Results 31 to 40 of about 1,494,677 (294)

Hyperuricemia and Cardiovascular Disease

Reviews in Cardiovascular Medicine, 2017
Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research.
Ruochi Zhao, Fuxing Zhang, Dandan Zhang, Wenyuan Zheng, Jinsong Cheng, Zhenyu Xu, Shuangshuang Zhang, Ning Huangfu, Yong Wang   +8 more
openaire   +5 more sources

Cancer and Cardiovascular Disease [PDF]

Cardiology Research and Practice, 2011
Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially over the next generation. Advancement in cancer therapy and supportive care
Syed Wamique Yusuf, Carlo Cipolla, Jean-Bernard Durand, Daniel J. Lenihan   +3 more
openaire   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Workplace-based primary prevention intervention reduces incidence of hypertension: a post hoc analysis of cluster randomized controlled study

BMC Medicine, 2023
Background A workplace-based primary prevention intervention be an effective approach to reducing the incidence of hypertension (HTN). However, few studies to date have addressed the effect among the Chinese working population.
Zhen Hu, Xin Wang, Conglin Hong, Congyi Zheng, Linfeng Zhang, Zuo Chen, Haoqi Zhou, Yixin Tian, Xue Cao, Jiayin Cai, Runqing Gu, Ye Tian, Lan Shao, Zengwu Wang   +13 more
doaj   +1 more source

Testosterone and Cardiovascular Disease [PDF]

The Open Cardiovascular Medicine Journal, 2016
Cardiovascular disease [CVD] is a leading cause of mortality accounting for a global incidence of over 31%. Atherosclerosis is the primary pathophysiology underpinning most types of CVD. Historically, modifiable and non-modifiable risk factors were suggested to precipitate CVD.
Tambo, Amos, Roshan, Mohsin H.K., Pace, Nikolai Paul   +2 more
openaire   +4 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Myocarditis in the Setting of Recent COVID-19 Vaccination

Case Reports in Cardiology, 2021
We report three patients who presented with chest pain after receiving either the BNT162b2 Pfizer/BioNTech or mRNA-1273 Moderna/NIH vaccine. Clinical presentation, biomarker, and cardiac MRI supported myocarditis.
Laura Onderko, Benjamin Starobin, Amy E. Riviere, Patrick K. Hohl, Colin T. Phillips, Roisin B. Morgan, Aimee Welsh, Sanjeev A. Francis, Maxwell Eyram Afari   +8 more
doaj   +1 more source

Lipoprotein(a) in Cardiovascular Diseases [PDF]

BioMed Research International, 2013
Lipoprotein(a) (Lp(a)) is an LDL-like molecule consisting of an apolipoprotein B-100 (apo(B-100)) particle attached by a disulphide bridge to apo(a). Many observations have pointed out that Lp(a) levels may be a risk factor for cardiovascular diseases.
Malaguarnera M, Vacante M, Russo C, Malaguarnera G, Antic T, MALAGUARNERA, Lucia, BELLA, Rita, PENNISI, Giovanni, GALVANO, Fabio, Frigiola A.   +9 more
openaire   +3 more sources

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Nutrition and cardiovascular disease [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2007
This chapter looks at the correlation between nutrition and cardiovascular disease. The most common and pertinent cardiovascular diseases are myocardial infarction, stroke, peripheral vascular disease, and hypertension, which serve as a major risk factor for myocardial infarction and stroke.
Godfrey S. Getz, Catherine A. Reardon
openaire   +2 more sources