Results 61 to 70 of about 2,907,819 (245)

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Effects of Tetrodotoxin on the Mammalian Cardiovascular System

Marine Drugs, 2010
The human genome encodes nine functional voltage-gated Na+ channels. Three of them, namely Nav1.5, Nav1.8, and Nav1.9, are resistant to nanomolar concentrations of tetrodotoxin (TTX; IC50 ≥ 1 μM).
Thomas Zimmer
doaj   +1 more source

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Relations Between Dispositional Expressivity and Physiological Changes During Acute Positive and Negative Affect [PDF]

, 2007
The aim of the present study is to examine the relations between emotional expressivity measured by Berkeley Expressivity Questionnaire and physiological response in situations where positive and negative affects were induced.
Hudek - Knežević, Jasna, Gračanin, Asmir, Kardum, Igor   +2 more
core   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Efeitos do intervalo de recuperação entre as séries sobre a pressão arterial após exercícios resistidos Efectos del intervalo de recuperación entre las series sobre la presión arterial luego de ejercicios de resistencia Effects of rest interval between exercise sets on blood pressure after resistance exercises

Arquivos Brasileiros de Cardiologia, 2010
FUNDAMENTO: Apesar de os estudos demonstrarem a ocorrência da hipotensão pós-exercício (HPE) em exercícios resistidos, ainda não há consenso sobre um protocolo ideal.
João Veloso, Marcos D. Polito, Tiago Riera, Rodrigo Celes, José Carlos Vidal, Martim Bottaro   +5 more
doaj  

1‐D Collocated Dual‐Gradient Sensory Fibers for Comprehensive Sensing and Decoding of Complex Human Motion and Physiology

Advanced Materials, EarlyView.
Coupled materials design enables a monolithic fiber that integrates complementary sensing regimes into a single wearable strand. By preserving informative signal features across subtle physiological deformation, large body motion, and mixed mechanical inputs, the dual‐gradient architecture generates synchronized, less redundant outputs that improve ...
Yunheum Lee, Sungha Jeon, Min Kim, Joonhee Won, Jinwook Yeo, Kyunghyun Jo, Soyeon Lee, Kieun Park, Yechan Yang, Chul Kim, Gun‐Hee Lee, Seunghwa Ryu, Sungho Jo, Seongjun Park   +13 more
wiley   +1 more source

Reframing SpO2 tolerance as a physiological switch: implications for hypoxic adaptation and exercise regulation

Frontiers in Physiology
Blood oxygen saturation (SpO2) is a widely used oxygenation index in clinical and physiological settings. However, recent phenomena, such as asymptomatic hypoxia in COVID-19 and the superior performance of athletes in high-altitude conditions under ...
Enomoto Yuri, Hui-Yu Chung, Fu-Shih Chen, Fu-Shih Chen   +3 more
doaj   +1 more source

Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies [PDF]

, 2011
BACKGROUND: Guidelines differ about the value of assessment of adiposity measures for cardiovascular disease risk prediction when information is available for other risk factors. We studied the separate and combined associations of body-mass index (BMI),
Nordestgaard, Borge G., Stehouwer, Coen; id_orcid, Kaptoge, S., Danesh, J, Wood, Angela M., Thompson, Alex, Sattar, N, Thompson, A, Wormser, D, Emerging Risk Factors Collaboration, Risérus, Ulf,, Salomma, V, Sarwar, N, Danesh, J., Wood, Angela M, Pennells, L, Ärnlöv, Johan,, Woodward, M., Salomaa, Veikko, Sundström, Johan,, Thompson, S.G., Kaptoge, S, Tybjærg-Hansen, Anne, Wormser, D., Ridker, P, Thompson, Simon G, null The Emerging Risk Factors Collaboration, Woodward, Mark, Kizer, Jorge R, Frikke-Schmidt, Ruth, Nordestgaard, BG, Kaptoge, Stephen, Salomaa, V, Lawlor, DA, Eriksson, Henry,, Sarwar, Nadeem, Wood, AM, Kizer, Jorge R., Pennells, Lisa, Stevens, June, Pennells, L., Whitlock, G, Salomaa, V., Nordestgaard, B.G., Collins, Rory, Ridker, Paul, Thompson, A., Lawlor, D.A., Woodward, M, Collins, R, Kizer, J.R., Sattar, N., Lawlor, Debbie A, Sarwar, N., Ingelsson, Erik,, Davey Smith, George, Danesh, John, Stehouwer, Coen, Ridker, P., The Emerging Risk Factors Collaboration,, Di Angelantonio, Emanuele, Wood, A.M., Whitlock, G., Di Angelantonio, E., Sattar, Naveed, Lawlor, Debbie A., Collins, R., Di Angelantonio, E, Kizer, JR, Whitlock, Gary, Thompson, SG, Nordestgaard, Børge G, Stevens, J, Wormser, David, Stevens, J., Thompson, Simon G., Di Angeloantonio, Emanuele, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.)   +77 more
core   +1 more source