Results 41 to 50 of about 11,294,687 (338)

Genetic Testing for Inherited Cardiovascular Diseases: A Scientific Statement From the American Heart Association.

Circulation Genomic and Precision Medicine, 2020
Advances in human genetics are improving the understanding of a variety of inherited cardiovascular diseases, including cardiomyopathies, arrhythmic disorders, vascular disorders, and lipid disorders such as familial hypercholesterolemia.
K. Musunuru, R. Hershberger, S. Day, N. J. Klinedinst, A. Landstrom, V. Parikh, Siddharth K. Prakash, C. Semsarian, A. Sturm   +8 more
semanticscholar   +1 more source

C-reactive protein: associations with haematological variables, cardiovascular risk factors and prevalent cardiovascular disease [PDF]

, 2003
C-reactive protein (CRP) has been proposed as a risk factor for cardiovascular disease; however, this association is confounded by mutual relationships with both classical and haematological cardiovascular risk factors. We, therefore, measured CRP with a
Ann Rumley, Crombie, Cushman, Danesh, Danesh, Danesh, Ford, Fröhlich, Gordon D. O. Lowe, Gussekloo, Hak, Hugh Tunstall-Pedoe, Hutchison, Imhof, Lagrand, Lowe, Lowe, Lowe, Lowe, Lowe, Mark Woodward, Mendall, Office of Population Censuses and Surveys, Ridker, Ridker, Smith, Vuilleumier, Woodward, Woodward, Woodward, World Health Organisation Principal Investigators, Yudkin   +31 more
core   +1 more source

The role of statin drugs in combating cardiovascular diseases –A review [PDF]

, 2011
Statins clearly confer substantial benefit in people with established cardiovascular (CV) disease. Increased cholesterol levels have been associated with cardiovascular diseases (CVD), and statins are therefore used in the prevention of these diseases ...
Suresh Pichandi , Palanisamy Pasupathi, Y.Yagneswara Rao, Jawahar Farook, Athimoolam Ambika, Babu Shankar Ponnusha , Sathiyamoorthy Subramaniyam, Rajaram Virumandy, Boopathi subramaniyam Int J Cur Sci Res.
core  

Deep coverage whole genome sequences and plasma lipoprotein(a) in individuals of European and African ancestries. [PDF]

, 2018
Lipoprotein(a), Lp(a), is a modified low-density lipoprotein particle that contains apolipoprotein(a), encoded by LPA, and is a highly heritable, causal risk factor for cardiovascular diseases that varies in concentrations across ancestries. Here, we use
Alver, Maris, Bloom, Jonathan, Budoff, Matthew, Chaffin, Mark, Correa, Adolfo, Cupples, L Adrienne, Daly, Mark J, Engreitz, Jesse, Ernst, Jason, Esko, Tonu, Fu, Mao, Ganna, Andrea, Handsaker, Robert E, Johnson, W Craig, Kathiresan, Sekar, Kellis, Manolis, Manichaikul, Ani, McCarroll, Steven, Metspalu, Andres, Mitchell, Braxton D, Natarajan, Pradeep, Neale, Benjamin M, NHLBI TOPMed Lipids Working Group, Peloso, Gina M, Post, Wendy, Poterba, Timothy, Rich, Stephen S, Ripatti, Samuli, Rotter, Jerome I, Ruotsalainen, Sanni, Ryan, Kathleen A, Salomaa, Veikko, Seed, Cotton, Surakka, Ida, Tsai, Michael, Vasan, Ramachandran S, Wilson, James G, Yang, Chaojie, Zekavat, Seyedeh M   +38 more
core   +1 more source

Menopause and cardiovascular disease [PDF]

Journal of Mid-life Health, 2019
Menopausal health demand priority in Indian scenario due to increase in life expectancy and growing population of menopausal women. Time demands to promote a multidisciplinary, multi-factorial, comprehensive approach to the care of these women. By the medium of this editorial and our experience in dealing women in advancing age in and around menopause,
Ranu Patni, Annil Mahajan, Varun Gupta
openaire   +3 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

The role of mitochondrial dynamics in cardiovascular diseases

British Journal of Pharmacology, 2020
The process of mitochondrial dynamics is emerging as a core player in cardiovascular homeostasis. This process refers to the co‐ordinated cycles of biogenesis, fusion, fission and degradation to which mitochondria constantly undergo to maintain their ...
Maurizio Forte, L. Schirone, P. Ameri, C. Basso, D. Catalucci, Jessica Modica, C. Chimenti, L. Crotti, G. Frati, S. Rubattu, G. Schiattarella, D. Torella, C. Perrino, C. Indolfi, S. Sciarretta   +14 more
semanticscholar   +1 more source

Hyperuricemia and Cardiovascular Disease

Reviews in Cardiovascular Medicine, 2017
Purine metabolism in the circulatory system yields uric acid as its final oxidation product, which is believed to be linked to the development of gout and kidney stones. Hyperuricemia is closely correlated with cardiovascular disease, metabolic syndrome, and chronic kidney disease, as attested by the epidemiological and empirical research.
Ruochi Zhao, Fuxing Zhang, Dandan Zhang, Wenyuan Zheng, Jinsong Cheng, Zhenyu Xu, Shuangshuang Zhang, Ning Huangfu, Yong Wang   +8 more
openaire   +5 more sources

Cancer and Cardiovascular Disease [PDF]

Cardiology Research and Practice, 2011
Cancer and cardiovascular disease (CVD) are the two most common causes of mortality and morbidity worldwide. The incidence of both cancer and cardiovascular disease increases with age. With increased life expectancy, the burden of both these diseases will increase substantially over the next generation. Advancement in cancer therapy and supportive care
Syed Wamique Yusuf, Carlo Cipolla, Jean-Bernard Durand, Daniel J. Lenihan   +3 more
openaire   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, EarlyView.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source