Results 11 to 20 of about 2,065,380 (330)

NO in the cardiovascular system [PDF]

Cardiovascular Research, 1999
A focused issue on nitric oxide (NO) is timely within a year of the award of the Nobel Prize for Biology and Medicine to the discovery of the fundamental roles of this simple gas in cardiovascular physiology and pathophysiology. At the time of the seminal report by Furchgott and Zawadzki of a labile endothelium-derived relaxing factor (EDRF ...
Patrick Vallance, David G. Harrison, Ajay M. Shah   +2 more
openaire   +3 more sources

Cyclooxygenases and the cardiovascular system [PDF]

Pharmacology & Therapeutics, 2021
Cyclooxygenase (COX)-1 and COX-2 are centrally important enzymes within the cardiovascular system with a range of diverse, sometimes opposing, functions. Through the production of thromboxane, COX in platelets is a pro-thrombotic enzyme. By contrast, through the production of prostacyclin, COX in endothelial cells is antithrombotic and in the kidney ...
Mitchell, Jane A, Kirkby, Nicholas S, Ahmetaj-Shala, Blerina, Armstrong, Paul C, Crescente, Marilena, Ferreira, Plinio, Lopes Pires, Maria Elisa, Vaja, Ricky, Warner, Timothy D   +8 more
openaire   +6 more sources

Role of tubular epithelial arginase-II in renal inflammaging

npj Aging and Mechanisms of Disease, 2021
The aging kidney undergoes complex changes and is vulnerable to injury and development of chronic kidney disease (CKD) with preponderance affecting more women than men.
Ji Huang, Xiujie Liang, Diogo Ladeiras, Benoit Fellay, Xiu-Fen Ming, Zhihong Yang   +5 more
doaj   +1 more source

Clinical Characteristics, Sex Differences, and Outcomes in Patients With Normal or Near‐Normal Coronary Arteries, Non‐Obstructive or Obstructive Coronary Artery Disease

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundNormal or near‐normal coronary arteries (NNCAs) or nonobstructive coronary artery disease (CAD) are found on invasive coronary angiography in ≈55% of patients. Some attribute this to frequent referral of low‐risk patients. We sought to identify
Michelle L. Ouellette, Adrián I. Löffler, George A. Beller, Virginia K. Workman, Eric Holland, Jamieson M. Bourque   +5 more
doaj   +1 more source

QTc dispersion as a novel marker in identifying patients requiring an epicardial approach for ablation of scar mediated ventricular tachycardia

Indian Pacing and Electrophysiology Journal, 2020
Introduction: Epicardial exit sites of ventricular tachycardia (VT) are frequently encountered during VT ablation requiring an epicardial ablation approach for successful elimination of VT.
Darshan Krishnappa, Baris Akdemir, Teerapat Nantsupawat, Balaji Krishnan, Ilknur Can, Selcuk Adabag, Jian-Ming Li, Venkatakrishna N. Tholakanahalli   +7 more
doaj   +1 more source

Examining the role of insulin in the regulation of cardiovascular health [PDF]

, 2013
A substantial body of evidence has reported that insulin has direct actions on the cardiovascular system independent of its systemic effects on plasma glucose or lipids.
Salt, Ian P.
core   +1 more source

The use of enoxaparin as bridge to therapeutic INR after LVAD implantation

Journal of Cardiothoracic Surgery, 2020
Background Left ventricular assist devices (LVAD) have been increasingly used in the treatment of end-stage heart failure. While warfarin has been uniformly recommended in the long-term as anticoagulation strategy, no clear recommendation exists for the ...
Zubair Shah, Ioannis Mastoris, Prakash Acharya, Aniket S. Rali, Moghni Mohammed, Sami Farhad, Sagar Ranka, Savahanna Wagner, Giorgio Zanotti, Christopher T. Salerno, Nicholas A. Haglund, Andrew J. Sauer, Ashwin K. Ravichandran, Travis Abicht   +13 more
doaj   +1 more source

Angiotensin-(1-7) and angiotensin-(1-9): function in cardiac and vascular remodeling [PDF]

, 2014
The renin angiotensin system (RAS) is integral to cardiovascular physiology, however, dysregulation of this system largely contributes to the pathophysiology of cardiovascular disease (CVD).
Akishita, Barroso, Booz, Bosnyak, Bosnyak, Brosnihan, Bruneval, Bryan, Calo, Campbell, Caroline Fattah, Castro, Chappell, Chappell, Chen, Christopher M. Loughrey, Clare A. McKinney, Clarke, Costa, Crackower, Cushman, De Mello, Dias-Peixoto, Domeier, Dong, Donoghue, Donoghue, Drummer, Faria-Silva, Ferreira, Ferreira, Ferreira, Ferreira, Flores-Munoz, Flores-Munoz, Fomovsky, Fraga-Silva, Fraga-Silva, Freeman, Galis, Gava, Gembardt, Gomes, Graeme Milligan, Grobe, Gusev, Hanke, Hannan, Harmer, Heitsch, Horiguchi, Horiuchi, Hunyady, Inaba, Iwata, Jackman, Jaiswal, Jarajapu, Kaminska, Kassiri, Katada, Kokkonen, Kramkowski, Langeveld, Lautner, Liao, Libby, Liu, Loot, Lovren, Masson, McCollum, Mehta, Mercure, Miura, Mogielnicki, Nakajima, Newby, Ng, Nouet, Ocaranza, Ocaranza, Ocaranza, Patel, Patel, Qi, Ray, Rice, Rodgers, Rodrigues-Machado, Ross, Rowe, Sampaio, Sampaio, Santos, Santos, Schultz Jel, Selvetella, Shah, Sheng-Long, Singh, Sluimer, Stegbauer, Strawn, Stuart A. Nicklin, Tallant, Tesanovic, Tipnis, Turner, Uekama, Varagic, Vickers, Vilas-Boas, Walters, Wang, Weber, West, Wiemer, Yamada, Yang, Zeng, Zhang, Zhao, Zhong   +123 more
core   +1 more source

Autophagy in the cardiovascular system [PDF]

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2009
Autophagy is a catabolic pathway for bulk turnover of long-lived proteins and organelles via lysosomal degradation. Growing evidence reveals that autophagy is involved in the progression or prevention of many human diseases. Here we discuss the role of autophagy in the normal heart, in heart disease and atherosclerosis.
De Meyer, Guido, Martinet, Wim
openaire   +2 more sources

Coronavirus Disease 2019: Where are we and Where are we Going? Intersections Between Coronavirus Disease 2019 and the Heart

Cardiac Failure Review, 2020
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which has become a pandemic affecting every country in the world.
Emilia D’Elia, Michele Senni
doaj   +1 more source