Results 121 to 130 of about 886,388 (315)

The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) as a predictor of all-cause and cardiovascular mortality in US adults with diabetes or prediabetes: NHANES 1999–2018

BMC Medicine
Background The non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) serves as a novel composite lipid indicator for atherosclerosis. However, the association between NHHR and mortality in patients with diabetes or
Binyang Yu, Min Li, Zongliang Yu, Tao Zheng, Xue Feng, Anran Gao, Haoling Zhang, Rui Gao   +7 more
doaj   +1 more source

Fine particle components and health--a systematic review and meta-analysis of epidemiological time series studies of daily mortality and hospital admissions.

, 2015
Short-term exposure to fine particle mass (PM) has been associated with adverse health effects, but little is known about the relative toxicity of particle components.
H Ross Anderson, Inga C Mills, Heather A Walton, Anderson, HR, Anderson, Ross, Mills, IC, Richard W Atkinson, Atkinson, RW, Mills, Inga, Walton, Heather, Walton, HA, Atkinson, Richard   +11 more
core   +1 more source

Autoimmune Encephalitis in Acute Care—Pathology, Diagnosis, and Management

Advanced Science, EarlyView.
ABSTRACT Autoimmune encephalitis (AE) is characterized by immune‐mediated inflammation of the brain parenchyma, presenting with various neurological syndromes, including but not limited to seizures, altered consciousness, neuropsychiatric symptoms, and movement disorders.
Suneesh Thilak, David Okoh, William Scotton, Shanika Samarasekera, Vikram Patil, Suresh Renukappa, Andrew Macduff, Subashini Suresh, Rajeev Krishnadas, Tonny Veenith   +9 more
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Prevalence of airflow limitation in outpatients with cardiovascular diseases in Japan

, 2014
Katsuya Onishi,1 Daisuke Yoshimoto,2 Gerry W Hagan,3 Paul W Jones4 1Onishi Heart Clinic, Mie, 2Medical Affairs Respiratory, GlaxoSmithKline KK, Tokyo, Japan; 3Independent Consultant, Marbella, Spain; 4Division of Clinical Science, St George's ...
Jones PW, Hagan, GW, Hagan GW, Onishi, K, Jones, PW, Onishi K, Yoshimoto D, Yoshimoto, D   +7 more
core   +1 more source

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

Advanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee, Chul‐Gyun Lim, Pothiappan Vairaprakash, Jong‐Min Kim, Jiyoon Kim, Ji‐Young Park, Klaus M. Hahn, Hyunbo Shim, Hae Woong Choi, Tobias S. Ulmer, Soon Jun Hong, Chungho Kim   +11 more
wiley   +1 more source

Impaired Glucose Metabolism among Those with and without Diagnosed Diabetes and Mortality: A Cohort Study Using Health Survey for England Data.

, 2015
The extent that controlled diabetes impacts upon mortality, compared with uncontrolled diabetes, and how pre-diabetes alters mortality risk remain issues requiring ...
Nicola J Shelton, Vanessa L Z Gordon-Dseagu, Panayotes Demakakos, Demakakos, P, Jennifer S Mindell, Andrew Steptoe, Gordon-Dseagu, VL, Steptoe, A, Jane Wardle, Alison Moody, Moody, A, Mindell, JS, Shelton, NJ, Wardle, J   +13 more
core   +1 more source

Methylglyoxal Accumulation is Associated with Brain Inflammation after Myocardial Infarction with Sex and Regional Differences

Advanced Science, EarlyView.
This study identifies that methylglyoxal may play an important role in heart‐brain interactions after myocardial infarction. Myocardial infarction leads to increased levels of methylglyoxal‐derived advanced glycation end‐products (MG‐H1) in the brain of mice, which is associated with loss of blood‐brain barrier integrity and neuroinflammation ...
Ramis Ileri, Xixi Guo, Erik J. Suuronen
wiley   +1 more source

Heat and Cardiovascular Mortality: An Epidemiological Perspective

Circulation Research
As global temperatures rise, extreme heat events are projected to become more frequent and intense. Extreme heat causes a wide range of health effects, including an overall increase in morbidity and mortality. It is important to note that while there is sufficient epidemiological evidence for heat-related increases in all-cause mortality, evidence on ...
Singh, Nidhi, Areal, Ashtyn Tracy, Breitner, Susanne, Zhang, Siqi, Agewall, Stefan, Schikowski, Tamara, Schneider, Alexandra   +6 more
openaire   +4 more sources

Organisational downsizing, sickness absence, and mortality: 10-town prospective cohort study

, 2004
Objective To examine whether downsizing, the reduction of personnel in organisations, is a predictor of increased sickness absence and mortality among employees.Design Prospective cohort study over 7.5 years of employees grouped into categories on the ...
Kivimaki, M, Virtanen, M, Virtanen, P, Vahtera, J, Pentti, J, Ferrie, JE, Linna, A   +6 more
core