Results 231 to 240 of about 875,736 (340)

Nursing interventions’ impact on cardiovascular complications after gastrointestinal surgery in intensive care unit: Risk factor analysis

Duo Li, Peng Yang, Xiaoshun He, Han Xia
openalex   +1 more source

Calcium Channel Blockers Inhibit Pancreatic Neuroendocrine Neoplasms Progression via Cav1.2‐Epigenetic Circuit

Advanced Science, EarlyView.
Our study reveals a novel mechanism of a positive regulatory circuit between Cav1.2 and H3K27ac for pancreatic neuroendocrine neoplasms (pNENs) progression. Cav1.2 is identified as a crucial target for promoting disease progression and correlates with malignant behaviors, which are remarkably inhibited by the administration of calcium channel blockers (
Yangyinhui Yu, Qiongcong Xu, Jinzhao Xie, Mingjian Ma, Xitai Huang, Yinhao Shi, Jiawei Zhou, Enliang Zhu, Ziyi Zhao, Ning Zhang, Zhide Liu, Jingyuan Ye, Xiaoyu Yin   +12 more
wiley   +1 more source

Risk of Postoperative Hypermagnesemia in Cardiopulmonary Bypass-Assisted Cardiovascular Surgery. [PDF]

Kidney360
Ghaddar M, Hatab T, El-Kaakour A, Tamim H, Makki M, El-Halabi T, Rifaii K, Sfeir P, Hoteit M, Koubar SH.   +9 more
europepmc   +1 more source

Consective 226 Cases of Cardiovascular Surgery in Nippon Medical School Second Hospital

, 2001
Masafumi Hioki, Yoshio Iedokoro, Nami Takushima, Mitsumasa Murano, Jun Kawamura, Naoyuki Yoshino, Yasuo Yamashita, Koan Orii, S Masuda, Shigeo Tanaka   +9 more
openalex   +2 more sources

Targeted Extracellular Vesicles Deliver Asiaticoside to Inhibit AURKB/DRP1‐Mediated Mitochondrial Fission and Attenuate Hypertrophic Scar Formation

Advanced Science, EarlyView.
Hypertrophic scar formation is driven by excessive mitochondrial fission in wound macrophages, which we discover is governed by a novel AURKB‐DRP1(Ser616) axis. The study develops a targeted therapy using cRGD‐decorated extracellular vesicles to deliver the natural compound Asiaticoside specifically to macrophages.
Luyu Li, Chenli Si, Xue Wang, Xiaojin Wu, Ying Shang, Shengfang Ge, Yong Wang, Yong Zuo, Zhen Zhang   +8 more
wiley   +1 more source

Early and Late Outcomes of Redo Procedure for Total Arch Replacement After Previous Cardiovascular Surgery: 10-Year Experience. [PDF]

Interdiscip Cardiovasc Thorac Surg
Zhao R, Wang W, Liu Y, Dun Y, Zhang B, Wang L, Zhou S, Sun X.   +7 more
europepmc   +1 more source

ECLIPSES: Early initiation of sodium glucose cotransporter‐2 inhibitors for cardiovascular protection in patients with type 2 diabetes following acute coronary syndrome and subsequent coronary artery bypass graft surgery [PDF]

Lena Makortoff, Karen L. Then, Melissa Dutchak, Meng Lin, Erik Youngson, Cheryl Harten   +5 more
openalex   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Increased neprilysin expression is linked to atrial fibrotic remodeling in cardiovascular surgery patients. [PDF]

Int J Cardiol Heart Vasc
Nakajima T, Haruyama A, Fukuda T, Minami K, Nakajima T, Hasegawa T, Tokoi S, Obi S, Oguri G, Sakuma M, Shibasaki I, Fukuda H, Toyoda S.   +12 more
europepmc   +1 more source

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source