Results 111 to 120 of about 86,211 (132)

Novel stereoselective bufadienolides reveal new insights into the requirements for Na(+), K(+)-ATPase inhibition by cardiotonic steroids. [PDF]

Sci Rep, 2016
Tang HJ, Ruan LJ, Tian HY, Liang GP, Ye WC, Hughes E, Esmann M, Fedosova NU, Chung TY, Tzen JT, Jiang RW, Middleton DA.   +11 more
europepmc   +1 more source

Time- and dose dependent actions of cardiotonic steroids on transcriptome and intracellular content of Na⁺ and K⁺: a comparative analysis. [PDF]

Sci Rep, 2017
Klimanova EA, Tverskoi AM, Koltsova SV, Sidorenko SV, Lopina OD, Tremblay J, Hamet P, Kapilevich LV, Orlov SN.   +8 more
europepmc   +1 more source

Na⁺_i,K⁺_i-Dependent and -Independent Signaling Triggered by Cardiotonic Steroids: Facts and Artifacts. [PDF]

Molecules, 2017
Orlov SN, Klimanova EA, Tverskoi AM, Vladychenskaya EA, Smolyaninova LV, Lopina OD.   +5 more
europepmc   +1 more source

A New Animal Model to Study Endogenous Cardiotonic Steroids and the Progression of Cardiovascular Events in Salt-Sensitive Hypertension. [PDF]

Int Arch Transl Med, 2015
Estape ES, Torres-Negron I, Gonzalez L, Martinez-Maldonado M.   +3 more
europepmc   +1 more source

From Chemical Defense to Drug Discovery: Bioactive Molecules, Pharmacological Activities, and Therapeutic Potential of <i>Rhaebo guttatus</i> and <i>Rhinella marina</i> Secretions. [PDF]

Biology (Basel)
Da Silva BED, Albiero LR, Sinhorin VDG.
europepmc   +1 more source

Digoxin Derivative BD-8 Attenuates Oxidative Stress and Neuroinflammation in an LPS-Induced Experimental Model. [PDF]

Cell Biochem Biophys
Souza VKB, Ferreira DA, Arantes APR, de Sá Figueiredo E, Fonseca MFR, de Oliveira Ferreira PY, Ribeiro MR, Ghedini PC, de Freitas Ribeiro AA, Perez Villar JAF, de Castro Lima M, Garcia IJP, Santos HL, Scavone C, Mascarenhas SR, Leite JA.   +15 more
europepmc   +1 more source

Cardiac Glycoside 3β-Bufalin Suppresses Cancer Cell Proliferation by Coupling with Na⁺,K⁺-ATPase and Volume-Regulated Anion Channel Within Membrane Microdomains. [PDF]

Int J Mol Sci
Fujii T, Shimizu T, Shimizu Y, Katoh M, Okumura T, Fujii T, Sakai H.   +6 more
europepmc   +1 more source

Biocatalytic C14-Hydroxylation on Androstenedione Enabled Modular Synthesis of Cardiotonic Steroids

ACS Catalysis, 2022
Cardiotonic steroids are a unique class of natural products, possessing a steroid framework with a characteristic hydroxyl group at C14 and a β-oriented five- or six-membered unsaturated lactone substituent at C17. Installation of a hydroxyl group at the
Ai Hua Zhang, Hui Ming Ge, Zhi Kai Guo
exaly   +2 more sources

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Na+,K+-ATPase and Cardiotonic Steroids in Models of Dopaminergic System Pathologies

Biomedicines, 2023
Denis A Abaimov, Rogneda Kazanskaya, Alexander Lopachev   +2 more
exaly  

Binding of cardiotonic steroids to Na+,K+-ATPase in the E2P state

Proceedings of the National Academy of Sciences of the United States of America, 2021
Haruo Ogawa, Chikashi Toyoshima, Bente Vilsen   +2 more
exaly