MicroRNA Signatures and Machine Learning Models for Predicting Cardiotoxicity in HER2-Positive Breast Cancer Patients. [PDF]
Anastasiou M +14 more
europepmc +1 more source
Abstract BACKGROUND Narrow‐leaved lupins (NLL, Lupinus angustifolius L.) is recognized as a climate‐resilient protein crop but its use in food and feed is frequently limited by toxic quinolizidine alkaloids (QAs). The effect of intercropping with spring oat (Avena sativa L.) on grain QA content has not yet been quantified.
Yannik Schlup +5 more
wiley +1 more source
Machine Learning for Predicting Human Drug-Induced Cardiotoxicity: A Scoping Review. [PDF]
Han JY +5 more
europepmc +1 more source
Cardiac digital twins: Modelling the arrhythmic substrate of chemotherapy
The Journal of Physiology, EarlyView.
Radomir Chabiniok, Vlad G. Zaha
wiley +1 more source
Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li +6 more
wiley +1 more source
The emerging role of echocardiography-based techniques in cardio-onco-hematology. [PDF]
Zhang Y, Xie M, Wang J, Zhang B.
europepmc +1 more source
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura +5 more
wiley +1 more source
[Expression of Concern] Glibenclamide exacerbates adriamycin-induced cardiotoxicity by activating oxidative stress-induced endoplasmic reticulum stress in rats. [PDF]
Liu ML, Wang ML, Lv JJ, Wei J, Wan J.
europepmc +1 more source
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source
Gut microbiome and chemotherapy-induced cardiotoxicity: A systematic review of evidence and emerging therapies. [PDF]
Abdulaal R +10 more
europepmc +1 more source

