Results 61 to 70 of about 3,873,787 (338)

The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity

Molecular Oncology, EarlyView.
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause, Rixa‐Mareike Köhn, Christian Ickes, Julia Lenger, Jonas Fischer, Sabrina Cappello, Ivan Bogeski   +6 more
wiley   +1 more source

A core curriculum for the continuing professional development of nurses: Developed by the Education Committee on behalf of the Council on Cardiovascular Nursing and Allied Professions of the ESC [PDF]

, 2015
Background: The European Society of Cardiology and the Council on Cardiovascular Nursing and Allied Professions share a vision; to decrease the burden of cardiovascular disease in Europe.
Astin, Felicity, Carroll, D. L., Hinterbuchner, L., Ketchell, A., Kletsiou, E., Ruppar, T., Serafin, A., Uchmanowicz, I.   +7 more
core   +1 more source

Coriandrum sativum L.: A Review on Ethnopharmacology, Phytochemistry, and Cardiovascular Benefits

Molecules, 2021
Coriandrum sativum (C. sativum), belonging to the Apiaceae (Umbelliferae) family, is widely recognized for its uses in culinary and traditional medicine. C.
Nisa Najibah Mahleyuddin, Said Moshawih, Long Chiau Ming, Hanis Hanum Zulkifly, Nurolaini Kifli, Mei Jun Loy, Md. Moklesur Rahman Sarker, Yaser Mohammed Al-Worafi, Bey Hing Goh, Shobna Thuraisingam, Hui Poh Goh   +10 more
doaj   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

The role of the ketogenic diet in the treatment and prevention of diseases: A literature review

Quality in Sport
In recent years the ketogenic diet (KD) has become more and more popular. This diet is used not only to reduce weight but also there are an increasingly amount of new researches with multiple possitives effects in some diseases, such as prevention in ...
Dawid Barański, Julia Skwara, Anna Salińska, Marcin Wasilewski, Konstancja Węgrzyn, Maciej Nowicki, Gustaw Laskowski, Agnieszka Góra, Piotr Węgrzyn, Natalia Dąbrowska   +9 more
doaj   +3 more sources

NO in the cardiovascular system [PDF]

Cardiovascular Research, 1999
A focused issue on nitric oxide (NO) is timely within a year of the award of the Nobel Prize for Biology and Medicine to the discovery of the fundamental roles of this simple gas in cardiovascular physiology and pathophysiology. At the time of the seminal report by Furchgott and Zawadzki of a labile endothelium-derived relaxing factor (EDRF ...
Patrick Vallance, David G. Harrison, Ajay M. Shah   +2 more
openaire   +3 more sources

An efficient strategy for producing RNA‐free Nucleocapsid protein of SARS‐CoV‐2 for biochemical and structural investigations

FEBS Open Bio, EarlyView.
Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley   +1 more source

The cardiovascular phenotype of adult patients with phenylketonuria [PDF]

, 2019
BACKGROUND: Patients with Phenylketonuria (PKU) are exposed to multiple cardiovascular risk factors, but the clinical significance of these abnormalities is yet unknown.
Azabdaftari, Aline, Giet, Markus van der, Hennermann, Julia B., Plöckinger, Ursula, Querfeld, Uwe, Schuchardt, Mirjam   +5 more
core   +1 more source

Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024

FEBS Open Bio, EarlyView.
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior, Michaela Kocholata, Marilena E. Lekka, Olga Janouskova, Moran Yadid, Maja Kosanovic   +5 more
wiley   +1 more source

Salt intake, stroke, and cardiovascular disease : meta-analysis of prospective studies [PDF]

, 2009
Objective: To assess the relation between the level of habitual salt intake and stroke or total cardiovascular disease outcome. Design: Systematic review and meta-analysis of prospective studies published 1966-2008.
Cappuccio, Francesco, Elia, Lanfranco d', Kandala, Ngianga-Bakwin, Strazzullo, Pasquale   +3 more
core   +2 more sources