Results 201 to 210 of about 3,273,209 (295)

GLP-1 receptor agonists synergistic effects of metabolic reprogramming and cardioprotection. [PDF]

open access: yesFront Endocrinol (Lausanne)
Wang X   +9 more
europepmc   +1 more source
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The therapeutic potential of novel cardiotonic agents

Expert Opinion on Investigational Drugs, 2003
During the course of treatment of heart failure patients, cardiotonic agents are inevitable for improvement of myocardial dysfunction. Clinically available agents, such as beta-adrenoceptor agonists and selective phosphodiesterase 3 inhibitors, act mainly via cyclic AMP/protein kinase A-mediated facilitation of Ca(2+) mobilisation (upstream mechanism).
M. Endoh
openaire   +3 more sources

Quantitative structure - activity relationships of cardiotonic agents

Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques, 2000
Quantitative structure-activity relationships (QSARs) of different cardiotonic agents are presented. A critical analysis of all QSARs provides a very vivid picture of the mechanisms of varying cardiotonic agents. The cardiotonics can be broadly put into 2 categories: cardiac glycosides and nonglycoside cardiotonics, which include phosphodiesterase of ...
S. Gupta
openaire   +3 more sources

Cardiotonic agents in the management of chronic cardiac failure

American Heart Journal, 1982
Heart failure is a syndrome with distinct clinical signs and symptoms. The severity of cardiac failure and a deterioration in functional capacity can be determined by a progressive exercise test and by the noninvasive determination of maximum oxygen uptake.
K T, Weber, V, Andrews, J S, Janicki
openaire   +3 more sources

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