Results 71 to 80 of about 36,823 (266)

Magnetic Micro‐ and Nanorobots for Precision Thrombolysis: Design Strategies and Translational Challenges

Advanced Robotics Research, EarlyView.
Micro‐ and nanorobots for targeted thrombolysis. This perspective elaborates on the clinical indication of blood clot disorders and current limitations for treatment. As a novel, alternative solution, micro‐ and nanorobots can be used to treat and break down thrombi.
Joshua M. Mesfin, Yimo Yan, Nikola Cesarovic, Simone Schuerle   +3 more
wiley   +1 more source

Physiology for engineers: applying engineering methods to physiological systems [PDF]

, 2016
This book provides an introduction to qualitative and quantitative aspects of human physiology. It looks at biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be ...
Chappell, Michael, Payne, Stephen
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

The impact of environmental factors in influencing epigenetics related to oxidative states in the cardiovascular system [PDF]

, 2017
Oxidative states exert a significant influence on a wide range of biological and molecular processes and functions. When their balance is shifted towards enhanced amounts of free radicals, pathological phenomena can occur, as the generation of reactive ...
Bordin, Antonella, Mariangela Peruzzi, Peruzzi, Mariangela, Marullo, Antonino, Chimenti, Isotta, Frati, Giacomo, Valenti, Valentina, Palmerio, Silvia, Sciarretta, Sebastiano, Pagano, Francesca, Antonino Marullo, Angelini, Francesco, Isotta Chimenti, Colin E. Murdoch, Sebastiano Sciarretta, Francesca Pagano, Silvia Palmerio, Murdoch, Colin E., Murdoch, Colin E.; id_orcid, de Falco, Elena, Schirone, Leonardo, Francesco Angelini, Valentina Valenti, Antonella Bordin, Leonardo Schirone, Milan, Marika, Giacomo Frati, Marika Milan, Elena De Falco   +28 more
core   +1 more source

Breathing patterns and associated cardiovascular changes in intermittently breathing animals: (Partially) correcting a semantic quagmire

Experimental Physiology
Many animal species do not breathe in a continuous, rhythmic fashion, but rather display a variety of breathing patterns characterized by prolonged periods between breaths (inter‐breath intervals), during which the heart continues to beat.
Warren Burggren, Andreas Fahlman, William Milsom   +2 more
doaj   +1 more source

A 3D Human Bone and Bone Marrow‐on‐a‐Chip Model for In Vitro Bone Remodeling and Immune Cell Maintenance

Advanced Science, EarlyView.
This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer, Melanie‐Jasmin Ort, Kristian Händler, Emely Bortel, Ioanna Maria Dimitriou, Martin Textor, Georg N. Duda, Janosch Schoon, Uwe Marx, Uwe Kornak, Annika Winter, Bernhard Hesse, Stefanie Donner, Sebastian Hardt, Oliver Klein, Simon Reinke, Malte Spielmann, Sven Geißler   +17 more
wiley   +1 more source

A wave propagation model of blood flow in large vessels using an approximate velocity profile function [PDF]

, 2007
Lumped-parameter models (zero-dimensional) and wave-propagation models (one-dimensional) for pressure and flow in large vessels, as well as fully three-dimensional fluid–structure interaction models for pressure and velocity, can contribute valuably to ...
Vosse, FN Frans van de, Vosse, van de, F.N.; id_orcid, Rutten, MCM Marcel, Bessems, D., Vosse, van de, F.N., Rutten, M.C.M., Bessems, D David   +6 more
core   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

A novel method for pulsometry based on traditional iranian medicine

Journal of Medical Signals and Sensors, 2015
Arterial pulse measurement is one of the most important methods for evaluation of healthy conditions. In traditional Iranian medicine (TIM), physician may detect radial pulse by holding four fingers on the patient's wrist.
Farzane Yousefipoor, Vahidreza Nafisi
doaj