet reactivity in vitro [PDF]
, 2012 Background In patients with chronic kidney disease studies focusing on platelet function and properties often are non-conclusive whereas only few studies use functional platelet tests.
A Aggarwal +31 more
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Cardiorenal disease connection during post-menopause: The protective role of estrogen in uremic toxins induced microvascular dysfunction [PDF]
, 2017 Female gender, post-menopause, chronic kidney disease (CKD) and (CKD linked) microvascular disease are important risk factors for developing heart failure with preserved ejection fraction (HFpEF).
Asselbergs, F.W. (Folkert) +7 more
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BMC Cardiovascular Disorders, 2018 Background Severe aortic stenosis (AS) may lead to acute decompensated heart failure resistant to medical treatment. Here, we report a successful emergent transcatheter aortic valve replacement (TAVR) in a patient presenting with decompensated severe AS ...
Hongju Kim, Jung-Hee Lee
doaj +1 more source
The carotid body as a therapeutic target for the treatment of sympathetically mediated diseases [PDF]
, 2013 [no ...
Abdala, Ana P +13 more
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Renal function, electrolytes, and congestion monitoring in heart failure. [PDF]
, 2019 Congestion, renal function, and electrolyte imbalance (particularly potassium) are common problems in the management of the complex multi-morbid patient with heart failure (HF).
Chioncel, O +4 more
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Cardiorenal syndrome and diabetes: an evil pairing
Frontiers in Cardiovascular Medicine, 2023 Cardiorenal syndrome (CRS) is a pathology where the heart and kidney are involved, and the deterioration of one of them leads to the malfunction of the other. Diabetes mellitus (DM) carries a higher risk of HF and a worse prognosis.
Ana Belén Méndez Fernández +5 more
doaj +1 more source
Histopathological Changes in the Kidney following Congestive Heart Failure by Volume Overload in Rats [PDF]
, 2017 Background. This study investigated histopathological changes and apoptotic factors that may be involved in the renal damage caused by congestive heart failure in a rat model of infrarenal aortocaval fistula (ACF). Methods.
Aboryag, Noureddin B. +7 more
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