Results 61 to 70 of about 1,137,782 (176)

Clinical and instrumental features of cardiorenal syndrome in cats with hypertrophic cardiomyopathy

RUDN Journal of Agronomy and Animal Industries
This research presents novel insights into the temporal dynamics of clinical and instrumental parameters pertaining to the emergence of cardiorenal syndrome in feline patients afflicted with hypertrophic cardiomyopathy.
Varvara M. Byakhova, Olesya A. Petrukhina, Elena A. Notina, Irina A. Bykova   +3 more
doaj   +1 more source

CARDIORENAL SYNDROME IN CHRONIC HEART FAILURE: PATHOGENESIS, DIAGNOSTICS, PROGNOSIS AND OPPORTUNITIES FOR TREATMENT

Российский кардиологический журнал, 2017
The review focuses on cardiorenal syndrome developing in patients with chronic heart failure. The specifics of pathogenesis is discussed, as diagnostics and prognosis, with emphasis on the opportunities of modern biomarker strategy.
E. A. Medvedeva, N. V. Shilyaeva, E. N. Iskhakov, Yu. V. Schukin   +3 more
doaj   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Early Dapagliflozin and Melatonin Treatment Ameliorated LV Fibrosis via Suppressing TGF‐β1/Smads and Activating Nrf2‐ARE Signaling in MI Rodent

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study tested whether combined dapagliflozin (DAPA) and melatonin (Mel) therapy was superior to merely one for ameliorating the left ventricular (LV) fibrosis/remodeling and improving LV ejection fraction (LVEF) in rats after acute myocardial infarction (AMI). In vitro study demonstrated that DAPA treatment significantly suppressed the TGF‐
Jiunn‐Jye Sheu, Jui‐Ning Yeh, Han‐Tan Chai, John Y. Chiang, Chi‐Ruei Huang, Jun Guo, Hon‐Kan Yip   +6 more
wiley   +1 more source

In reply: Cardiorenal syndrome

Cleveland Clinic Journal of Medicine, 2018
We thank Dr. Freda for his remarks and observations. Certainly, the clinical importance of this entity and the challenge it poses to clinicians cannot be overemphasized. We concur with the overall message and reply to his specific comments: We completely agree that clinical data-gathering is ...
Guramrinder S, Thind, Mark, Loehrke, Jeffrey L, Wild   +2 more
openaire   +2 more sources

cardiorenal syndrome [PDF]

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroduction. Cardiorenal syndrome (CRS) is a condition characterized by the complex bidirectional relationship between the heart and kidneys, leading to ...
Purteanu, Lilia, Grib, Livi
core   +1 more source

From cytokine storm to renal scarring in diabetic kidney disease: Biomarkers, risk stratification, and precision therapeutics

Precision Medical Sciences, EarlyView.
Hyperglycemia‐driven cytokine activation initiates a sustained inflammatory cascade in diabetic kidney disease, promoting cellular injury and fibrogenic signaling. Integrating cytokine‐based biomarkers with risk stratification enables precision therapeutics that target inflammation and fibrosis, ultimately aiming to halt progression from early renal ...
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Halting the Progression of Acute Kidney Injury: A Tubular‐Inspired Reusable Detoxifier Against Protein‐Bound Uremic Toxins and Oxidative Stress

SusMat, EarlyView.
This graphical ToC illustrates a tubular‐inspired detoxifier (SDCMs–DS) that halts acute kidney injury progression. Inspired by proximal tubular epithelial cells (PTECs), the biomimetic design combines dissociation‐adsorption clearance of protein‐bound uremic toxins (PBUTs) with antioxidant protection. During hemoperfusion, danshensu (DS) released from
Yilin Wang, Jiahao Liang, Xijing Yang, Xin Song, Yujie Xiao, Xiran Zhou, Hongyu Xiang, Shujing Wang, Shengjun Cheng, Xianda Liu, Yu Chen, Weifeng Zhao, Changsheng Zhao   +12 more
wiley   +1 more source

Therapeutic Management of Cardiorenal Syndrome in A Non-Descript Dog

<p><span>Cardiorenal syndrome is a multi-organ disorder of heart and kidneys whereby acute or chronic dysfunction in one organ may induce acute or chronic dysfunction of the other. Cardiorenal syndrome occur mostly due to decreased glomerular
Therapeutic Management of Cardiorenal Syndrome in A Non-Descript Dog
core   +1 more source

Gut microbiota dysbiosis in the inflammatory pathogenesis of diabetic retinopathy

VIEW, EarlyView.
This graphical abstract illustrates how gut dysbiosis drives diabetic retinopathy through the gut‐retina axis, a process unfolding in three interconnected stages. First, in the gut, a decrease in beneficial bacteria and an increase in pro‐inflammatory taxa compromise the intestinal barrier, causing a “leaky gut” that allows LPS to translocate into the ...
Junyan Hu, Jingxiang Zhong
wiley   +1 more source