Results 81 to 90 of about 2,380,266 (312)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Continued efforts to translate diabetes cardiovascular outcome trials into clinical practice [PDF]

, 2016
Diabetic patients suffer from a high rate of cardiovascular events and such risk increases with HbA1c. However, lowering HbA1c does not appear to yield the same benefit on macrovascular endpoints, as observed for microvascular endpoints. As the number of
Avogaro, Angelo, Bonora, Enzo, Fadini, GIAN PAOLO, Prato, Stefano Del, Sesti, Giorgio   +4 more
core   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Relation of Federal Taxation to the Financing of Small Business [PDF]

, 1945
Aims. To explore general practitioners’ (GPs’) descriptions of their thoughts and action when prescribing cardiovascular preventive drugs. Methods. Qualitative content analysis of transcribed group interviews with 14 participants from two primary health ...
Carl Edvard Rudebeck, Josabeth Hultberg
core   +5 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Associations between the neural-hematopoietic-inflammatory axis and DNA methylation of stress-related genes in human leukocytes: Data from the Washington, D.C. cardiovascular health and needs assessment

Brain, Behavior, & Immunity - Health
Chronic stress is associated with cardiovascular disease (CVD) risk and elevated amygdala activity. Previous research suggests a plausible connection between amygdala activity, hematopoietic tissue activity, and cardiovascular events; however, the ...
Manuel A. Cintron, Yvonne Baumer, Alina P.S. Pang, Elizabeth M. Aquino Peterson, Lola R. Ortiz-Whittingham, Joshua A. Jacobs, Sonal Sharda, Kameswari A. Potharaju, Andrew S. Baez, Cristhian A. Gutierrez-Huerta, Erika N. Ortiz-Chaparro, Billy S. Collins, Valerie M. Mitchell, Abhinav Saurabh, Laurel G. Mendelsohn, Neelam R. Redekar, Subrata Paul, Michael J. Corley, Tiffany M. Powell-Wiley   +18 more
doaj   +1 more source

Cardiovascular diseases: Risk factors [PDF]

Medicinski casopis, 2016
Objective. The aim of this study was to investigate the prevalence and impact of certain risk factors for cardiovascular diseases. Methods. Observational cross-sectional study was conducted in the Health Centre of Kragujevac, in 2014. In total, 98 people older than 35 years, with no previous diagnosis of cardiovascular diseases were chosen by simple ...
Stajic, Dalibor, Djonović, Nela
openaire   +2 more sources

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Salt intake, stroke, and cardiovascular disease : meta-analysis of prospective studies [PDF]

, 2009
Objective: To assess the relation between the level of habitual salt intake and stroke or total cardiovascular disease outcome. Design: Systematic review and meta-analysis of prospective studies published 1966-2008.
Strazzullo, Pasquale, Elia, Lanfranco d', Kandala, Ngianga-Bakwin, Cappuccio, Francesco   +3 more
core   +1 more source

Neglected cardiovascular risk factors [PDF]

European Heart Journal, 2015
Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast ![Graphic][1] Obesity and the metabolic syndrome are highly prevalent conditions. The metabolic syndrome not only precedes cardiovascular conditions, and hence represents an important cluster of risk factors,1,2 but also remains relevant in patients with established coronary artery
openaire   +3 more sources