Results 41 to 50 of about 1,188,706 (294)

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Predictive accuracy of systolic blood pressure to left ventricular end-diastolic pressure ratio versus TIMI score for short-term mortality after primary percutaneous coronary intervention [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research
Introduction: Aim of this study was to evaluate the predictive performance of systolic blood pressure (SBP) to left ventricular end-diastolic pressure (LVEDP) ratio for the prediction of in-hospital and short-term mortality in a contemporary cohort of ...
Rajesh Kumar   +13 more
doaj   +1 more source

MicroRNA and Cardiovascular Disease [PDF]

open access: yesBioMed Research International, 2015
Cardiovascular disease (CVD) is the leading cause of death and a major financial burden in most developed countries around the world, resulting in an estimated death toll of 17 million people in 2011. During the past decade, there have been significant advances in our knowledge of the pathogenesis, diagnosis, and treatment in CVD.
Xiao-Bo Liao   +4 more
openaire   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

INFLUENCE OF CARDIOVASCULAR DISEASES ON SALIVARY PARAMETERS

open access: yesRomanian Journal of Medical and Dental Education, 2017
Cardiovascular diseases are a major group of diseases with increased prevalence among the population. Antihypertensive drugs are incriminated as responsible for reducing salivary flow and harm to oral health. The purpose of this study was to evaluate the
Carina Balcoș   +3 more
doaj  

A Retrospective Analysis of Self-Limiting Fever following Percutaneous Patent Foramen Ovale and Atrial Septal Defect Closure

open access: yesCardiology Research and Practice
While percutaneous closure of patent foramen ovale (PFO) and atrial septal defect (ASD) are generally well-tolerated procedures, the development of postprocedure fever has been observed at a higher frequency than reported in the initial device trials. We
Francesca Galasso   +6 more
doaj   +1 more source

Factors associated with in-hospital mortality after coronary artery bypass grafting in patients with CHD and type 2 diabetes

open access: yesСахарный диабет, 2014
Coronary artery bypass grafting (CABG) is the main method used for myocardial revascularisation in patients with diabetes mellitus (DM), and determining the factors affecting the outcomes of CABG in these patients is important. Objective.
Aleksey Nikolaevich Sumin   +5 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Um novo índice de doppler tecidual para a predição de fibrilação atrial futura em pacientes com insuficiência cardíaca

open access: yesArquivos Brasileiros de Cardiologia, 2011
FUNDAMENTO: O aparecimento de Fibrilação Atrial (FA) em pacientes com Insuficiência Cardíaca (IC) está em geral associado a uma alta ocorrência de complicações cardiovasculares.
Cristian Mornos   +5 more
doaj  

Predictors and Clinical Outcomes of Vasoplegia in Patients Bridged to Heart Transplantation With Continuous‐Flow Left Ventricular Assist Devices

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background The presence of a durable left ventricular assist device (LVAD) is associated with increased risk of vasoplegia in the early postoperative period following heart transplantation (HT).
Rabea Asleh   +13 more
doaj   +1 more source

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