Results 51 to 60 of about 32,244 (241)

The Diagnosis That Arrived Decades Late: Living Without and Then With Myhre Syndrome

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (MIM #139210) is a rare multisystem disorder first described in 1981, characterized by short stature, neurodevelopmental delay, joint contractures, and cardiopulmonary complications. Its molecular basis, recurrent pathogenic variants in SMAD4, was not discovered until 2011. This narrative is based on a review of medical records,
Abdallah F. Elias
wiley   +1 more source

Comparing the outcomes of the technology‐enhanced learning of sectional anatomy with and without preceding demonstrations: A study about the worked‐example effect in anatomy education

Anatomical Sciences Education, EarlyView.
Abstract The examination of anatomical cross‐sections can facilitate the understanding of spatial and clinical anatomy. Visualization technologies, with dynamic and interactive displays, can be used to learn sectional anatomy in a mostly self‐directed manner.
Guilherme Reis Borges Coelho Fonseca, George Lim Tipoe, Fraide Augustin Ganotice Jr   +2 more
wiley   +1 more source

TRACKING OF CARDIORESPIRATORY FITNESS FROM CHILDHOOD TO EARLY ADOLESCENCE: MODERATION EFFECT OF SOMATIC MATURATION

Revista Paulista de Pediatria, 2019
Objective: To evaluate cardiorespiratory fitness’ tracking from childhood to adolescence, as well as to test the moderation role of somatic maturation.
André Oliveira Werneck, Danilo Rodrigues Silva, Ricardo Ribeiro Agostinete, Rômulo Araújo Fernandes, João Valente-dos-Santos, Manuel João Coelho-e-Silva, Enio Ricardo Vaz Ronque   +6 more
doaj   +1 more source

Possible therapeutic repositioning of valproic acid: From epileptic seizures to acute kidney injury

British Journal of Clinical Pharmacology, EarlyView.
Valproic acid, an anticonvulsant, may be repositioned to prevent acute kidney injury due to ischemia followed by reperfusion. It preserves renal functions, electrolyte homeostasis and active sodium transport in kidney tubules, and blocks the onset of hypertension.
Danilo Alves‐Bezerra, Luiza B. Negreiros, Amaury Pereira‐Acácio, Isadora G. Almeida, João P. M. Veloso‐Santos, Jarlene A. Lopes, Glória Costa‐Sarmento, Humberto Muzi‐Filho, Adalberto Vieyra   +8 more
wiley   +1 more source

Supratherapeutic drug concentration triggers: A novel data‐driven approach to assess their value for medication safety surveillance in intensive care

British Journal of Clinical Pharmacology, EarlyView.
Aims Electronic triggers (e‐triggers) are used as screening signals to detect potential adverse drug events (ADEs) and offer an effective system level approach for medication safety surveillance. Their clinical utility is typically evaluated through time‐consuming manual chart review by experts, limiting implementation.
Anne Paulien Langermans, Izak A. R. Yasrebi‐de Kom, Dylan Wayne de Lange, Nicolette Fransisca de Keizer, Joanna E. Klopotowska, on behalf of the RESCUE Study group, C. S. C. Bouman, E. N. van Roon, P. F. Schutte, J. ten Cate, D. van Balen, S. Hendriks, C. Lau, W. J. Vermeijden, A. Beishuizen, J. B. Masselink, P. E. Spronk, H. J. M. van Kan, P. W. de Feiter, E. J. Wils, A. Wieringa, A. J. Valkenburg, W. M. van den Bergh, M. H. Renes, W. Bult, E. de Jonge, M. Hoeksema, E. J. Wesselink, I. M. Purmer, B. E. Bosma, S. H. W. van Bree, H. J. W. Lammers, R. J. Bosman, E. J. F. Franssen, A. Karakus, M. Sigtermans, E. M. Kuck, D. A. Dongelmans, M. J. H. Aries, E. V. Uijtendaal, M. C. Reuland   +40 more
wiley   +1 more source

Hemopexin Purification From Human Cohn Fraction IV Paste and Its Biophysical Characterization and Functional Evaluation in Sickle Cell Disease Mice

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Hemopexin (Hpx) is an acute phase plasma protein that is responsible for sequestration and removal of cell‐free heme with very high affinity (Kd < 1 pM). Hpx expression in liver cells is induced following an inflammatory event such as severe hemolysis. Therefore, plasma Hpx has potential clinical relevance due to its' ability to bind free heme,
Shuwei Lu, Saini Setua, Mohd A. Khan, Aaradhya Bansal, Quintin O'Boyle, Pedro Cabrales, David C. Irwin, Paul W. Buehler, Andre F. Palmer   +8 more
wiley   +1 more source

Feeling Better Before, Not After: An Ecological Momentary Assessment of Affect Around Exercise in Women With Eating Disorders

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Maladaptive exercise includes excessive, compulsive, or compensatory exercise and is a common eating‐disorder (ED) symptom associated with increased severity, slower rates‐of‐recovery, and faster rates‐of‐relapse. Affect‐regulation theories posit that maladaptive exercise functions to reduce high negative affect (NA), although ...
Danielle A. N. Chapa, Kelsie T. Forbush, Yiyang Chen, Courtney E. Costain, Samiya I. Rasheed   +4 more
wiley   +1 more source

Epidemiology of Intensive Nutritional Interventions and Restraints in Hospitalizations for Anorexia Nervosa: Annual National Trends of the United States

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Despite the clinical relevance of enteral and parenteral tube feeding and restraint use in anorexia nervosa (AN), national‐level data on their use have remained limited, particularly for total parenteral nutrition (TPN) and percutaneous endoscopic gastrostomy (PEG).
Hiroyasu Ino, Nancy S. Jecker, Yoshiyuki Takimoto, Eisuke Nakazawa   +3 more
wiley   +1 more source

The Metabolic Signature of Cardiorespiratory Fitness

Scandinavian Journal of Medicine & Science in Sports
ABSTRACT High cardiorespiratory fitness (CRF) is associated with better overall health. This study aimed to find a metabolic signature associated with CRF to identify health‐promoting effects. CRF based on cardiopulmonary exercise testing, targeted and untargeted metabolomics approaches based on mass spectrometry, and clinical data ...
Julia Bork, Marcello R. P. Markus, Ralf Ewert, Matthias Nauck, Christian Templin, Henry Völzke, Gabi Kastenmüller, Anna Artati, Jerzy Adamski, Marcus Dörr, Nele Friedrich, Martin Bahls   +11 more
openaire   +2 more sources

Cardiorespiratory fitness in breast cancer survivors [PDF]

SpringerPlus, 2013
Maximal oxygen uptake (VO2max) has been used to assess risk for all-cause mortality and cardiovascular disease (CVD), and low VO2max has recently been associated with increased mortality from breast cancer. The purpose of this study was to determine the proportion of breast cancer survivors with 2 or more risk factors for CVD exhibiting a low VO2max ...
Burnett, David, Kluding, Patricia, Porter, Charles, Fabian, Carol, Klemp, Jennifer   +4 more
openaire   +2 more sources