Results 41 to 50 of about 875,736 (340)

Case Report: “Dumbbell” giant right coronary artery ectasia with right atrial fistula

Frontiers in Cardiovascular Medicine
A 50-year-old female patient presented with a “dumbbell” giant right coronary artery ectasia, characterized by two artery dilation segments both reaching the level of a giant aneurysm with a normal segment between them.
Jianggui Shan, Heng Wang, Song Xue
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Ischemic Heart Disease Selectively Modifies the Right Atrial Appendage Transcriptome

Frontiers in Cardiovascular Medicine, 2021
Background: Although many pathological changes have been associated with ischemic heart disease (IHD), molecular-level alterations specific to the ischemic myocardium and their potential to reflect disease severity or therapeutic outcome remain unclear ...
Severi Mulari, Severi Mulari, Arda Eskin, Milla Lampinen, Milla Lampinen, Annu Nummi, Tuomo Nieminen, Kari Teittinen, Teija Ojala, Matti Kankainen, Antti Vento, Jari Laurikka, Jari Laurikka, Markku Kupari, Ari Harjula, Nurcan Tuncbag, Nurcan Tuncbag, Nurcan Tuncbag, Esko Kankuri   +18 more
doaj   +1 more source

Determinants of fibrinogen in an Italian population suffering from claudication. Lower fibrinogen in the south compared to middle and north of Italy. The ADEP Group. [PDF]

, 1998
Prospective studies have shown that high plasma levels of fibrinogen are independently associated with the risk of cardiovascular complications. In patients suffering from peripheral vascular disease (PVD) fibrinogen has been shown to be an independent ...
A. Longoni, BASILI, Stefania, IULIANO, Luigi, M. Milani, M. Vieri, VIOLI, Francesco   +5 more
core  

Obesity as a risk factor following cadaveric renal transplantation [PDF]

, 1990
Obesity has generally been thought to increase the risk of operative mortality and postoperative complications in surgical patients. No data examining obesity as a factor in cadaveric renal transplantation were available.
Hakala, TR, Holley, JL, Lopatin, WB, Shapiro, R, Starzl, TE, Tzakis, AG   +5 more
core   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Evaluation of Analgesic Drug Therapy for Postoperative Pain Management in Cardiovascular Surgery

Current Therapeutic Research
: Background: Cardiovascular surgery is usually associated with higher degree of postoperative pain that influences a patient's physical recovery.
Yue Yue, MBBS, Hongyan Ji, MBBS, Shizhong Wang, PhD, Huawei Cheng, MBBS, Rongmei Wang, MSc, Haijun Qu, MSc, Jing Li, MSc   +6 more
doaj   +1 more source

Book review: Selected works on the history of medicine by academician Yuri Shevchenko

Studia Humanitatis, 2023
The collection of works by Yuri Shevchenko, Doctor of Medical Sciences and Academician of the Russian Academy of Sciences, includes speeches and articles from different years, which were delivered on memorable dates or published in medical journals ...
Belonogova Julia Igorevna
doaj