Results 181 to 190 of about 97,116 (340)

Incidence and Predictors of Doxorubicin-Induced Cardiotoxicity in Breast Cancer Patients at a Tertiary Academic Hospital in Indonesia: A Retrospective Cohort Study. [PDF]

Hosp Pharm
Fitrianti AE, Astuti A, Reyaan IBM, Hendrayana T, Rahmah SA, Anggadiredja K, Zazuli Z.   +6 more
europepmc   +1 more source

Mechanisms of Cardiotoxicity Associated with Tyrosine Kinase Inhibitors in H9c2 Cells and Mice

, 2020
Jamal Bouitbir, Abdallah Alshaikhali, Miljenko V. Panajatovic, Vanessa Fabienne Abegg, Franziska Paech, Stephan Krähenbühl, V Abegg, Basle, Switzerland, F Paech, Basle, Switzerland, S Krähenbühl, Basle, Switzerland   +11 more
openalex   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu, Xingju Zou, Yang Zheng, Chen Sun, Cheng Peng   +4 more
wiley   +1 more source

Cardiotoxicity of Chemoradiotherapy in Patients With Esophageal Cancer: A Systematic Review. [PDF]

Cureus
Kocherry C, Shamim H, Jhakri K, Al-Shudifat M, Sumra B, Yu AK.   +5 more
europepmc   +1 more source

IL-1β blockade prevents cardiotoxicity and improves the efficacy of immune checkpoint blockers and chemotherapy against pancreatic cancer in mice with obesity

Nilesh P. Talele, Heena Kumra, Igor L. Gomes‐Santos, William W. Ho, Patrik L. Andersson, Marie Siwicki, Peigen Huang, Dan G. Duda, Mikäel J. Pittet, Dai Fukumura, Rakesh K. Jain   +10 more
openalex   +1 more source

Bruton tyrosine kinase (Btk) in neutrophils is indispensable for initiating and maintaining skin inflammation in a model of pemphigoid diseases

British Journal of Pharmacology, EarlyView.
Background and Purpose Bruton tyrosine kinase (Btk) is essential for B cell function. Its role in myeloid cells is less understood. Greater insights into Btk significance in myeloid cells are needed to evaluate its potential as a therapeutic target during the effector phase of antibody‐induced autoimmune diseases, where inhibiting autoantibody ...
Henning Olbrich, Paul Schilf, Sripriya Murthy, Sina Gonther, Mareike Neumann, Christoph M. Hammers, Jasper N. Pruessmann, Christian D. Sadik   +7 more
wiley   +1 more source

Enhancing Breast Cancer Survivorship Care: The Role of Nurses in Post‐Treatment Follow‐Up—A Scoping Review

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To examine the role of nurses in providing post‐treatment follow‐up care to breast cancer survivors, and to assess the impact of this care on survivors' satisfaction. Methods Scoping review. Data Sources An electronic literature search from PubMed and CINAHL databases was conducted, covering the period from 2013 to November 2023.
Judith Gálvez‐Sánchez, Nelia Soto‐Ruiz, Paula Escalada‐Hernández, Ana Carolina Andrade Biaggi Leite, Cristina García‐Vivar   +4 more
wiley   +1 more source

Transcriptomic Insights into Early Diagnosis of Doxorubicin-Induced Cardiotoxicity in a Rat Model [PDF]

Emilia Anca, I Pavel, Emilia Licărete, C Roşioru, Camelia Dobre, Manuela Banciu   +5 more
openalex   +1 more source

Dual therapy with allicin and metformin provides superior cardioprotection against doxorubicin-induced cardiotoxicity in rats compared to monotherapy. [PDF]

Front Pharmacol
Mojamel M, Al-Mahbashi H, Al-Nabehi A.
europepmc   +1 more source