Results 211 to 220 of about 43,976 (245)
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Expert Opinion on Drug Safety, 2006
The use of anthracyclines is limited by dose-dependent cardiotoxicity. Three forms of anthracycline cardiotoxicity are described; an immediate pericarditis-myocarditis syndrome, an early onset chronic progressive CHF developing during or shortly after therapy and late-onset cardiotoxicity presenting years following treatment.
Robin L, Jones +2 more
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The use of anthracyclines is limited by dose-dependent cardiotoxicity. Three forms of anthracycline cardiotoxicity are described; an immediate pericarditis-myocarditis syndrome, an early onset chronic progressive CHF developing during or shortly after therapy and late-onset cardiotoxicity presenting years following treatment.
Robin L, Jones +2 more
openaire +2 more sources
2007
The clinical use of doxorubicin and other quinone-hydroquinone anticancer anthracyclines is limitedby a dose-related cardiotoxicity. Here, we review the correlation of cardiotoxicity of doxorubicinwith its peak plasma concentration and diffusion in the heart, followed by reductive bioactivation or oxidativeinactivation.
Pierantonio, Menna +3 more
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The clinical use of doxorubicin and other quinone-hydroquinone anticancer anthracyclines is limitedby a dose-related cardiotoxicity. Here, we review the correlation of cardiotoxicity of doxorubicinwith its peak plasma concentration and diffusion in the heart, followed by reductive bioactivation or oxidativeinactivation.
Pierantonio, Menna +3 more
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Cyclophosphamide cardiotoxicity
European Journal of Pediatrics, 1980A 12-year-old boy with aplastic anemia developed severe but reversible cardiac failure after treatment with 200 mg/kg cyclophosphamide (4 x 50 mg/kg on four consecutive days) given as preparation for bone marrow grafting. This and previously reported cases demonstrate the possibility of cardiotoxicity after high doses of the drug.
G, von Bernuth +6 more
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Emergency Medicine Clinics of North America, 1995
This article describes the cardiovascular effects and treatment of patients who have used cardiotoxic drugs. The discussion includes cocaine, methamphetamine, cyclic antidepressants, calcium channel blockers, beta-blockers, and digoxin. The authors review treatment controversies and emphasize the acute aspects of toxicity commonly seen in the emergency
R W, Derlet, B Z, Horowitz
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This article describes the cardiovascular effects and treatment of patients who have used cardiotoxic drugs. The discussion includes cocaine, methamphetamine, cyclic antidepressants, calcium channel blockers, beta-blockers, and digoxin. The authors review treatment controversies and emphasize the acute aspects of toxicity commonly seen in the emergency
R W, Derlet, B Z, Horowitz
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Expert Opinion on Drug Safety, 2011
Anthracyclines are widely prescribed anticancer agents that cause a dose-related cardiotoxicity, often aggravated by nonanthracycline chemotherapeutics or new generation targeted drugs. Anthracycline cardiotoxicity may occur anytime in the life of cancer survivors.
Pierantonio, Menna +5 more
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Anthracyclines are widely prescribed anticancer agents that cause a dose-related cardiotoxicity, often aggravated by nonanthracycline chemotherapeutics or new generation targeted drugs. Anthracycline cardiotoxicity may occur anytime in the life of cancer survivors.
Pierantonio, Menna +5 more
openaire +2 more sources
Annals of Pharmacotherapy, 1994
OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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OBJECTIVE: To review the clinical manifestations, postulated mechanisms, and therapeutic implications of fluorouracil-induced cardiac toxicity. DATA SOURCE: A MEDLINE search was used to identify pertinent literature. STUDY SELECTION: Studies and case reports on fluorouracil cardiotoxicity were identified through a MEDLINE search.
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Journal of Molecular and Cellular Cardiology, 1985
The morphologic-functional correlative studies that we have carried out in the past 25 years with the various catecholamines have served as an example for analyzing myocardial reaction patterns and the reactions of the cardiac muscle cells to insult.
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The morphologic-functional correlative studies that we have carried out in the past 25 years with the various catecholamines have served as an example for analyzing myocardial reaction patterns and the reactions of the cardiac muscle cells to insult.
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CARDIOTOXICITY OF AMITRIPTYLINE
The Lancet, 1972Abstract A hospital-based drug-information system has been used to extend preliminary work on the incidence of sudden unexpected death in patients with a diagnosis of cardiac disease who had been prescribed amitriptyline. The finding that there were 13 sudden unexpected deaths in a group of 119 amitriptyline patients compared with only 3 in a ...
D C, Moir +6 more
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[Anthracycline cardiotoxicity].
La Clinica terapeutica, 2003To provide specialists and general practitioners with a review of the more recent data about anthracycline-induced cardiotoxicity and diagnostic methods utilized to reveal it.Reviewers identified studies concerning anthracycline cardiotoxicity, with special emphasis to those dealing with its pathogenesis and tools utilized for diagnosing it, by ...
FINOLEZZI E +3 more
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FATAL THIORIDAZINE CARDIOTOXICITY
Medical Journal of Australia, 1979A case of fatal cardiotoxicity after a deliberate ingestion of 5000 mg thioridazine (Melleril) is reported. The serum thioridazine level is documented for the first time at the time of arrhythmia. Correct treatment of similar cases should often include insertion of a transvenous pacing wire, as the arrhythmias are generally resistant to drug therapy.
K R, Burgess +2 more
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