Evaluation of Anti-Inflammatory Activity of the New Cardiotonic Steroid γ-Benzylidene Digoxin 8 (BD-8) in Mice. [PDF]
Ferreira DA +11 more
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Individual and Combined Cardioprotective Effects of 1,25(OH)<sub>2</sub>D<sub>3</sub> and Dimethyl Fumarate in an Isoproterenol-Induced Myocardial Injury Model. [PDF]
Karpuzoğlu FH +9 more
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Cardiovascular Protection with Sulfasalazine During Doxorubicin Challenge: Evidence from Oxidative and Histologic Endpoints. [PDF]
Ozhan O +8 more
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Development of CPA-Catalyzed β-Selective Reductive Amination of Cardenolides for the Synthesis and Biological Evaluation of Hydrolytically Stable Analogs. [PDF]
Perry N +3 more
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Effect of pimobendan on myocardial injury and systolic dysfunction in a canine model of supraventricular tachyarrhythmia. [PDF]
Hirao D +8 more
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Levosimendan in Cardiac Arrest (LeiCA): Protocol for a Randomized, Double-Blind, Phase II Clinical Trial. [PDF]
Rysz S +6 more
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Mechanistic Insights into the Antihypertensive and Cardioprotective Actions of Corosolic Acid: A Narrative Review. [PDF]
Chen F, Tew WY, Ong MT, Yam MF.
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Procedural Characteristics and Safety of Slender Percutaneous Coronary Intervention: Slender Is Better. [PDF]
Yoshimachi F +11 more
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The therapeutic potential of novel cardiotonic agents
Expert Opinion on Investigational Drugs, 2003During the course of treatment of heart failure patients, cardiotonic agents are inevitable for improvement of myocardial dysfunction. Clinically available agents, such as beta-adrenoceptor agonists and selective phosphodiesterase 3 inhibitors, act mainly via cyclic AMP/protein kinase A-mediated facilitation of Ca(2+) mobilisation (upstream mechanism).
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