Results 71 to 80 of about 9,640,042 (194)

Topological Data Analysis Identified Prognostically-Distinct Phenotypes in Transcatheter Edge-to-Edge Repair Patients

Mayo Clinic Proceedings: Digital Health, 2023
Objective: To identify prognostically distinct phenotype clusters in transcatheter edge-to-edge repair (TEER) patients based on topological data analysis (TDA), which was never used to assess the heterogeneous TEER population.
Chieh-Ju Chao, MD, Timothy Barry, MB, BCh, BAO, Amith Seri, MBBS, Ahmed El Shaer, MBBS, Nadia Chavez Ponce, MD, Soham Chakraborty, BS, Sean Smith, MD, Mohamad Alkhouli, MD, Jeremy Thaden, MD, David Fortuin, MD, John P. Sweeney, MD, Mackram Eleid, MD, Charanjit S. Rihal, MD, David R. Holmes, MD, Peter M. Pollak, MD, Abdallah El Sabbagh, MD, Steven J. Lester, MD, Jae K. Oh, MD, Win-Kuang Shen, MD, Imon Banerjee, PhD, Reza Arsanjani, MD   +20 more
doaj  

Bioabsorbable bypass grafts biofunctionalised with RGD have enhanced biophysical properties and endothelialisation tested in vivo

Frontiers in Pharmacology, 2016
Small diameter arterial bypass grafts are considered as unmet clinical need since the current grafts have poor patency of 25% within 5 years. We have developed a 3D scaffold manufactured from natural and synthetic biodegradable polymers, poly(3 ...
Larisa V Antonova, Anton G. Kutikhin, Alexander Marcus Seifalian, Alexander Marcus Seifalian, Victoria V Sevostyanova, Evgeniya O Krivkina, Andrey V Mironov, Andrey Yu Burago, Elena A Velikanova, Vera G Matveeva, Tatiana V Glushkova, Evgeniya A Sergeeva, Georgiy Yu Vasyukov, Yuliya A Kudryavtseva, Olga L Barbarash, Leonid S Barbarash   +15 more
doaj   +1 more source

NLRP3 Inflammasome and Its Central Role in the Cardiovascular Diseases

Oxidative Medicine and Cellular Longevity, 2020
Materials The NLRP3 inflammasome controls the activation of the proteolytic enzyme caspase-1. Caspase-1 in turn regulates the maturation of the proinflammasome cytokines IL-1β and IL-18, which leads to an inflammatory response.
Y. Tong, Zhihong Wang, Li Cai, Liangqiang Lin, Jiafa Liu, Jinquan Cheng   +5 more
semanticscholar   +1 more source

A Retrospective Analysis of Self-Limiting Fever following Percutaneous Patent Foramen Ovale and Atrial Septal Defect Closure

Cardiology Research and Practice
While percutaneous closure of patent foramen ovale (PFO) and atrial septal defect (ASD) are generally well-tolerated procedures, the development of postprocedure fever has been observed at a higher frequency than reported in the initial device trials. We
Francesca Galasso, Felicia Wassenaar, Timothy Barry, Omar J. Baqal, Donald J. Hagler, John P. Sweeney, F. David Fortuin   +6 more
doaj   +1 more source

Predictive accuracy of systolic blood pressure to left ventricular end-diastolic pressure ratio versus TIMI score for short-term mortality after primary percutaneous coronary intervention [PDF]

Journal of Cardiovascular and Thoracic Research
Introduction: Aim of this study was to evaluate the predictive performance of systolic blood pressure (SBP) to left ventricular end-diastolic pressure (LVEDP) ratio for the prediction of in-hospital and short-term mortality in a contemporary cohort of ...
Rajesh Kumar, Naveed Ullah Khan, Ali Bin Naseer, Zille Huma, Kalsoom Chachar, Maryam Samad, Muhammad Ishaq, Abiha Urooj, Uroosa Safdar, Muhammad Rasool, Sohail Khan, Jawaid Akbar Sial, Tahir Saghir, Nadeem Qamar   +13 more
doaj   +1 more source

miRNAS in cardiovascular diseases: potential biomarkers, therapeutic targets and challenges

Acta Pharmacologica Sinica, 2018
Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the world. Although considerable progress has been made in the diagnosis, treatment and prognosis of CVD, there is still a critical need for novel diagnostic biomarkers and
Shanshan Zhou, Jing-peng Jin, Ji-qun Wang, Zhiguo Zhang, J. Freedman, Yang Zheng, L. Cai   +6 more
semanticscholar   +1 more source

MicroRNA and Cardiovascular Disease [PDF]

BioMed Research International, 2015
Cardiovascular disease (CVD) is the leading cause of death and a major financial burden in most developed countries around the world, resulting in an estimated death toll of 17 million people in 2011. During the past decade, there have been significant advances in our knowledge of the pathogenesis, diagnosis, and treatment in CVD.
Xiao-Bo Liao, Vinicio A. de Jesus Perez, Magdalena Król, Chi-Hsiao Yeh, Ling-Qing Yuan   +4 more
openaire   +2 more sources

Low-Dose Gallic Acid Administration Does Not Improve Diet-Induced Metabolic Disorders and Atherosclerosis in Apoe Knockout Mice

Journal of Immunology Research, 2022
Diets rich in polyphenols are known to be beneficial for cardiovascular health. Gallic acid (GA) is a plant-derived triphenolic chemical with multiple cardio-protective properties, such as antiobesity, anti-inflammation, and antioxidation.
Jie Bai, Qiu-Yue Lin, Xiangbo An, Shuang Liu, Yao Wang, Yunpeng Xie, Jiawei Liao   +6 more
doaj   +1 more source

Integrative Single-Cell Analysis of Cardiomyopathy Identifies Differences in Cell Stemness and Transcriptional Regulatory Networks among Fibroblast Subpopulations

Cardiology Research and Practice
Background. Cardiomyopathy encompasses a broad spectrum of diseases affecting myocardial tissue, characterized clinically by abnormalities in cardiac structure, heart failure, and/or arrhythmias.
Wenyang Nie, Zhijie Zhao, Yuhang Liu, Youcao Wang, Jingwen Zhang, Ying Hu, Yang Liu, Yong Wang, Zhen Wang   +8 more
doaj   +1 more source

Microbiome and Cardiovascular Disease [PDF]

, 2020
AbstractAtherosclerotic cardiovascular disease (ASCVD) is a prime example of a systems disease. In the initial phase, apolipoprotein B-containing cholesterol-rich lipoproteins deposit excess cholesterol in macrophage-like cells that subsequently develop into foam cells.
Herrema, Hilde, Nieuwdorp, Max, Groen, Albert K.   +2 more
openaire   +5 more sources