Results 41 to 50 of about 11,998,196 (407)

Gene Therapy for Cardiovascular Disease [PDF]

, 2003
The last decade has seen substantial advances in the development of gene therapy strategies and vector technology for the treatment of a diverse number of diseases, with a view to translating the successes observed in animal models into the clinic ...
Baker, Andrew H., Denby, Laura, Dishart, Kate L., Work, Lorraine M.   +3 more
core   +4 more sources

Lipoxidation in cardiovascular diseases

Redox Biology, 2019
Lipids can go through lipid peroxidation, an endogenous chain reaction that consists in the oxidative degradation of lipids leading to the generation of a wide variety of highly reactive carbonyl species (RCS), such as short-chain carbonyl derivatives and oxidized truncated phospholipids.
Gianazza, Erica, Brioschi, Maura, Fernandez, Alma Martinez, Banfi, Cristina   +3 more
openaire   +3 more sources

Walks4work: Rationale and study design to investigate walking at lunchtime in the workplace setting [PDF]

, 2012
Background: Following recruitment of a private sector company, an 8week lunchtime walking intervention was implemented to examine the effect of the intervention on modifiable cardiovascular disease risk factors, and further to see if walking environment ...
A Alwan, A Puig-Ribera, AJ Hautala, AJ Minisi, AJ Nelson, BJ Park, C Tudor-Locke, CB Chan, CL Craig, CR Cole, CR Cole, D Watson, Daniel K Brown, Department of Health, Department_of_Health, DP Zipes, DR Seals, EK Nisbet, EM Murtagh, EO Nishime, G Borg, GE Billman, GE Duncan, GJ Welk, GR Sandercock, H Hemingway, H Tsuji, HE Brown, I Hess, J Barton, J Barton, J Pretty, J Pretty, J Pretty, J Stevens, Jo L Barton, JP Buckley, Jules Pretty, K Sykes, KY Chen, LW Rystedt, M Rosenberg, MH Murphy, MS Penn, MT La Rovere, MT La Rovere, N Gilson, NA King, Q Li, R Rosmond, RP Juster, RW Hoyt, S Cohen, S Ogoh, SB Racette, SN Blair, T Chandola, T Cox, T Hartig, Task Force, Valerie F Gladwell, VF Gladwell, VS Conn, WB Schaufeli, WB Schaufeli, WHO, WHO, WHO, WL Haskell, X Jouven   +69 more
core   +2 more sources

Associations of epicardial fat thickness and circulating markers of myocardial fibrosis in patients with myocardial infarction

Атеросклероз, 2020
Aim: to determine the association of the thickness of epicardial adipose tissue (EAT) with the level of biological markers and the degree of myocardial fibrosis one year after myocardial infarction (MI) in patients with visceral obesity (VO ...
E. V. Belik, O. V. Gruzdeva, Yu. A. Dileva, D. A. Borodkina, N. K. Brel, E. E. Bychkova, T. B. Pecherina, V. N. Karetnikova, V. V. Kashtalap, E. I. Palicheva, A. A. Kuzmina, E. V. Fanaskova, O. L. Barbarash   +12 more
doaj   +1 more source

Lipoprotein(a): A Genetically Determined, Causal, and Prevalent Risk Factor for Atherosclerotic Cardiovascular Disease: A Scientific Statement From the American Heart Association.

Arteriosclerosis, Thrombosis and Vascular Biology, 2021
High levels of lipoprotein(a) [Lp(a)], an apoB100-containing lipoprotein, are an independent and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms associated with increased atherogenesis, inflammation, and thrombosis. Lp(a)
G. Reyes-Soffer, H. Ginsberg, L. Berglund, P. Duell, S. Heffron, P. Kamstrup, D. Lloyd‐Jones, S. Marcovina, C. Yeang, M. Koschinsky   +9 more
semanticscholar   +1 more source

Salt intake, stroke, and cardiovascular disease : meta-analysis of prospective studies [PDF]

, 2009
Objective: To assess the relation between the level of habitual salt intake and stroke or total cardiovascular disease outcome. Design: Systematic review and meta-analysis of prospective studies published 1966-2008.
Cappuccio, Francesco, Elia, Lanfranco d', Kandala, Ngianga-Bakwin, Strazzullo, Pasquale   +3 more
core   +2 more sources

High neutrophil to lymphocyte ratio with type 2 diabetes mellitus predicts poor prognosis in patients undergoing percutaneous coronary intervention: a large-scale cohort study

Cardiovascular Diabetology, 2022
Background Inflammation plays a crucial role in the pathogenesis and progression of coronary artery disease (CAD). The neutrophil to lymphocyte ratio (NLR) is a novel inflammatory biomarker and its association with clinical outcomes in CAD patients with ...
Jining He, Xiaohui Bian, Chenxi Song, Rui Zhang, Sheng Yuan, Dong Yin, Kefei Dou   +6 more
doaj   +1 more source

Pseudogenes in Cardiovascular Disease [PDF]

Frontiers in Molecular Biosciences, 2021
Cardiovascular disease is the main disease that affects human life span. In recent years, the disease has been increasingly addressed at the molecular levels, for example, pseudogenes are now known to be involved in the pathogenesis and development of cardiovascular diseases.
Songtao An, Dongchang Chen, Xi Wang, Wenbo Li, Hua Meng, Yanyan Qi   +5 more
openaire   +3 more sources

Circulating choline levels are associated with prognoses in patients with pulmonary hypertension: a cohort study

BMC Pulmonary Medicine, 2023
Backgrounds Mounting evidences have highlighted the association between metabolites and cardiovascular diseases. Our previous works have demonstrated that circulating metabolite, trimethylamine oxide, was associated with prognosis of patients with ...
Yicheng Yang, Beilan Yang, Bingyang Liu, Yanru Liang, Qin Luo, Zhihui Zhao, Zhihong Liu, Qixian Zeng, Changming Xiong   +8 more
doaj   +1 more source

Alcohol Consumption and Cardiovascular Disease

Circulation Genomic and Precision Medicine, 2020
Supplemental Digital Content is available in the text. Background: The causal role of alcohol consumption for cardiovascular disease remains unclear. We used Mendelian randomization (MR) to predict the effect of alcohol consumption on 8 cardiovascular ...
S. Larsson, Stephen Burgess, A. Mason, K. Michaëlsson   +3 more
semanticscholar   +1 more source