Results 41 to 50 of about 1,137,782 (176)

New Insight in Cardiorenal Syndrome: From Biomarkers to Therapy [PDF]

, 2023
Cardiorenal syndrome consists in the coexistence of acute or chronic dysfunction of heart and kidneys resulting in a cascade of feedback mechanisms and causing damage to both organs associated with high morbidity and mortality.
Giovanna Gallo, Oreste Lanza, Carmine Savoia   +2 more
core   +1 more source

Chronic cardiorenal syndrome: cardio-renal protective effect of SGLT2i

Renal Failure
Objectives Chronic cardiorenal syndrome (types 2 and 4) arises from chronic dysfunction of either the heart or kidneys, leading to progressive deterioration of the other organ.
Yixin Zhu, Chenxi Lv, Hanqi Yang, Qian Lu, XuChen Wang, Yueqi Zhang, Maojuan Guo, Bo Yang   +7 more
doaj   +1 more source

A novel case of acute glomerulonephritis with concurrent acute non-rheumatic myocarditis following group a streptococcal infection

Journal of International Medical Research, 2023
Streptococcal infection is a common cause of acute glomerulonephritis. Cardiac damage associated with streptococcal infection commonly occurs in acute rheumatic fever.
Shihui Hou, Jie Yang, Fei Xiao, Huanzi Dai   +3 more
doaj   +1 more source

Plasma homocysteine and cardiovascular risk in heart failure with and without cardiorenal syndrome [PDF]

, 2010
Plasma homocysteine (Hcy) has been associated with an increased cardiovascular (CV) risk in patients with chronic heart failure (CHF). Thus, we investigated whether Hcy has a prognostic impact on CV events in CHF-patients with and without cardiorenal ...
Burri, Sonja, Hess, Otto M., Hullin, Roger, Martinelli, Michele, Mohacsi, Paul, Maurer, Michaela, de Marchi, Stefano   +6 more
core   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Serum biochemical profile in case of cardiorenal syndrome in cats with hypertrophic cardiomyopathy

Ветеринария сегодня
Veterinary specialists have lately observed comorbidity of heart and kidney diseases known as cardiorenal syndrome. Cardiorenal syndrome is typically defined as dysfunction of a primarily intact kidney under the influence of a complex of pathogenetic ...
Yu. A. Vatnikov, E. D. Sotnikova, V. I. Kuznetsov, A. A. Razumova, I. V. Shchurov, O. A. Petrukhina, A. A. Rudenko   +6 more
doaj   +1 more source

CX3CL1 Worsens Cardiorenal Dysfunction and Serves as a Therapeutic Target of Canagliflozin for Cardiorenal Syndrome

Frontiers in Pharmacology, 2022
The prognosis of cardiorenal dysfunction induced by diabetes mellitus (DM), which belongs to cardiorenal syndrome type 5, is poor and its pathogenesis remains elusive. We have reported that CX3CL1 exacerbated heart failure and direct inhibition of CX3CL1
Cankun Zheng, Wanling Xuan, Zhenhuan Chen, Zhenhuan Chen, Rui Zhang, Xiaoxia Huang, Yingqi Zhu, Siyuan Ma, Kaitong Chen, Lu Chen, Mingyuan He, Hairuo Lin, Wangjun Liao, Jianping Bin, Jianping Bin, Yulin Liao, Yulin Liao   +16 more
doaj   +1 more source

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Renal protective effects and mechanisms of the angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome

, 2021
Aims This study investigated the renal protective effects and mechanisms of angiotensin receptor-neprilysin inhibitor LCZ696 in mice with cardiorenal syndrome.
Ying Li, Rong Li, Shuai Shao, Ya Suo, Qiankun Bao, Meng Yua, Gary Tse, Kai Rong, Tong Liu, Yue Zhang, Guangping Li, Li Kang   +11 more
core   +1 more source

Role of selenium in the pathophysiology of cardiorenal anaemia syndrome

ESC Heart Failure, Volume 12, Issue 2, Page 770-780, April 2025.
Abstract Chronic kidney disease (CKD) and cardiovascular disease (CVD) have multiple bidirectional mechanisms, and anaemia is one of the critical factors that are associated with the progression of the two disorders [referred to as cardiorenal anaemia syndrome (CRAS)].
Shigeyuki Arai, Minoru Yasukawa, Shigeru Shibata   +2 more
wiley   +1 more source