Results 231 to 240 of about 1,188,706 (294)

Long‐Lasting Auditory and Vestibular Recovery Following Gene Replacement Therapy in a Novel Usher Syndrome Type 1c Mouse Model

Advanced Science, EarlyView.
This study shows that gene replacement therapy using the AAV2/Anc80L65 virus can successfully restore hearing and balance in Ush1c knockout mice. The treatment leads to lasting improvements in both auditory and vestibular functions, highlighting its potential as a therapeutic approach for genetic hearing loss and vestibular disorders in humans ...
Weinan Du, Jun Huang, Aizhen Zhang, Fangfang Zhao, Tianwen Chen, Quinn M. McDermott, Tony Zheng, Haibo Wang, Rongli Zhang, Xiaolin Zhang, Jerome Allison, Hong Zhu, Wu Zhou, Qing Yin Zheng   +13 more
wiley   +1 more source

Editorial: Inflammaging and immunosenescence: role in aging-associated cardiovascular diseases. [PDF]

Front Cardiovasc Med
Barhoumi T, Bouchareb R, Alroqi F, Nefzi A, Todryk S.   +4 more
europepmc   +1 more source

Studies on an applicability of heart measurement by means of fluorography, with especial reference to mass survey of cardiovascular diseases

, 1960
Akio Okada
openalex   +2 more sources

Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy

Advanced Science, EarlyView.
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao, Tian Shen, Shengda Cao, Ziyi Liu, Wendu Pang, Meixuan Li, Jingjing Liu, Wen Li, Yunhao Wu, Chengcheng Liu, Ming Xia, Xiaolong Fu, Cheng Cheng   +12 more
wiley   +1 more source

A diagnostic prediction model for cardiovascular diseases (CVDs) in patients with psoriasis. [PDF]

Front Cardiovasc Med
Guo XY, Xue GH, Zou YM, Chen JQ, Chen S, Zhou DM.   +5 more
europepmc   +1 more source

Radiographic Appearances of Pulmonary Complications in Cardiovascular Disease

, 1961
Shuichi Hatano, Kiyoichi HIROTA, Tatsuya Momose, Makoto Murao   +3 more
openalex   +2 more sources

Development and Validation of Machine Learning‐Based Marker for Early Detection and Prognosis Stratification of Nonalcoholic Fatty Liver Disease

Advanced Science, EarlyView.
This study constructs a stacked multimodal machine learning model for nonalcoholic fattly liver disease (NAFLD) by integrating genetic and clinical features, and synthesize an in‐silico quantitative marker (ISNLD) that enables personalized risk stratification for intrahepatic and extrahepatic outcomes of high‐risk individuals of NAFLD.
Lushan Xiao, Lin Zeng, Jiaren Wang, Chang Hong, Ziyong Zhang, Chengkai Wu, Hao Cui, Yan Li, Ruining Li, Shengxing Liang, Qijie Deng, Wenyuan Li, Xuejing Zou, Pengcheng Ma, Li Liu   +14 more
wiley   +1 more source

Role and research progress of histone modification in cardiovascular diseases (Review). [PDF]

Exp Ther Med
Qi Q, Li L, Liang H, Zeng Y.
europepmc   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

A Rare Case of Spontaneous Closure of Left Ventricular Free-wall Rupture After Acute Myocardial Infarction

Journal of Cardiovascular Magnetic Resonance
Ljiljana Rankovic-Nicic, MD, Milica Dragicevic-Antonic, MD, Robert Manka, MD, FSCMR, Maja Pirnat, PhD, FSCMR, Vladimir Mihajlovic, MD, Zelimir Antonic, MD, Snezana Tajic, MD, Petar Vukovic, MD, PhD, Milovan Bojic, MD, PhD, Goran Loncar, MD, PhD   +9 more
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