Results 221 to 230 of about 97,116 (340)

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

PHB1 Attenuates Triptolide-induced Cardiotoxicity by Regulating Mitochondrial Dynamics in Cultured Newborn Mice Cardiomyocytes. [PDF]

J Cardiovasc Pharmacol
Chen W, Li X.
europepmc   +1 more source

ABNORMAL CARDIAC PHENOTYPE IN PATIENTS WITH EARLY-STAGE BREAST CANCER AT LOW RISK FOR CARDIOTOXICITY [PDF]

Kai Yi Wu, Amy A. Kirkham, Mark J. Haykowsky, Edith Pituskin, Richard Thompson, Dean B. Paterson   +5 more
openalex   +1 more source

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

The Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson, Joan Escobar, Kira Kuraoka, Ian Venter, Cielo A. Carnate, Matthew W. Kay, David Mendelowitz, Kathryn J. Schunke   +7 more
wiley   +1 more source

Biomarkers and Cardiotoxicity in Breast Cancer: A Step Forward and More Studies Needed. [PDF]

JACC CardioOncol
Baik AH.
europepmc   +1 more source

Gap junction modulators: Prospects in bupropion cardiotoxicity

Lorenzo Losso, Massimo Carollo, Giorgio Ricci   +2 more
openalex   +1 more source

Protamine-induced Cardiotoxicity Is Prevented by Anti-TNF-α Antibodies and Heparin [PDF]

, 2001
Dmitry Pevni, Inna Frolkis, Adrian Iaina, Yoram Wollman, Tamara Chernichovski, Izhak Shapira, Josef Paz, Amir Kramer, Chaim Loker, Rephael Mohr   +9 more
openalex   +1 more source

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero, Jairo Rodríguez Padilla, Nicolas Cedilnik, Buntheng Ly, Juan F. Gomez, Maxime Sermesant, Mihaela Pop, Beatriz Trenor   +7 more
wiley   +1 more source

Artificial Intelligence-Enabled Electrocardiogram for the Detection and Management of Cancer Therapy-Related Cardiotoxicity. [PDF]

Cancer Innov
Song W, Gao R, Liu T.
europepmc   +1 more source

Soluble neprilysin is associated with myocardial damage and systolic dysfunction in an animal model of doxorubicin-induced cardiotoxicity. [PDF]

Cardiooncology
Sobiborowicz-Sadowska AM, Kamińska K, Sztechman D, Matusik K, Koperski Ł, Borensztejn K, Cudnoch-Jędrzejewska A.   +6 more
europepmc   +1 more source