Results 61 to 70 of about 4,518,294 (325)

Association of Selected Antipsychotic Agents With Major Adverse Cardiovascular Events and Noncardiovascular Mortality in Elderly Persons

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2015
Background Data from observational studies have raised concerns about the safety of treatment with antipsychotic agents (APs) in elderly patients with dementia, but this area has been insufficiently investigated. We performed a head-to-head comparison of
M. Sahlberg, E. Holm, G. Gislason, L. Køber, C. Torp-Pedersen, C. Andersson   +5 more
semanticscholar   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Call to action: Understanding the differences in the use of SGLT-2 inhibitors and GLP-1 receptor agonists

American Journal of Preventive Cardiology, 2023
Cardiovascular disease remains one of the most prominent global health problems and has been demonstrated to disproportionally affect certain communities.
Apurva Khedagi, Cara Hoke, Michelle Kelsey, Andrea Coviello, W. Schuyler Jones, Larry R. Jackson, II, Manesh R Patel, Rob W. McGarrah, Neha J Pagidipati, Nishant P. Shah   +9 more
doaj  

Lovastatin and coadministered antihypertensive/cardiovascular agents. [PDF]

Hypertension, 1992
Hypertension and hypercholesterolemia frequently coexist and may require concomitant drug treatments. The efficacy and safety profile of lovastatin given in the presence of antihypertensive medication was evaluated using patient subgroups identified in the Expanded Clinical Evaluation of Lovastatin (EXCEL) Study. The EXCEL study examined 8,245 patients
James L. Pool, C Dujovne, H Schnaper, C L Shear, M Downton, Sandra S. Stinnett, A N Chremos, R H Bradford   +7 more
openaire   +3 more sources

2015 Update on Acute Adverse Reactions to Gadolinium based Contrast Agents in Cardiovascular MR. Large Multi-National and Multi-Ethnical Population Experience With 37788 Patients From the EuroCMR Registry

Journal of Cardiovascular Magnetic Resonance, 2015
ObjectivesSpecifically we aim to demonstrate that the results of our earlier safety data hold true in this much larger multi-national and multi-ethnical population.BackgroundWe sought to re-evaluate the frequency, manifestations, and severity of acute ...
O. Bruder, S. Schneider, G. Pilz, A. V. Rossum, J. Schwitter, Detlev Nothnagel, M. Lombardi, S. Buss, A. Wagner, Steffen Erhard Petersen, S. Greulich, C. Jensen, E. Nagel, U. Sechtem, H. Mahrholdt   +14 more
semanticscholar   +1 more source

Avoidable Hospitalizations in Persons With Rheumatoid Arthritis: A Population‐Based Study Using Administrative Data

Arthritis Care &Research, EarlyView.
Objective We estimated incidence rates of avoidable hospitalizations by persons with rheumatoid arthritis (RA) relative to the general population. Methods We identified individuals meeting a validated case definition for RA based on International Classification of Diseases, Ninth Revision, Clinical Modification (ICD‐9‐CM) and ICD‐10‐CA codes in years ...
Dani G. Contreras, Claire E. H. Barber, J. Antonio Aviña‐Zubieta, Hude Quan, Seungwon Lee, James A. King, Cheryl Barnabe   +6 more
wiley   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun, Lingling Cui, Robert Terkeltaub, Ying Chen, Xinde Li, Xiaoyu Cheng, Tian Liu, Nicola Dalbeth, Changgui Li   +8 more
wiley   +1 more source

Gastrointestinal Perforation as a Safety Concern Among Patients With Rheumatoid Arthritis Receiving JAK Inhibitor Therapy: A Systematic Review and Network Meta‐Analysis

Arthritis Care &Research, EarlyView.
Objective Gastrointestinal perforation (GIP) is a rare and life‐threatening safety concern associated with JAK inhibitors (JAKi). We aimed to review the evidence regarding the risk of GIP associated with the use of JAKi in patients with rheumatoid arthritis (RA) using a systematic review and network meta‐analysis approach.
Thipsukhon Sathapanasiri, Manuel Meraz, Hamraz Mokri, Sajesh K Veettil, Karn Wijarnpreecha, Naomi Schlesinger, Arthur Kavanaugh, Nathorn Chaiyakunapruk   +7 more
wiley   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Astaxanthin: A Potential Therapeutic Agent in Cardiovascular Disease [PDF]

Marine Drugs, 2011
Astaxanthin is a xanthophyll carotenoid present in microalgae, fungi, complex plants, seafood, flamingos and quail. It is an antioxidant with anti-inflammatory properties and as such has potential as a therapeutic agent in atherosclerotic cardiovascular disease. Synthetic forms of astaxanthin have been manufactured.
Fassett, Robert G., Coombes, Jeff S.
openaire   +5 more sources