Results 91 to 100 of about 10,143,464 (406)

Cardiovascular risk factors, global cardiovascular risk, and vascular age in a cohort of Peruvian HIV patients

HIV & AIDS Review. International Journal of HIV-Related Problems
Introduction Data on cardiovascular risk and vascular age in patients with human immunodeficiency virus (HIV) from developing countries are scarce. Therefore, the current study aimed to determine the prevalence of cardiovascular risk factors, global ...
German Valenzuela-Rodriguez, Jaime A. Collins, Raul Castillo, Luis R. Illescas, Adrian V. Hernandez, Carlos Diaz-Arocutipa   +5 more
doaj   +1 more source

Lipoprotein(a): A Genetically Determined, Causal, and Prevalent Risk Factor for Atherosclerotic Cardiovascular Disease: A Scientific Statement From the American Heart Association.

Arteriosclerosis, Thrombosis and Vascular Biology, 2021
High levels of lipoprotein(a) [Lp(a)], an apoB100-containing lipoprotein, are an independent and causal risk factor for atherosclerotic cardiovascular diseases through mechanisms associated with increased atherogenesis, inflammation, and thrombosis. Lp(a)
G. Reyes-Soffer, H. Ginsberg, L. Berglund, P. Duell, S. Heffron, P. Kamstrup, D. Lloyd‐Jones, S. Marcovina, C. Yeang, M. Koschinsky   +9 more
semanticscholar   +1 more source

Chemokines and Cardiovascular Risk [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2008
Based on the importance of inflammation in atherogenesis, recent work has focused on whether plasma markers of inflammation can noninvasively diagnose and prognosticate atherosclerotic disorders. Although several studies support an important pathogenic role of chemokines in atherosclerosis, potentially representing attractive therapeutic targets in ...
Pål, Aukrust, Bente, Halvorsen, Arne, Yndestad, Thor, Ueland, Erik, Øie, Kari, Otterdal, Lars, Gullestad, Jan K, Damås   +7 more
openaire   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Electronic Cigarettes and Cardiovascular Risk: Caution Waiting for Evidence

European Cardiology Review, 2019
Electronic cigarettes use is a growing trend in contemporary societies, with the propensity to compete with traditional tobacco smoking. Some preclinical studies demonstrated the toxic and detrimental effects of electronic cigarettes liquid components ...
Domenico D’Amario, Stefano Migliaro, Josip Andjelo Borovac, Rocco Vergallo, Mattia Galli, Attilio Restivo, Matteo Bonini, Enrico Romagnoli, Antonio Maria Leone, Filippo Crea   +9 more
doaj   +1 more source

Can machine-learning improve cardiovascular risk prediction using routine clinical data?

PLoS ONE, 2017
Background Current approaches to predict cardiovascular risk fail to identify many people who would benefit from preventive treatment, while others receive unnecessary intervention.
S. Weng, J. Reps, J. Kai, J. Garibaldi, N. Qureshi   +4 more
semanticscholar   +1 more source

Cardiovascular risk of smoking and benefits of smoking cessation

Journal of Thoracic Disease, 2020
Smoking increases mortality from all causes and has a crucial role in atherosclerotic cardiovascular disease (ASCVD). Active smoking and secondhand smoke exposure determine more than 30% of coronary heart disease (CHD) mortality.
G. Gallucci, A. Tartarone, R. Lerose, A. V. Lalinga, A. Capobianco   +4 more
semanticscholar   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Socioeconomic Deprivation: An Important, Largely Unrecognized Risk Factor in Primary Prevention of Cardiovascular Disease [PDF]

, 2022
Dorien M. Kimenai, Leah Pirondini, John Gregson, David Prieto‐Merino, Stuart Pocock, Pablo Perel, Tilly Hamilton, Paul Welsh, Archie Campbell, David J. Porteous, Caroline Hayward, Naveed Sattar, Nicholas L. Mills, Anoop Shah   +13 more
openalex   +1 more source

Cardiovascular risk profile and frailty in a population-based study of older British men. [PDF]

, 2014
BACKGROUND: Frailty in older age is known to be associated with cardiovascular disease (CVD) risk. However, the extent to which frailty is associated with the CVD risk profile has been little studied. Our aim was to examine the associations of a range of
Afilalo, Bastos-Barbosa, Bergmeyer, Bowers, Chang, Chaves, Clegg, Cole, Collard, Fried, Gindler, Hill, Le Couteur, Levey, Levy, Nauck, Peake, Rockwood, Stankov, Szanton, Thomas, Trinder, Walker, Weissman, Wilhelm-Leen, Xue   +25 more
core   +1 more source